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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cholesterol esterification
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Accession:GO:0010872 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


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regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISS
ISO
GO_REF:0000024
(PMID:15238223), (PMID:24201375)
UniProt
RGD
PMID:15238223 PMID:24201375 GO_REF:0000024 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) RGD PMID:16556852 MGI:3852307 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20544018)
UniProt
RGD
PMID:20544018 GO_REF:0000024 NCBI chr 1:166,991,474...166,997,045
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G LOC100361543 RhoA activator C11orf59-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:37,261,428...37,262,470
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IMP
IEA
(PMID:21810484)
PMID:24201375
GO_REF:0000107
RGD
Ensembl
PMID:21810484, PMID:24201375 GO_REF:0000107, RGD:14697729 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Apoa1 apolipoprotein A1 involved_in IBA
ISO
PMID:21873635
(PMID:4335615)
RGD PMID:4335615, PMID:21873635 RGD:13792537 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
IBA
(PMID:1935934)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:1935934, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:15654758)
(MGI:3850619|PMID:15654758)
GO_REF:0000107
RGD
Ensembl
PMID:15654758 GO_REF:0000107 MGI:3850619 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) RGD PMID:18403318 NCBI chr18:25,982,210...25,997,555
Ensembl chr18:25,984,638...25,997,555
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    cellular process 18451
      regulation of cellular process 12342
        regulation of cellular metabolic process 5966
          regulation of cholesterol esterification 12
            negative regulation of cholesterol esterification 1
            positive regulation of cholesterol esterification 8
Path 2
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      primary metabolic process 10619
        lipid metabolic process 1361
          cellular lipid metabolic process 1018
            lipid modification 220
              steroid esterification 16
                sterol esterification 16
                  cholesterol esterification 16
                    regulation of cholesterol esterification 12
                      negative regulation of cholesterol esterification 1
                      positive regulation of cholesterol esterification 8
paths to the root