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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
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Accession:GO:0010880 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.


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regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CALM2 calmodulin 2 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chr2A:47,274,722...47,290,861 JBrowse link
G CALM3 calmodulin 3 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387
JBrowse link
G CASQ1 calsequestrin 1 ISO (MGI:MGI:2449410|PMID:12419813)
(MGI:MGI:3814667|PMID:17627988)
MGI PMID:12419813, PMID:17627988 MGI:MGI:2449410, MGI:MGI:3814667 NCBI chr 1:135,544,249...135,555,545
Ensembl chr 1:139,465,605...139,476,969
JBrowse link
G CASQ2 calsequestrin 2 ISO (PMID:15041652)
(MGI:MGI:3689635|PMID:16932808)
BHF-UCL
UniProtKB
PMID:15041652, PMID:16932808 MGI:MGI:3689635 NCBI chr 1:86,795,392...86,864,196
Ensembl chr 1:121,844,097...121,913,311
JBrowse link
G CHD7 chromodomain helicase DNA binding protein 7 ISO (MGI:MGI:5694290|PMID:26102480) MGI PMID:26102480 MGI:MGI:5694290 NCBI chr 8:57,091,002...57,282,471
Ensembl chr 8:58,816,840...58,945,186
JBrowse link
G CLIC2 chloride intracellular channel 2 ISO (PMID:15147738), (PMID:15916532) BHF-UCL PMID:15147738, PMID:15916532 NCBI chr  X:144,742,839...144,851,524
Ensembl chr  X:154,581,649...154,641,515
JBrowse link
G DHRS7C dehydrogenase/reductase 7C ISO (MGI:MGI:5306721|PMID:21995425) MGI PMID:21995425 MGI:MGI:5306721 NCBI chr17:41,864,761...41,884,938
Ensembl chr17:46,608,656...46,628,709
JBrowse link
G DMD dystrophin ISO (MGI:MGI:4420848|PMID:20080623), (MGI:MGI:5487906|PMID:23263329) BHF-UCL PMID:20080623, PMID:23263329 MGI:MGI:4420848, MGI:MGI:5487906 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B ISO (PMID:20431056)
(MGI:MGI:3028710|PMID:14592808), (MGI:MGI:5007884|PMID:19578067)
(MGI:MGI:3639647|PMID:16672364)
BHF-UCL
MGI
PMID:14592808, PMID:16672364, PMID:19578067, PMID:20431056 MGI:MGI:3028710, MGI:MGI:3639647, MGI:MGI:5007884 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082
JBrowse link
G GSTM2 glutathione S-transferase mu 2 ISO (PMID:17023043) BHF-UCL PMID:17023043 NCBI chr 1:112,043,201...112,050,810 JBrowse link
G GSTO1 glutathione S-transferase omega 1 ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chr10:100,853,682...100,866,892
Ensembl chr10:104,313,024...104,325,733
JBrowse link
G HRC histidine rich calcium binding protein ISO (PMID:24125847) BHF-UCL PMID:24125847 NCBI chr19:46,162,231...46,166,606
Ensembl chr19:55,089,384...55,093,463
JBrowse link
G METTL21C methyltransferase like 21C ISO (MGI:MGI:5781029|PMID:24677265) MGI PMID:24677265 MGI:MGI:5781029 NCBI chr13:83,845,572...83,855,215
Ensembl chr13:102,981,536...102,990,336
JBrowse link
G NOL3 nucleolar protein 3 ISO PMID:23382383 UniProt PMID:23382383 RGD:10047354 NCBI chr16:47,516,156...47,521,441 JBrowse link
G PDE4D phosphodiesterase 4D ISO (MGI:MGI:3690823|PMID:16213210) BHF-UCL PMID:16213210 MGI:MGI:3690823 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111
JBrowse link
G PLN phospholamban ISO (MGI:MGI:3655341|PMID:9118481) MGI PMID:9118481 MGI:MGI:3655341 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668
JBrowse link
G TRDN triadin ISO (PMID:15041652) RGD
BHF-UCL
PMID:15041652, PMID:17569730 RGD:2314601 NCBI chr 6:121,010,234...121,424,644
Ensembl chr 6:125,134,433...125,546,537
JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 ISO (MGI:MGI:5427070|PMID:21859974), (MGI:MGI:5430893|PMID:17178715)
(PMID:17178715)
BHF-UCL PMID:17178715, PMID:21859974 MGI:MGI:5427070, MGI:MGI:5430893 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905
JBrowse link
G ASPH aspartate beta-hydroxylase ISO (PMID:17400717) BHF-UCL PMID:17400717 NCBI chr 8:57,921,580...58,134,778
Ensembl chr 8:59,629,707...59,843,658
JBrowse link
G CASQ2 calsequestrin 2 ISO PMID:17569730
(PMID:16601229), (PMID:16908766)
(MGI:MGI:1202079|PMID:9525981)
(MGI:MGI:3689635|PMID:16932808)
BHF-UCL
MGI
UniProtKB
PMID:9525981, PMID:16601229, PMID:16908766, PMID:16932808, PMID:17569730 MGI:MGI:1202079, MGI:MGI:3689635, RGD:2314601 NCBI chr 1:86,795,392...86,864,196
Ensembl chr 1:121,844,097...121,913,311
JBrowse link
G DMD dystrophin ISO (MGI:MGI:4420848|PMID:20080623) BHF-UCL PMID:20080623 MGI:MGI:4420848 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B ISO (MGI:MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:MGI:3621834 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082
JBrowse link
G PLN phospholamban ISO (MGI:MGI:82999|PMID:8831698) MGI PMID:8831698 MGI:MGI:82999 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668
JBrowse link
G RYR2 ryanodine receptor 2 ISO (MGI:MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:MGI:3621834 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509
JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038
JBrowse link
G TMEM38A transmembrane protein 38A ISO (MGI:MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:MGI:3715564 NCBI chr19:16,150,715...16,179,256
Ensembl chr19:17,129,842...17,159,002
JBrowse link
G TMEM38B transmembrane protein 38B ISO (MGI:MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:MGI:3715564 NCBI chr 9:76,854,177...76,938,334
Ensembl chr 9:104,980,935...105,128,988
JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASQ1 calsequestrin 1 ISO (MGI:MGI:5306707|PMID:22049211)
(MGI:MGI:3814667|PMID:17627988)
UniProtKB
MGI
PMID:17627988, PMID:22049211 MGI:MGI:3814667, MGI:MGI:5306707 NCBI chr 1:135,544,249...135,555,545
Ensembl chr 1:139,465,605...139,476,969
JBrowse link
G DMD dystrophin ISO (MGI:MGI:3837615|PMID:19198614) BHF-UCL PMID:19198614 MGI:MGI:3837615 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12564
    biological regulation 9168
      regulation of biological quality 3506
        regulation of calcium ion transport into cytosol 116
          regulation of release of sequestered calcium ion into cytosol 87
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25
              regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 10
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion + 2
Path 2
Term Annotations click to browse term
  biological_process 12564
    biological regulation 9168
      regulation of biological quality 3506
        homeostatic process 1794
          chemical homeostasis 1105
            ion homeostasis 723
              cellular ion homeostasis 575
                cellular cation homeostasis 563
                  cellular metal ion homeostasis 514
                    cellular calcium ion homeostasis 423
                      regulation of cytosolic calcium ion concentration 328
                        positive regulation of cytosolic calcium ion concentration 290
                          calcium ion transport into cytosol 165
                            calcium ion transmembrane import into cytosol 140
                              release of sequestered calcium ion into cytosol 116
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 28
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 27
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25
                                      regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 10
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.