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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of cholesterol efflux
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Accession:GO:0010874 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.


show annotations for term's descendants           Sort by:
regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6508518|PMID:32687853)
(PMID:25125465)		 UniProt
RGD		 PMID:25125465 PMID:32687853 GO_REF:0000024 MGI:6508518 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976 		JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 involved_in ISO (PMID:28882873) RGD PMID:28882873 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20544018)		 UniProt
RGD		 PMID:20544018 GO_REF:0000024 NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179 		JBrowse link
G LOC100361543 RhoA activator C11orf59-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:34,637,461...34,638,516
Ensembl chr  X:34,637,459...34,638,516 		JBrowse link
G Naxe NAD(P)HX epimerase involved_in ISS
ISO		 GO_REF:0000024
ZFIN:ZDB-MRPHLNO-130813-3 (PMID:23719382)		 UniProt
RGD		 PMID:23719382 GO_REF:0000024 NCBI chr 2:173,518,966...173,521,048
Ensembl chr 2:173,518,971...173,521,040 		JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:5800596|PMID:27383786)
GO_REF:0000024		 RGD
UniProt		 PMID:27383786 PMID:21873635 GO_REF:0000024 MGI:5800596, RGD:13792537 NCBI chr 5:97,603,329...97,708,103
Ensembl chr 5:97,609,392...97,736,270 		JBrowse link
G Ttc39d tetratricopeptide repeat domain 39D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:14,802,753...14,811,516
Ensembl chr 6:14,786,089...14,811,978 		JBrowse link
negative regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:21810484)
GO_REF:0000107		 RGD
Ensembl		 PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:12042316) RGD PMID:12042316 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Egf epidermal growth factor involved_in ISO (MGI:4460848|PMID:20037141) RGD PMID:20037141 MGI:4460848 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (MGI:4411947|PMID:19752193) RGD PMID:19752193 MGI:4411947 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Mir128-1 microRNA 128-1 acts_upstream_of
involved_in		 ISO (PMID:23990020)
(PMID:26501192)		 RGD PMID:23990020 PMID:26501192 NCBI chr13:39,699,449...39,699,530
Ensembl chr13:39,699,449...39,699,530 		JBrowse link
G Mir128-2 microRNA 128-2 acts_upstream_of
involved_in		 ISO (PMID:23990020)
(PMID:26501192)		 RGD PMID:23990020 PMID:26501192 NCBI chr 8:112,085,467...112,085,550
Ensembl chr 8:112,085,467...112,085,550 		JBrowse link
G Mir130b microRNA 130b involved_in ISO (PMID:26501192) RGD PMID:26501192 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244 		JBrowse link
G Mir144 microRNA 144 involved_in ISO UniProtKB:O95477 (PMID:23519695), (PMID:24733347) RGD PMID:23519695 PMID:24733347 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir145 microRNA 145 involved_in ISO (PMID:24135019) RGD PMID:24135019 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir148a microRNA 148a involved_in ISO (PMID:26437365), (PMID:26501192) RGD PMID:26437365 PMID:26501192 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858 		JBrowse link
G Mir19b1 microRNA 19b-1 involved_in ISO (PMID:25084135), (PMID:25765596) RGD PMID:25084135 PMID:25765596 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300 		JBrowse link
G Mir19b2 microRNA 19b-2 involved_in ISO (PMID:25084135), (PMID:25765596) RGD PMID:25084135 PMID:25765596 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167 		JBrowse link
G Mir206 microRNA 206 acts_upstream_of ISO (PMID:24603323) RGD PMID:24603323 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:24608080) RGD PMID:24608080 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:24608080), (PMID:26520906) RGD PMID:24608080 PMID:26520906 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir301b microRNA 301b involved_in ISO (PMID:26501192) RGD PMID:26501192 NCBI chr11:83,879,816...83,879,893
Ensembl chr11:83,879,816...83,879,893 		JBrowse link
G Mir33 microRNA 33 involved_in
acts_upstream_of		 ISO (PMID:20466885), (PMID:20566875), (PMID:20855588)
(PMID:20466882)		 RGD PMID:20466882 PMID:20466885 PMID:20566875 PMID:20855588 NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923 		JBrowse link
G Mir9-3 microRNA 9-3 involved_in ISO (PMID:29584810) RGD PMID:29584810 NCBI chr 1:133,440,049...133,440,138 JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA
ISO		 GO_REF:0000107
(MGI:5051938|PMID:20844270)		 Ensembl
RGD		 PMID:20844270 GO_REF:0000107 MGI:5051938 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO		 GO_REF:0000107
(MGI:5306540|PMID:21931618)		 Ensembl
RGD		 PMID:21931618 GO_REF:0000107 MGI:5306540 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:15358760)		 Ensembl
RGD		 PMID:15358760 GO_REF:0000107 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
positive regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (MGI:3047008|PMID:15210959) RGD PMID:15210959 MGI:3047008 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 involved_in
acts_upstream_of_or_within		 ISO (PMID:23931754)
MGI:1352463|MGI:4461044 (MGI:5510615|PMID:23931754)		 RGD PMID:23931754 MGI:5510615 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25817392)		 UniProt
RGD		 PMID:25817392 GO_REF:0000024 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5553242|PMID:18429932)		 Alzheimers_University_of_Toronto
RGD		 PMID:18429932 GO_REF:0000024 MGI:5553242 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 involved_in ISO (PMID:23560799) RGD PMID:23560799 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3047008|PMID:15210959) RGD PMID:15210959 MGI:3047008 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in ISO (MGI:3047008|PMID:15210959) RGD PMID:15210959 MGI:3047008 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:18703020)		 UniProt
RGD		 PMID:18703020 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA
ISS		 (PMID:27472885)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:27472885 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(MGI:6448697|PMID:31902528)
UniProtKB:P08226 (PMID:12042316), (PMID:12401887), (PMID:14754908)		 Ensembl
RGD		 PMID:12042316 PMID:12401887 PMID:14754908 PMID:31902528 GO_REF:0000107 MGI:6448697 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:24576892) RGD PMID:24576892 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16971496), (PMID:18599737), (PMID:18762277) RGD PMID:16971496 PMID:18599737 PMID:18762277 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 involved_in ISO (PMID:28082258)
(MGI:6162611|PMID:28082258)		 RGD PMID:28082258 MGI:6162611 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:19481530) RGD PMID:19481530 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:4358638|PMID:19718435) RGD PMID:19718435 MGI:4358638 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Mir206 microRNA 206 acts_upstream_of ISO (PMID:24603323) RGD PMID:24603323 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16938301) RGD PMID:16938301 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:17186944)
(MGI:3720271|PMID:17657314), (MGI:3794353|PMID:16825483)
MGI:2676312 (MGI:5510615|PMID:23931754)		 RGD PMID:16825483 PMID:17186944 PMID:17657314 PMID:23931754 MGI:3720271 MGI:3794353 MGI:5510615 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3794353|PMID:16825483)
(PMID:16141411), (PMID:17186944), (PMID:19481530)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:16141411 PMID:16825483 PMID:17186944 PMID:19481530 GO_REF:0000024 GO_REF:0000107 MGI:3794353 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Pltp phospholipid transfer protein involved_in ISO (PMID:24369175) RGD PMID:24369175 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647 		JBrowse link
G Pon1 paraoxonase 1 involved_in ISO (PMID:15721011) RGD PMID:15721011 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of
involved_in		 ISO (PMID:24751522)
(PMID:16530456)		 RGD PMID:16530456 PMID:24751522 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptch1 patched 1 involved_in ISO (PMID:21931618) RGD PMID:21931618 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:3790014|PMID:17936707) RGD PMID:17936707 MGI:3790014 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6448697|PMID:31902528) RGD PMID:31902528 MGI:6448697 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Zdhhc8 zinc finger DHHC-type palmitoyltransferase 8 involved_in ISO (PMID:19556522) RGD PMID:19556522 NCBI chr11:82,755,110...82,769,280
Ensembl chr11:82,755,143...82,767,734 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    localization 5598
      regulation of localization 2442
        regulation of lipid localization 209
          regulation of lipid transport 172
            regulation of sterol transport 78
              regulation of cholesterol transport 78
                regulation of cholesterol efflux 51
                  negative regulation of cholesterol efflux 21
                  positive regulation of cholesterol efflux 26
Path 2
Term Annotations click to browse term
  biological_process 19748
    localization 5598
      establishment of localization 4938
        transport 4765
          organic substance transport 2913
            lipid transport 475
              sterol transport 145
                cholesterol transport 130
                  regulation of cholesterol transport 78
                    regulation of cholesterol efflux 51
                      negative regulation of cholesterol efflux 21
                      positive regulation of cholesterol efflux 26
paths to the root