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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of vitamin D biosynthetic process
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Accession:GO:0010957 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).



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negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) BHF-UCL PMID:19502595 NCBI chr24:36,498,343...36,503,623
Ensembl chr24:36,498,062...36,503,628
JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) BHF-UCL PMID:18485278 PMID:19502595 NCBI chr29:1,154,132...1,156,653
Ensembl chr29:1,154,036...1,156,653
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13969
    metabolic process 9103
      biosynthetic process 4630
        negative regulation of biosynthetic process 1473
          negative regulation of cellular biosynthetic process 1431
            negative regulation of vitamin D biosynthetic process 5
              negative regulation of calcidiol 1-monooxygenase activity 3
Path 2
Term Annotations click to browse term
  biological_process 13969
    biological regulation 10140
      regulation of biological process 9581
        regulation of metabolic process 5750
          regulation of primary metabolic process 4811
            regulation of lipid metabolic process 358
              regulation of steroid metabolic process 105
                negative regulation of steroid metabolic process 25
                  negative regulation of steroid biosynthetic process 24
                    negative regulation of vitamin D biosynthetic process 5
                      negative regulation of calcidiol 1-monooxygenase activity 3
paths to the root