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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cholesterol efflux
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Accession:GO:0010875 term browser browse the term
Definition:Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.


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positive regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (PMID:25084135)
(MGI:3047008|PMID:15210959)
RGD PMID:15210959 PMID:25084135 MGI:3047008 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 acts_upstream_of_or_within
involved_in
ISO (PMID:23931754)
MGI:1352463|MGI:4461044 (MGI:5510615|PMID:23931754)
RGD PMID:23931754 MGI:5510615 NCBI chr 9:78,521,477...78,693,421
Ensembl chr 9:78,522,464...78,693,028
JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISO
ISS
(PMID:25817392)
GO_REF:0000024
RGD
UniProt
PMID:25817392 GO_REF:0000024 NCBI chr10:13,723,365...13,780,558
Ensembl chr10:13,723,405...13,779,963
JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5553242|PMID:18429932)
Alzheimers_University_of_Toronto
RGD
PMID:18429932 GO_REF:0000024 MGI:5553242 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 involved_in ISO
IEA
(PMID:23560799)
GO_REF:0000107
RGD
Ensembl
PMID:23560799 GO_REF:0000107 NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3047008|PMID:15210959) RGD PMID:15210959 MGI:3047008 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS
(PMID:18703020)
GO_REF:0000024
RGD
BHF-UCL
PMID:18703020 GO_REF:0000024 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISS
ISO
GO_REF:0000024
(PMID:27472885)
UniProt
RGD
PMID:27472885 GO_REF:0000024 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P08226 (PMID:12042316), (PMID:12401887), (PMID:14754908)
Ensembl
RGD
PMID:12042316 PMID:12401887 PMID:14754908 GO_REF:0000107 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:24576892)
GO_REF:0000107
RGD
Ensembl
PMID:24576892 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16971496), (PMID:18599737), (PMID:18762277) RGD PMID:16971496 PMID:18599737 PMID:18762277 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 involved_in ISO (PMID:28082258)
(MGI:6162611|PMID:28082258)
RGD PMID:28082258 MGI:6162611 NCBI chr 8:26,651,241...26,758,330
Ensembl chr 8:26,652,121...26,758,325
JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:19481530) RGD PMID:19481530 NCBI chr10:56,524,327...56,527,447
Ensembl chr10:56,524,468...56,526,987
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:4358638|PMID:19718435) RGD PMID:19718435 MGI:4358638 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16938301) RGD PMID:16938301 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in
acts_upstream_of_or_within
ISO (PMID:17186944)
(MGI:3720271|PMID:17657314), (MGI:3794353|PMID:16825483)
MGI:2676312 (MGI:5510615|PMID:23931754)
MGI:2676312 (MGI:3720271|PMID:17657314), (MGI:3794353|PMID:16825483), (MGI:5510615|PMID:23931754)
RGD PMID:16825483 PMID:17186944 PMID:17657314 PMID:23931754 MGI:3720271 MGI:3794353 MGI:5510615 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3794353|PMID:16825483)
(PMID:16141411), (PMID:17186944), (PMID:19481530)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:16141411 PMID:16825483 PMID:17186944 PMID:19481530 GO_REF:0000024 GO_REF:0000107 MGI:3794353 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Pltp phospholipid transfer protein involved_in ISO (PMID:24369175) RGD PMID:24369175 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Pon1 paraoxonase 1 involved_in ISO (PMID:15721011) RGD PMID:15721011 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ptch1 patched 1 involved_in ISO (PMID:21931618) RGD PMID:21931618 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:3790014|PMID:17936707) RGD PMID:17936707 MGI:3790014 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Zdhhc8 zinc finger DHHC-type palmitoyltransferase 8 involved_in ISO (PMID:19556522) RGD PMID:19556522 NCBI chr11:86,903,122...86,917,261
Ensembl chr11:86,903,122...86,915,715
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    positive regulation of biological process 6628
      positive regulation of lipid localization 132
        positive regulation of lipid transport 110
          positive regulation of sterol transport 36
            positive regulation of cholesterol transport 36
              positive regulation of cholesterol efflux 22
Path 2
Term Annotations click to browse term
  biological_process 20082
    localization 6506
      establishment of localization 4918
        transport 4755
          ion transport 3516
            anion transport 2698
              organic substance transport 2574
                lipid transport 481
                  sterol transport 117
                    regulation of sterol transport 64
                      positive regulation of sterol transport 36
                        positive regulation of cholesterol transport 36
                          positive regulation of cholesterol efflux 22
paths to the root