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ONTOLOGY REPORT - ANNOTATIONS


Term:cholesterol storage
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Accession:GO:0010878 term browser browse the term
Definition:The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Synonyms:narrow_synonym: cholesterol sequestration;   sequestration of cholesterol


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cholesterol storage term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Soat1 sterol O-acyltransferase 1 ISO
IEA
(PMID:8407899)
GO_REF:0000107
RGD
Ensembl
PMID:8407899 GO_REF:0000107 NCBI chr13:74,035,258...74,077,759
Ensembl chr13:74,035,080...74,077,783
JBrowse link
cholesterol transport involved in cholesterol storage term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stard4 StAR-related lipid transfer domain containing 4 ISO
IBA
(PMID:18403318)
PMID:21873635
RGD PMID:18403318, PMID:21873635 RGD:13792537 NCBI chr18:25,982,210...25,997,555
Ensembl chr18:25,984,638...25,997,555
JBrowse link
negative regulation of cholesterol storage term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D ISO (PMID:16971496), (PMID:18599737), (PMID:18762277) RGD PMID:16971496, PMID:18599737, PMID:18762277 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 ISO (PMID:17693624) RGD PMID:17693624 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 ISO (PMID:17693624)
UniProtKB:P08226 (MGI:3720271|PMID:17657314)
RGD PMID:17657314, PMID:17693624 MGI:3720271 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO
IBA
(PMID:19114110)
PMID:21873635
RGD PMID:19114110, PMID:21873635 RGD:13792537 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO
IBA
(PMID:19114110)
PMID:21873635
RGD PMID:19114110, PMID:21873635 RGD:13792537 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B ISS
ISO
IBA
GO_REF:0000024
(MGI:5800596|PMID:27383786)
PMID:21873635
UniProt
RGD
PMID:27383786, PMID:21873635 GO_REF:0000024, MGI:5800596, RGD:13792537 NCBI chr 5:101,304,982...101,405,689
Ensembl chr 5:101,304,982...101,405,656
JBrowse link
G Ttc39d tetratricopeptide repeat domain 39D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:2,886,764...2,895,118
Ensembl chr 6:2,886,764...2,895,118
JBrowse link
positive regulation of cholesterol storage term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apob apolipoprotein B ISO (PMID:19114110) RGD PMID:19114110 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Cd36 CD36 molecule ISO (MGI:2447499|PMID:12376530) RGD PMID:12376530 MGI:2447499 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Ehd1 EH-domain containing 1 ISO (MGI:3711403|PMID:17451652) RGD PMID:17451652 MGI:3711403 NCBI chr 1:221,644,867...221,667,242
Ensembl chr 1:221,644,867...221,667,239
JBrowse link
G Lpl lipoprotein lipase ISO (PMID:12573449) RGD PMID:12573449 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Msr1 macrophage scavenger receptor 1 IBA
ISO
PMID:21873635
(MGI:2447499|PMID:12376530)
RGD PMID:12376530, PMID:21873635 MGI:2447499, RGD:13792537 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO
ISS
(PMID:9211901)
GO_REF:0000024
RGD
BHF-UCL
PMID:9211901 GO_REF:0000024 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 ISO
IEA
(PMID:15358760)
GO_REF:0000107
RGD
Ensembl
PMID:15358760 GO_REF:0000107 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    localization 6478
      maintenance of location 362
        lipid storage 86
          cholesterol storage 17
            cholesterol transport involved in cholesterol storage 1
            negative regulation of cholesterol storage 8
            positive regulation of cholesterol storage 7
            regulation of cholesterol storage + 15
Path 2
Term Annotations click to browse term
  biological_process 20020
    localization 6478
      macromolecule localization 3078
        lipid localization 523
          lipid storage 86
            cholesterol storage 17
              cholesterol transport involved in cholesterol storage 1
              negative regulation of cholesterol storage 8
              positive regulation of cholesterol storage 7
              regulation of cholesterol storage + 15
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.