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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of phosphatase activity
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Accession:GO:0010923 term browser browse the term
Definition:Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.


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negative regulation of phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07051376.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 3:11,781,295...11,790,073 JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:10593895)
UniProt
RGD
PMID:10593895 GO_REF:0000024 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin involved_in ISO (PMID:18617530) RGD PMID:18617530 NCBI chr 1:5,727,111...5,845,338
Ensembl chr 1:5,727,066...5,920,555
JBrowse link
G Ppp1r35 protein phosphatase 1, regulatory subunit 35 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:18,915,909...18,919,253 JBrowse link
G Ppp1r36 protein phosphatase 1, regulatory subunit 36 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:95,138,526...95,159,102
Ensembl chr 6:95,139,007...95,159,102
JBrowse link
G Tmem225 transmembrane protein 225 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:40,497,483...40,500,041
Ensembl chr 8:40,497,483...40,500,041
JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in IBA
ISO
PMID:21873635
(PMID:17936702)
RGD PMID:17936702 PMID:21873635 RGD:13792537 NCBI chr 1:90,646,392...90,704,811
Ensembl chr 1:90,646,393...90,709,026
JBrowse link
negative regulation of alkaline phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IDA RGD PMID:12193573 RGD:625678 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Hpn hepsin acts_upstream_of_or_within ISO MGI:3575149 (MGI:5437809|PMID:22912808) RGD PMID:22912808 MGI:5437809 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Sema4d semaphorin 4D involved_in IBA
ISO
PMID:21873635
(MGI:5297297|PMID:22019888)
(PMID:22019888)
RGD PMID:22019888 PMID:21873635 MGI:5297297, RGD:13792537 NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:18358889)
UniProt
RGD
PMID:18358889 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (MGI:5285024|PMID:21689636) RGD PMID:21689636 MGI:5285024 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA
ISO
GO_REF:0000107
(PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Mprip myosin phosphatase Rho interacting protein IMP RGD PMID:17661354 RGD:9685557 NCBI chr10:44,453,929...44,569,442
Ensembl chr10:44,453,929...44,569,118
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO
GO_REF:0000024
(PMID:16417406)
UniProt
RGD
PMID:16417406 GO_REF:0000024 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
UniProtKB:O75116 (PMID:25816133)
GO_REF:0000107
RGD
Ensembl
PMID:25816133 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) RGD PMID:21712384 MGI:5292318 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in IBA
ISO
PMID:21873635
(PMID:24157919)
RGD PMID:24157919 PMID:21873635 RGD:13792537 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:69,108,483...69,163,255
Ensembl chr14:69,108,491...69,162,490
JBrowse link
G Cmya5 cardiomyopathy associated 5 acts_upstream_of_or_within ISO (MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:5056263 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364
JBrowse link
G Cry2 cryptochrome circadian regulator 2 involved_in ISO
IEA
(PMID:9383998)
GO_REF:0000107
RGD
Ensembl
PMID:9383998 GO_REF:0000107 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:7592869) RGD PMID:7592869 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (PMID:7592869) RGD PMID:7592869 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like involved_in ISO (PMID:20538976) RGD PMID:20538976 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
JBrowse link
G Ppia peptidylprolyl isomerase A IDA RGD PMID:19832699 RGD:7247324 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:1,601,350...1,604,857
Ensembl chr20:1,601,346...1,604,846
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:11564868) RGD PMID:11564868 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B involved_in ISO (PMID:10807923) RGD PMID:10807923 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IDA
IMP
RGD PMID:12016225 PMID:10585469 RGD:625568, RGD:9999389 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083
JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:18715871)
RGD PMID:18715871 PMID:21873635 RGD:13792537 NCBI chr 6:122,663,172...122,753,988
Ensembl chr 6:122,663,344...122,753,384
JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator involved_in ISO (PMID:16916641) RGD PMID:16916641 NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549
JBrowse link
G Rgn regucalcin IMP RGD PMID:10922512 RGD:9590172 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO (PMID:24709986) RGD PMID:24709986 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752
JBrowse link
G Tiprl TOR signaling pathway regulator involved_in ISO (PMID:17384681) RGD PMID:17384681 NCBI chr13:77,527,176...77,552,026
Ensembl chr13:77,527,176...77,552,074
JBrowse link
negative regulation of protein serine/threonine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r14d protein phosphatase 1, regulatory (inhibitor) subunit 14D involved_in ISO
ISS
(PMID:12974676)
GO_REF:0000024
RGD
UniProt
PMID:12974676 GO_REF:0000024 NCBI chr 3:106,205,043...106,219,290
Ensembl chr 3:106,205,046...106,219,649
JBrowse link
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11500506 RGD:13508599 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase involved_in ISO (PMID:24846175) RGD PMID:24846175 NCBI chr13:38,675,776...38,959,697
Ensembl chr13:38,676,119...38,959,513
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of molecular function 3071
        regulation of catalytic activity 2373
          negative regulation of catalytic activity 800
            negative regulation of hydrolase activity 414
              negative regulation of phosphatase activity 39
                negative regulation of alkaline phosphatase activity 5
                negative regulation of phosphatidate phosphatase activity 1
                negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity 1
                negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 0
                negative regulation of phosphoprotein phosphatase activity + 26
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of metabolic process 6740
          regulation of cellular metabolic process 5897
            regulation of phosphorus metabolic process 1476
              regulation of phosphate metabolic process 1475
                regulation of dephosphorylation 134
                  regulation of phosphatase activity 87
                    negative regulation of phosphatase activity 39
                      negative regulation of alkaline phosphatase activity 5
                      negative regulation of phosphatidate phosphatase activity 1
                      negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity 1
                      negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 0
                      negative regulation of phosphoprotein phosphatase activity + 26
paths to the root