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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of protein processing
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Accession:GO:0010955 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
Synonyms:exact_synonym: negative regulation of protein maturation by peptide bond cleavage


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negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,051,901...106,056,137
Ensembl chr 1:106,051,901...106,056,137 		JBrowse link
G CDH1 cadherin 1 acts_upstream_of_or_within ISO (PMID:17344476) MGI PMID:17344476 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 involved_in ISO (PMID:22445366) UniProt PMID:22445366
G FMR1 Fragile X messenger ribonucleoprotein 1 ISO Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:116,249,079...116,287,008
Ensembl chr  X:116,249,142...116,321,439 		JBrowse link
G GAS1 growth arrest specific 1 involved_in ISO (PMID:21357679) UniProt PMID:21357679 NCBI chr 1:72,927,346...72,930,119
Ensembl chr 1:72,927,670...72,928,827 		JBrowse link
G GAS1 growth arrest specific 1 involved_in IEA Ensembl GO_REF:0000107
G GLG1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20530870) Ensembl
MGI		 PMID:20530870 GO_REF:0000107 NCBI chr 5:76,020,743...76,171,477
Ensembl chr 5:76,020,084...76,167,007 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23395675) Ensembl
MGI		 PMID:23395675 GO_REF:0000107 NCBI chr10:40,967,532...41,003,659
Ensembl chr10:40,896,669...41,034,113 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:107,486,399...107,490,151
Ensembl chr 1:107,486,438...107,489,222 		JBrowse link
G SNX12 sorting nexin 12 involved_in ISO (PMID:22709416) UniProt PMID:22709416 NCBI chr  X:55,441,271...55,450,767 JBrowse link
G TMEM98 transmembrane protein 98 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:40,130,421...40,144,120
Ensembl chr 9:40,128,885...40,144,181 		JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPB2 carboxypeptidase B2 ISO RGD PMID:23369837 RGD:7243115 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170 		JBrowse link
G CTSZ cathepsin Z involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:43,743,291...43,750,154
Ensembl chr24:43,743,294...43,754,424 		JBrowse link
G LOC119878767 glia-derived nexin involved_in IEA TreeGrafter GO_REF:0000118
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:45,876,076...45,883,777
Ensembl chr 9:45,877,495...45,883,036 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915 		JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr26:16,228,831...16,244,104
Ensembl chr26:16,234,710...16,240,012 		JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme involved_in ISO (PMID:11799113), (PMID:9130696) UniProt PMID:9130696 PMID:11799113 NCBI chr 3:53,357,491...53,368,285
Ensembl chr 3:53,358,045...53,365,423 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      primary metabolic process 9574
        protein metabolic process 4325
          proteolysis 1473
            protein processing 243
              negative regulation of protein processing 22
                negative regulation of peptide hormone processing 0
                negative regulation of plasminogen activation 7
                negative regulation of protein processing in phagocytic vesicle 0
                negative regulation of protein processing involved in protein targeting to mitochondrion 1
                zymogen inhibition + 1
Path 2
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of biological process 12078
        regulation of metabolic process 6412
          regulation of biosynthetic process 5261
            regulation of cellular biosynthetic process 5175
              regulation of macromolecule biosynthetic process 5079
                regulation of gene expression 4962
                  regulation of protein maturation 67
                    regulation of protein processing 63
                      negative regulation of protein processing 22
                        negative regulation of peptide hormone processing 0
                        negative regulation of plasminogen activation 7
                        negative regulation of protein processing in phagocytic vesicle 0
                        negative regulation of protein processing involved in protein targeting to mitochondrion 1
                        zymogen inhibition + 1
paths to the root