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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cholesterol esterification
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Accession:GO:0010872 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


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regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA
IMP
(PMID:24201375)
(PMID:15238223)
ARUK-UCL
UniProt
PMID:15238223 PMID:24201375 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISS (PMID:16556852) BHF-UCL PMID:16556852 NCBI chr21:42,199,689...42,304,387
Ensembl chr21:42,199,689...42,297,244
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IMP (PMID:20544018) UniProt PMID:20544018 NCBI chr11:72,097,292...72,103,297
Ensembl chr11:72,085,895...72,103,297
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISS
IDA
(PMID:24201375)
(PMID:21810484)
ARUK-UCL PMID:21810484 PMID:24201375 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in IDA (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in IMP (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G APOA1 apolipoprotein A1 involved_in IBA
IDA
(PMID:21873635)
(PMID:4335615)
GO_Central
BHF-UCL
PMID:4335615 PMID:21873635 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOA2 apolipoprotein A2 involved_in IDA (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
JBrowse link
G APOA4 apolipoprotein A4 involved_in IDA
IBA
(PMID:1935934)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:1935934 PMID:21873635 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
JBrowse link
G APOA5 apolipoprotein A5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420
JBrowse link
G APOC1 apolipoprotein C1 involved_in TAS (PMID:18992221) BHF-UCL PMID:18992221 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349
JBrowse link
G APOE apolipoprotein E involved_in IDA (PMID:15654758) BHF-UCL PMID:15654758 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IDA (PMID:18403318) BHF-UCL PMID:18403318 NCBI chr 5:111,491,422...111,512,567
Ensembl chr 5:111,496,033...111,512,590
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18666
    cellular process 17730
      regulation of cellular process 12091
        regulation of cellular metabolic process 6507
          regulation of cholesterol esterification 12
            negative regulation of cholesterol esterification 1
            positive regulation of cholesterol esterification 9
Path 2
Term Annotations click to browse term
  biological_process 18666
    metabolic process 12186
      primary metabolic process 10915
        lipid metabolic process 1516
          cellular lipid metabolic process 1135
            lipid modification 229
              steroid esterification 16
                sterol esterification 16
                  cholesterol esterification 16
                    regulation of cholesterol esterification 12
                      negative regulation of cholesterol esterification 1
                      positive regulation of cholesterol esterification 9
paths to the root