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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
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Accession:GO:0010880 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.


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regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm2 calmodulin 2 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936508:5,207,909...5,223,780 JBrowse link
G Calm3 calmodulin 3 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936664:471,446...480,858 JBrowse link
G Camk2d calcium/calmodulin dependent protein kinase II delta ISO PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chrNW_004936563:4,226,412...4,526,139 JBrowse link
G Casq1 calsequestrin 1 ISO (MGI:MGI:2449410|PMID:12419813)
(MGI:MGI:3814667|PMID:17627988)
MGI PMID:12419813, PMID:17627988 MGI:MGI:2449410, MGI:MGI:3814667 NCBI chrNW_004936740:430,367...442,468 JBrowse link
G Casq2 calsequestrin 2 ISO (PMID:15041652)
(MGI:MGI:3689635|PMID:16932808)
BHF-UCL
UniProtKB
PMID:15041652, PMID:16932808 MGI:MGI:3689635 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 ISO (MGI:MGI:5694290|PMID:26102480) MGI PMID:26102480 MGI:MGI:5694290 NCBI chrNW_004936496:12,381,225...12,505,121 JBrowse link
G Clic2 chloride intracellular channel 2 ISO (PMID:15147738), (PMID:15916532) BHF-UCL PMID:15147738, PMID:15916532 NCBI chrNW_004936927:514,989...543,691 JBrowse link
G Dhrs7c dehydrogenase/reductase 7C ISO (MGI:MGI:5306721|PMID:21995425) MGI PMID:21995425 MGI:MGI:5306721 NCBI chrNW_004936595:2,732,106...2,769,782 JBrowse link
G Dmd dystrophin ISO (MGI:MGI:4420848|PMID:20080623), (MGI:MGI:5487906|PMID:23263329) BHF-UCL PMID:20080623, PMID:23263329 MGI:MGI:4420848, MGI:MGI:5487906 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO (PMID:20431056)
(MGI:MGI:3639647|PMID:16672364)
(MGI:MGI:3028710|PMID:14592808), (MGI:MGI:5007884|PMID:19578067)
BHF-UCL
MGI
PMID:14592808, PMID:16672364, PMID:19578067, PMID:20431056 MGI:MGI:3028710, MGI:MGI:3639647, MGI:MGI:5007884 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chrNW_004936600:1,932,152...1,943,342 JBrowse link
G Hrc histidine rich calcium binding protein ISO (PMID:24125847) BHF-UCL PMID:24125847 NCBI chrNW_004936664:3,088,072...3,092,034 JBrowse link
G LOC101967074 calmodulin ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936488:17,580,425...17,588,480 JBrowse link
G Mettl21c methyltransferase like 21C ISO (MGI:MGI:5781029|PMID:24677265) MGI PMID:24677265 MGI:MGI:5781029 NCBI chrNW_004936472:8,355,075...8,366,229 JBrowse link
G Nol3 nucleolar protein 3 ISO PMID:23382383 UniProt PMID:23382383 RGD:10047354 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Pde4d phosphodiesterase 4D ISO (MGI:MGI:3690823|PMID:16213210) BHF-UCL PMID:16213210 MGI:MGI:3690823 NCBI chrNW_004936480:8,123,437...9,235,586 JBrowse link
G Pln phospholamban ISO (MGI:MGI:3655341|PMID:9118481) MGI PMID:9118481 MGI:MGI:3655341 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Trdn triadin ISO (PMID:15041652) BHF-UCL
RGD
PMID:15041652, PMID:17569730 RGD:2314601 NCBI chrNW_004936802:389,653...637,372 JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 ISO (MGI:MGI:5427070|PMID:21859974), (MGI:MGI:5430893|PMID:17178715)
(PMID:17178715)
BHF-UCL PMID:17178715, PMID:21859974 MGI:MGI:5427070, MGI:MGI:5430893 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Asph aspartate beta-hydroxylase ISO (PMID:17400717) BHF-UCL PMID:17400717 NCBI chrNW_004936496:11,604,992...11,815,680 JBrowse link
G Casq2 calsequestrin 2 ISO (MGI:MGI:1202079|PMID:9525981)
PMID:17569730
(MGI:MGI:3689635|PMID:16932808)
(PMID:16601229), (PMID:16908766)
MGI
BHF-UCL
UniProtKB
PMID:9525981, PMID:16601229, PMID:16908766, PMID:16932808, PMID:17569730 MGI:MGI:1202079, MGI:MGI:3689635, RGD:2314601 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Dmd dystrophin ISO (MGI:MGI:4420848|PMID:20080623) BHF-UCL PMID:20080623 MGI:MGI:4420848 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO (MGI:MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:MGI:3621834 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Pln phospholamban ISO (MGI:MGI:82999|PMID:8831698) MGI PMID:8831698 MGI:MGI:82999 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Ryr2 ryanodine receptor 2 ISO (MGI:MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:MGI:3621834 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chrNW_004936508:10,894,918...11,256,084 JBrowse link
G Tmem38a transmembrane protein 38A ISO (MGI:MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:MGI:3715564 NCBI chrNW_004936596:3,965,220...3,984,120 JBrowse link
G Tmem38b transmembrane protein 38B ISO (MGI:MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:MGI:3715564 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 ISO (MGI:MGI:5306707|PMID:22049211)
(MGI:MGI:3814667|PMID:17627988)
UniProtKB
MGI
PMID:17627988, PMID:22049211 MGI:MGI:3814667, MGI:MGI:5306707 NCBI chrNW_004936740:430,367...442,468 JBrowse link
G Dmd dystrophin ISO (MGI:MGI:3837615|PMID:19198614) BHF-UCL PMID:19198614 MGI:MGI:3837615 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    biological regulation 8793
      regulation of biological quality 3394
        regulation of calcium ion transport into cytosol 107
          regulation of release of sequestered calcium ion into cytosol 80
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 24
              regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 10
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion + 2
Path 2
Term Annotations click to browse term
  biological_process 12001
    biological regulation 8793
      regulation of biological quality 3394
        homeostatic process 1727
          chemical homeostasis 1063
            ion homeostasis 692
              cellular ion homeostasis 548
                cellular cation homeostasis 536
                  cellular metal ion homeostasis 488
                    cellular calcium ion homeostasis 399
                      regulation of cytosolic calcium ion concentration 307
                        positive regulation of cytosolic calcium ion concentration 270
                          calcium ion transport into cytosol 156
                            calcium ion transmembrane import into cytosol 133
                              release of sequestered calcium ion into cytosol 108
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 26
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 24
                                      regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 10
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.