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ONTOLOGY REPORT - ANNOTATIONS


Term:cholesterol storage
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Accession:GO:0010878 term browser browse the term
Definition:The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Synonyms:narrow_synonym: cholesterol sequestration;   sequestration of cholesterol


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cholesterol storage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOAT1 sterol O-acyltransferase 1 involved_in IMP (PMID:8407899) BHF-UCL PMID:8407899 NCBI chr 1:179,293,719...179,358,680
Ensembl chr 1:179,293,714...179,358,680
JBrowse link
cholesterol transport involved in cholesterol storage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STARD4 StAR related lipid transfer domain containing 4 involved_in IDA
IBA
(PMID:18403318)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:18403318 PMID:21873635 NCBI chr 5:111,491,422...111,512,567
Ensembl chr 5:111,496,033...111,512,590
JBrowse link
negative regulation of cholesterol storage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in TAS (PMID:18490524) BHF-UCL PMID:18490524 NCBI chr 9:104,781,006...104,928,232
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in TAS (PMID:18490524) BHF-UCL PMID:18490524 NCBI chr21:42,199,689...42,304,387
Ensembl chr21:42,199,689...42,297,244
JBrowse link
G CES1 carboxylesterase 1 involved_in IMP (PMID:16971496), (PMID:18599737), (PMID:18762277) UniProt PMID:16971496 PMID:18599737 PMID:18762277 NCBI chr16:55,802,851...55,833,127
Ensembl chr16:55,802,851...55,833,337
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IMP (PMID:17693624) BHF-UCL PMID:17693624 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA
ISO
IMP
(MGI:3720271|PMID:17657314)
(PMID:17693624)
Ensembl
BHF-UCL
BHF-UCL
PMID:17657314 PMID:17693624 GO_REF:0000107 MGI:3720271 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in IDA
IBA
(PMID:19114110)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:19114110 PMID:21873635 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:35,342,558...35,428,180
Ensembl chr 6:35,342,558...35,428,191
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in IDA
IBA
(PMID:19114110)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:19114110 PMID:21873635 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G TTC39B tetratricopeptide repeat domain 39B involved_in IBA
ISO
ISS
(PMID:21873635)
(MGI:5800596|PMID:27383786)
GO_Central
UniProt
UniProt
PMID:21873635 PMID:27383786 GO_REF:0000024 MGI:5800596 NCBI chr 9:15,163,622...15,307,360
Ensembl chr 9:15,163,622...15,307,360
JBrowse link
positive regulation of cholesterol storage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOB apolipoprotein B involved_in IDA (PMID:19114110) BHF-UCL PMID:19114110 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G CD36 CD36 molecule involved_in IEA
ISO
(MGI:2447499|PMID:12376530) Ensembl
BHF-UCL
PMID:12376530 GO_REF:0000107 MGI:2447499 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G EHD1 EH domain containing 1 involved_in IEA
ISO
ISS
(MGI:3711403|PMID:17451652) Ensembl
BHF-UCL
BHF-UCL
PMID:17451652 GO_REF:0000024 GO_REF:0000107 MGI:3711403 NCBI chr11:64,851,642...64,879,693
Ensembl chr11:64,851,642...64,888,296
JBrowse link
G LPL lipoprotein lipase involved_in IMP (PMID:12573449) BHF-UCL PMID:12573449 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G MSR1 macrophage scavenger receptor 1 involved_in IBA
ISO
IEA
ISS
(PMID:21873635)
(MGI:2447499|PMID:12376530)
GO_Central
BHF-UCL
Ensembl
BHF-UCL
PMID:12376530 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:2447499 NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490
JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IDA (PMID:9211901) BHF-UCL PMID:9211901 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 acts_upstream_of
involved_in
IDA
IBA
(PMID:15358760)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:15358760 PMID:21873635 NCBI chr22:41,833,105...41,907,308
Ensembl chr22:41,833,079...41,907,307
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18683
    localization 7251
      maintenance of location 364
        lipid storage 87
          cholesterol storage 18
            cholesterol transport involved in cholesterol storage 1
            negative regulation of cholesterol storage 9
            positive regulation of cholesterol storage 7
            regulation of cholesterol storage + 16
Path 2
Term Annotations click to browse term
  biological_process 18683
    localization 7251
      macromolecule localization 3476
        lipid localization 551
          lipid storage 87
            cholesterol storage 18
              cholesterol transport involved in cholesterol storage 1
              negative regulation of cholesterol storage 9
              positive regulation of cholesterol storage 7
              regulation of cholesterol storage + 16
paths to the root