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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of phosphatase activity
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Accession:GO:0010923 term browser browse the term
Definition:Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.


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negative regulation of phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arfgef3 ARFGEF family member 3 JBrowse link NW_004936560 5,348,786 5,501,233 RGD:9068941
G Camsap3 calmodulin regulated spectrin associated protein family member 3 JBrowse link NW_004936588 4,660,664 4,669,836 RGD:9068941
G Ccdc8 coiled-coil domain containing 8 JBrowse link NW_004936664 429,733 432,673 RGD:9068941
G Cd2bp2 CD2 cytoplasmic tail binding protein 2 JBrowse link NW_004936501 12,823,781 12,828,460 RGD:9068941
G Cep192 centrosomal protein 192 JBrowse link NW_004936626 2,565,302 2,659,863 RGD:9068941
G Chp1 calcineurin like EF-hand protein 1 JBrowse link NW_004936471 4,611,980 4,660,320 RGD:9068941
G Cnst consortin, connexin sorting protein JBrowse link NW_004936526 4,399,886 4,497,185 RGD:9068941
G Csrnp2 cysteine and serine rich nuclear protein 2 JBrowse link NW_004936512 8,693,940 8,710,030 RGD:9068941
G Csrnp3 cysteine and serine rich nuclear protein 3 JBrowse link NW_004936469 13,628,830 13,808,970 RGD:9068941
G Dlg2 discs large MAGUK scaffold protein 2 JBrowse link NW_004936498 11,549,526 13,519,638 RGD:9068941
G Dlg3 discs large MAGUK scaffold protein 3 JBrowse link NW_004936762 982,331 1,038,486 RGD:9068941
G Elfn1 extracellular leucine rich repeat and fibronectin type III domain containing 1 JBrowse link NW_004936754 1,744,663 1,805,732 RGD:9068941
G Elfn2 extracellular leucine rich repeat and fibronectin type III domain containing 2 JBrowse link NW_004936492 3,624,400 3,641,118 RGD:9068941
G Ell elongation factor for RNA polymerase II JBrowse link NW_004936596 2,745,862 2,812,513 RGD:9068941
G Epm2a EPM2A glucan phosphatase, laforin JBrowse link NW_004936625 761,013 819,826 RGD:9068941
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 JBrowse link NW_004936472 11,891,234 12,100,202 RGD:9068941
G Fkbp15 FKBP prolyl isomerase 15 JBrowse link NW_004936559 364,810 422,338 RGD:9068941
G Gpatch2 G-patch domain containing 2 JBrowse link NW_004936628 1,006,216 1,181,124 RGD:9068941
G Grxcr1 glutaredoxin and cysteine rich domain containing 1 JBrowse link NW_004936482 9,981,410 10,087,222 RGD:9068941
G Knl1 kinetochore scaffold 1 JBrowse link NW_004936471 4,079,877 4,110,205 RGD:9068941
G Lmtk3 lemur tyrosine kinase 3 JBrowse link NW_004936664 2,579,204 2,598,189 RGD:9068941
G Marf1 meiosis regulator and mRNA stability factor 1 JBrowse link NW_004936501 3,151,030 3,189,656 RGD:9068941
G Mphosph10 M-phase phosphoprotein 10 JBrowse link NW_004936483 955,514 970,858 RGD:9068941
G Myo1d myosin ID JBrowse link NW_004936538 2,102,192 2,408,953 RGD:9068941
G Pcdh11x protocadherin 11 X-linked JBrowse link NW_004936649 1,843,290 1,893,991 RGD:9068941
G Pcif1 PDX1 C-terminal inhibiting factor 1 JBrowse link NW_004936514 7,090,367 7,103,124 RGD:9068941
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 JBrowse link NW_004936694 1,191,534 1,196,532 RGD:9068941
G Ppp1r26 protein phosphatase 1 regulatory subunit 26 JBrowse link NW_004936669 2,074,225 2,081,872 RGD:9068941
G Ppp1r27 protein phosphatase 1 regulatory subunit 27 JBrowse link NW_004936594 5,362,220 5,364,204 RGD:9068941
G Ppp1r35 protein phosphatase 1 regulatory subunit 35 JBrowse link NW_004936543 509,491 511,516 RGD:9068941
G Ppp1r36 protein phosphatase 1 regulatory subunit 36 JBrowse link NW_004936495 8,250,828 8,278,599 RGD:9068941
G Ppp1r37 protein phosphatase 1 regulatory subunit 37 JBrowse link NW_004936706 1,639,078 1,681,556 RGD:9068941
G Rbm26 RNA binding motif protein 26 JBrowse link NW_004936511 2,175,192 2,252,955 RGD:9068941
G Rimbp2 RIMS binding protein 2 JBrowse link NW_004936660 1,433,535 1,601,912 RGD:9068941
G Rrp1b ribosomal RNA processing 1B JBrowse link NW_004936500 574,445 600,555 RGD:9068941
G Sfi1 SFI1 centrin binding protein JBrowse link NW_004936755 645,907 716,890 RGD:9068941
G Sh2d4a SH2 domain containing 4A JBrowse link NW_004936555 3,572,723 3,634,484 RGD:9068941
G Sh3rf2 SH3 domain containing ring finger 2 JBrowse link NW_004936504 8,602,116 8,731,099 RGD:9068941
G Slc7a14 solute carrier family 7 member 14 JBrowse link NW_004936593 1,938,392 2,045,639 RGD:9068941
G Spocd1 SPOC domain containing 1 JBrowse link NW_004936474 14,894,564 14,918,088 RGD:9068941
G Spred1 sprouty related EVH1 domain containing 1 JBrowse link NW_004936471 1,952,532 2,039,561 RGD:9068941
G Sytl2 synaptotagmin like 2 JBrowse link NW_004936498 13,577,839 13,681,782 RGD:9068941
G Tmem132d transmembrane protein 132D JBrowse link NW_004936660 631,033 1,125,358 RGD:9068941
G Tmem225 transmembrane protein 225 JBrowse link NW_004936542 8,280,386 8,282,671 RGD:9068941
G Tsks testis specific serine kinase substrate JBrowse link NW_004936664 3,539,553 3,555,315 RGD:9068941
G Uri1 URI1 prefoldin like chaperone JBrowse link NW_004936570 5,379,253 5,419,595 RGD:9068941
G Wdr81 WD repeat domain 81 JBrowse link NW_004936538 7,856,263 7,868,249 RGD:9068941
G Wnk1 WNK lysine deficient protein kinase 1 JBrowse link NW_004936606 933,637 1,069,885 RGD:9068941
G Zcchc9 zinc finger CCHC-type containing 9 JBrowse link NW_004936469 617,320 625,738 RGD:9068941
G Zfyve1 zinc finger FYVE-type containing 1 JBrowse link NW_004936488 2,304,521 2,364,472 RGD:9068941
negative regulation of alkaline phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link NW_004936546 3,737,908 3,783,492 RGD:9068941
G Hpn hepsin JBrowse link NW_004936570 1,170,951 1,186,501 RGD:9068941
G LOC101975744 semaphorin-4D JBrowse link NW_004936780 317,926 350,113 RGD:9068941
G Tgfb2 transforming growth factor beta 2 JBrowse link NW_004936628 310,720 394,002 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link NW_004936785 358,128 406,751 RGD:9068941
G Mprip myosin phosphatase Rho interacting protein JBrowse link NW_004936741 757,618 864,051 RGD:9068941
G Nckap1l NCK associated protein 1 like JBrowse link NW_004936512 11,683,330 11,734,423 RGD:9068941
G Rock1 Rho associated coiled-coil containing protein kinase 1 JBrowse link NW_004936550 730,462 874,601 RGD:9068941
G Rock2 Rho associated coiled-coil containing protein kinase 2 JBrowse link NW_004936532 7,142,580 7,284,722 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bag4 BAG cochaperone 4 JBrowse link NW_004936710 1,551,729 1,575,393 RGD:9068941
negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bod1 biorientation of chromosomes in cell division 1 JBrowse link NW_004936609 2,034,271 2,096,274 RGD:9068941
G Cmya5 cardiomyopathy associated 5 JBrowse link NW_004936549 7,468,393 7,555,433 RGD:9068941
G Cry2 cryptochrome circadian regulator 2 JBrowse link NW_004936562 3,133,849 3,168,472 RGD:9068941
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link NW_004936485 17,305,376 17,311,797 RGD:9068941
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link NW_004936493 7,916,002 7,922,747 RGD:9068941
G Mastl microtubule associated serine/threonine kinase like JBrowse link NW_004936484 2,276,463 2,306,119 RGD:9068941
G Ppia peptidylprolyl isomerase A JBrowse link NW_004936478 19,669,727 19,673,355 RGD:9068941
G Ppp1r15a protein phosphatase 1 regulatory subunit 15A JBrowse link NW_004936664 2,910,609 2,914,205 RGD:9068941
G Ppp1r1b protein phosphatase 1 regulatory inhibitor subunit 1B JBrowse link NW_004936490 14,822,246 14,831,337 RGD:9068941
G Ppp1r9b protein phosphatase 1 regulatory subunit 9B JBrowse link NW_004936490 11,497,389 11,514,191 RGD:9068941
G Ppp4r4 protein phosphatase 4 regulatory subunit 4 JBrowse link NW_004936733 2,007,843 2,119,766 RGD:9068941
G Ptpa protein phosphatase 2 phosphatase activator JBrowse link NW_004936487 16,536,740 16,564,087 RGD:9068941
G Rgn regucalcin JBrowse link NW_004936502 12,872,938 12,891,270 RGD:9068941
G Styxl1 serine/threonine/tyrosine interacting like 1 JBrowse link NW_004936543 2,208,669 2,269,264 RGD:9068941
G Tiprl TOR signaling pathway regulator JBrowse link NW_004936481 18,050,020 18,072,906 RGD:9068941
negative regulation of protein serine/threonine phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppp1r14d protein phosphatase 1 regulatory inhibitor subunit 14D JBrowse link NW_004936471 4,208,747 4,230,526 RGD:9068941
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnai2 G protein subunit alpha i2 JBrowse link NW_004936529 1,779,582 1,801,251 RGD:9068941
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase JBrowse link NW_004936469 57,615,755 57,875,156 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11930
    biological regulation 8730
      regulation of molecular function 2142
        regulation of catalytic activity 1498
          negative regulation of catalytic activity 532
            negative regulation of hydrolase activity 265
              negative regulation of phosphatase activity 79
                negative regulation of alkaline phosphatase activity 5
                negative regulation of phosphatidate phosphatase activity 0
                negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity 1
                negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 0
                negative regulation of phosphoprotein phosphatase activity + 24
Path 2
Term Annotations click to browse term
  biological_process 11930
    biological regulation 8730
      regulation of biological process 8292
        regulation of metabolic process 5068
          regulation of cellular metabolic process 4544
            regulation of phosphorus metabolic process 1540
              regulation of phosphate metabolic process 1539
                regulation of dephosphorylation 157
                  regulation of phosphatase activity 119
                    negative regulation of phosphatase activity 79
                      negative regulation of alkaline phosphatase activity 5
                      negative regulation of phosphatidate phosphatase activity 0
                      negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity 1
                      negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 0
                      negative regulation of phosphoprotein phosphatase activity + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.