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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
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Accession:GO:0010880 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.


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regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 IC PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Calm1 calmodulin 1 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IDA PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Casq1 calsequestrin 1 ISO MGI:MGI:3530841 (MGI:MGI:2449410|PMID:12419813), (MGI:MGI:3814667|PMID:17627988) RGD PMID:12419813, PMID:17627988 MGI:MGI:2449410, MGI:MGI:3814667 NCBI chr13:90,592,676...90,602,365
Ensembl chr13:90,592,681...90,602,365
JBrowse link
G Casq2 calsequestrin 2 ISO (MGI:MGI:3689635|PMID:16932808)
(PMID:15041652)
RGD PMID:15041652, PMID:16932808 MGI:MGI:3689635 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 ISO MGI:MGI:2176467|MGI:MGI:4433295 (MGI:MGI:5694290|PMID:26102480) RGD PMID:26102480 MGI:MGI:5694290 NCBI chr 5:21,769,087...21,952,036
Ensembl chr 5:21,830,882...21,950,696
JBrowse link
G Clic2 chloride intracellular channel 2 ISO (PMID:15147738), (PMID:15916532) RGD PMID:15147738, PMID:15916532 NCBI chr20:295,338...310,363
Ensembl chr20:295,250...310,380
JBrowse link
G Dhrs7c dehydrogenase/reductase 7C ISO
IBA
(MGI:MGI:5306721|PMID:21995425)
PMID:21873635
RGD PMID:21995425, PMID:21873635 MGI:MGI:5306721, RGD:13792537 NCBI chr10:54,352,270...54,370,653
Ensembl chr10:54,352,270...54,370,653
JBrowse link
G Dmd dystrophin ISO (MGI:MGI:4420848|PMID:20080623), (MGI:MGI:5487906|PMID:23263329) RGD PMID:20080623, PMID:23263329 MGI:MGI:4420848, MGI:MGI:5487906 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO (PMID:20431056)
MGI:MGI:2182644|MGI:MGI:3623214 (MGI:MGI:3028710|PMID:14592808), (MGI:MGI:3639647|PMID:16672364), (MGI:MGI:5007884|PMID:19578067)
RGD PMID:14592808, PMID:16672364, PMID:19578067, PMID:20431056 MGI:MGI:3028710, MGI:MGI:3639647, MGI:MGI:5007884 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO
IEA
(PMID:17023043)
GO_REF:0000107
RGD
Ensembl
PMID:17023043 GO_REF:0000107 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:210,720,719...210,726,179
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO
IEA
(PMID:11035031)
GO_REF:0000107
RGD
Ensembl
PMID:11035031 GO_REF:0000107 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Hrc histidine rich calcium binding protein ISO UniProtKB:B9EIW1 (PMID:24125847) RGD PMID:24125847 NCBI chr 1:101,324,788...101,328,391
Ensembl chr 1:101,324,652...101,328,435
JBrowse link
G Mettl21c methyltransferase like 21C ISO (MGI:MGI:5781029|PMID:24677265) RGD PMID:24677265 MGI:MGI:5781029 NCBI chr 9:50,750,971...50,762,082
Ensembl chr 9:50,750,971...50,762,082
JBrowse link
G Nol3 nucleolar protein 3 IMP PMID:23382383 UniProt PMID:23382383 RGD:10047354 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Pde4d phosphodiesterase 4D ISO
IEA
(MGI:MGI:3690823|PMID:16213210)
GO_REF:0000107
RGD
Ensembl
PMID:16213210 GO_REF:0000107, MGI:MGI:3690823 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Pln phospholamban ISO MGI:MGI:2158357 (MGI:MGI:3655341|PMID:9118481) RGD PMID:9118481 MGI:MGI:3655341 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Trdn triadin IMP
IBA
ISO
PMID:21873635
(PMID:15041652)
RGD PMID:15041652, PMID:17569730, PMID:21873635 RGD:2314601, RGD:13792537 NCBI chr 1:25,403,390...25,787,664
Ensembl chr 1:25,403,390...25,839,345
JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 ISO UniProtKB:Q8C8R3 (PMID:17178715)
(MGI:MGI:5427070|PMID:21859974), (MGI:MGI:5430893|PMID:17178715)
RGD PMID:17178715, PMID:21859974 MGI:MGI:5427070, MGI:MGI:5430893 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Asph aspartate-beta-hydroxylase ISO (PMID:17400717) RGD PMID:17400717 NCBI chr 5:22,577,680...22,799,333
Ensembl chr 5:22,577,675...22,799,349
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IC PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Casq2 calsequestrin 2 IMP
IBA
ISO
IEA
PMID:17569730
PMID:21873635
(MGI:MGI:1202079|PMID:9525981), (MGI:MGI:3689635|PMID:16932808)
(PMID:16601229), (PMID:16908766)
GO_REF:0000107
RGD
Ensembl
PMID:9525981, PMID:16601229, PMID:16908766, PMID:16932808, PMID:17569730, PMID:21873635 GO_REF:0000107, MGI:MGI:1202079, MGI:MGI:3689635, RGD:2314601, RGD:13792537 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Dmd dystrophin ISO (MGI:MGI:4420848|PMID:20080623) RGD PMID:20080623 MGI:MGI:4420848 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO
IBA
(MGI:MGI:3621834|PMID:12837242)
PMID:21873635
RGD PMID:12837242, PMID:21873635 MGI:MGI:3621834, RGD:13792537 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Pln phospholamban ISO MGI:MGI:2158357 (MGI:MGI:82999|PMID:8831698) RGD PMID:8831698 MGI:MGI:82999 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Ryr2 ryanodine receptor 2 ISO
IEA
UniProtKB:Q9Z2I2 (MGI:MGI:3621834|PMID:12837242)
GO_REF:0000107
RGD
Ensembl
PMID:12837242 GO_REF:0000107, MGI:MGI:3621834 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IDA PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Tmem38a transmembrane protein 38a ISO
IEA
MGI:MGI:1098718 (MGI:MGI:3715564|PMID:17611541)
GO_REF:0000107
RGD
Ensembl
PMID:17611541 GO_REF:0000107, MGI:MGI:3715564 NCBI chr16:18,960,197...18,974,942
Ensembl chr16:18,959,315...18,974,770
JBrowse link
G Tmem38b transmembrane protein 38B ISO MGI:MGI:1921416 (MGI:MGI:3715564|PMID:17611541) RGD PMID:17611541 MGI:MGI:3715564 NCBI chr 5:70,639,156...70,675,055
Ensembl chr 5:70,639,156...70,675,054
JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 ISS
ISO
IBA
GO_REF:0000024
MGI:MGI:3530841 (MGI:MGI:3814667|PMID:17627988), (MGI:MGI:5306707|PMID:22049211)
PMID:21873635
UniProt
RGD
PMID:17627988, PMID:22049211, PMID:21873635 GO_REF:0000024, MGI:MGI:3814667, MGI:MGI:5306707, RGD:13792537 NCBI chr13:90,592,676...90,602,365
Ensembl chr13:90,592,681...90,602,365
JBrowse link
G Dmd dystrophin ISO (MGI:MGI:3837615|PMID:19198614) RGD PMID:19198614 MGI:MGI:3837615 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological quality 4283
        regulation of calcium ion transport into cytosol 117
          regulation of release of sequestered calcium ion into cytosol 88
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 28
              regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 12
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion + 2
Path 2
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological quality 4283
        homeostatic process 2090
          chemical homeostasis 1328
            ion homeostasis 882
              cellular ion homeostasis 724
                cellular cation homeostasis 711
                  cellular metal ion homeostasis 644
                    cellular calcium ion homeostasis 512
                      regulation of cytosolic calcium ion concentration 409
                        positive regulation of cytosolic calcium ion concentration 360
                          calcium ion transport into cytosol 176
                            calcium ion transmembrane import into cytosol 152
                              release of sequestered calcium ion into cytosol 127
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 32
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 31
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 28
                                      regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 12
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.