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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cholesterol esterification
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Accession:GO:0010872 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


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regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:15238223)
(PMID:24201375)
UniProt
ARUK-UCL
PMID:15238223 PMID:24201375 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) BHF-UCL PMID:16556852 MGI:3852307 NCBI chrNW_004955407:39,410,262...39,459,383
Ensembl chrNW_004955407:39,410,262...39,459,383
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISO (PMID:20544018) UniProt PMID:20544018 NCBI chrNW_004955414:19,228,615...19,235,523
Ensembl chrNW_004955414:19,228,615...19,247,765
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484)
PMID:24201375
ARUK-UCL PMID:21810484 PMID:24201375 RGD:14697729 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200
JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
JBrowse link
G Agtr1 angiotensin II receptor type 1 involved_in ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:4335615) BHF-UCL PMID:4335615 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO (PMID:1935934) BHF-UCL PMID:1935934 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:15654758)
(MGI:3850619|PMID:15654758)
BHF-UCL PMID:15654758 MGI:3850619 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Stard4 StAR related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chrNW_004955418:3,637,390...3,652,054
Ensembl chrNW_004955418:3,638,399...3,648,402
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11938
    cellular process 11169
      regulation of cellular process 7863
        regulation of cellular metabolic process 4342
          regulation of cholesterol esterification 10
            negative regulation of cholesterol esterification 1
            positive regulation of cholesterol esterification 7
Path 2
Term Annotations click to browse term
  biological_process 11938
    metabolic process 7522
      primary metabolic process 6659
        lipid metabolic process 934
          cellular lipid metabolic process 698
            lipid modification 148
              steroid esterification 13
                sterol esterification 13
                  cholesterol esterification 13
                    regulation of cholesterol esterification 10
                      negative regulation of cholesterol esterification 1
                      positive regulation of cholesterol esterification 7
paths to the root