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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cholesterol efflux
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Accession:GO:0010875 term browser browse the term
Definition:Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.



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positive regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (MGI:3047008|PMID:15210959) RGD PMID:15210959 MGI:3047008 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 involved_in
acts_upstream_of_or_within
ISO (PMID:23931754)
MGI:1352463|MGI:4461044 (MGI:5510615|PMID:23931754)
RGD PMID:23931754 MGI:5510615 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:25817392)
UniProt
RGD
PMID:25817392 GO_REF:0000024 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5553242|PMID:18429932)
Alzheimers_University_of_Toronto
RGD
PMID:18429932 GO_REF:0000024 MGI:5553242 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 involved_in ISO (PMID:23560799) RGD PMID:23560799 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3047008|PMID:15210959) RGD PMID:15210959 MGI:3047008 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in ISO (MGI:3047008|PMID:15210959) RGD PMID:15210959 MGI:3047008 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO
GO_REF:0000024
(PMID:18703020)
UniProt
RGD
PMID:18703020 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
ISS
IEA
(PMID:27472885)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:27472885 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P08226 (PMID:12042316), (PMID:12401887), (PMID:14754908)
(MGI:6448697|PMID:31902528)
Ensembl
RGD
PMID:12042316 PMID:12401887 PMID:14754908 PMID:31902528 GO_REF:0000107 MGI:6448697 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:24576892) RGD PMID:24576892 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16971496), (PMID:18599737), (PMID:18762277) RGD PMID:16971496 PMID:18599737 PMID:18762277 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 involved_in ISO (PMID:28082258)
(MGI:6162611|PMID:28082258)
RGD PMID:28082258 MGI:6162611 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340
JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:19481530) RGD PMID:19481530 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:4358638|PMID:19718435) RGD PMID:19718435 MGI:4358638 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Mir206 microRNA 206 acts_upstream_of ISO (PMID:24603323) RGD PMID:24603323 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16938301) RGD PMID:16938301 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in
acts_upstream_of_or_within
ISO (PMID:17186944)
MGI:2676312 (MGI:5510615|PMID:23931754)
(MGI:3720271|PMID:17657314), (MGI:3794353|PMID:16825483)
RGD PMID:16825483 PMID:17186944 PMID:17657314 PMID:23931754 MGI:3720271 MGI:3794353 MGI:5510615 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16141411), (PMID:17186944), (PMID:19481530)
(MGI:3794353|PMID:16825483)
Ensembl
UniProt
RGD
PMID:16141411 PMID:16825483 PMID:17186944 PMID:19481530 GO_REF:0000024 GO_REF:0000107 MGI:3794353 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Pltp phospholipid transfer protein involved_in ISO (PMID:24369175) RGD PMID:24369175 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Pon1 paraoxonase 1 involved_in ISO (PMID:15721011) RGD PMID:15721011 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of
involved_in
ISO (PMID:24751522)
(PMID:16530456)
RGD PMID:16530456 PMID:24751522 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptch1 patched 1 involved_in ISO (PMID:21931618) RGD PMID:21931618 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:3790014|PMID:17936707) RGD PMID:17936707 MGI:3790014 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6448697|PMID:31902528) RGD PMID:31902528 MGI:6448697 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Zdhhc8 zinc finger DHHC-type palmitoyltransferase 8 involved_in ISO (PMID:19556522) RGD PMID:19556522 NCBI chr11:82,755,110...82,769,280
Ensembl chr11:82,755,143...82,767,734
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    positive regulation of biological process 6711
      positive regulation of lipid localization 128
        positive regulation of lipid transport 100
          positive regulation of sterol transport 39
            positive regulation of cholesterol transport 39
              positive regulation of cholesterol efflux 26
Path 2
Term Annotations click to browse term
  biological_process 19746
    localization 5598
      establishment of localization 4939
        transport 4766
          organic substance transport 2913
            lipid transport 475
              sterol transport 145
                cholesterol transport 130
                  regulation of cholesterol transport 78
                    regulation of cholesterol efflux 51
                      positive regulation of cholesterol efflux 26
paths to the root