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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cholesterol esterification
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Accession:GO:0010872 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


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regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:24201375)
(PMID:15238223)
ARUK-UCL
UniProt
PMID:15238223 PMID:24201375 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) BHF-UCL PMID:16556852 MGI:3852307 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISO (PMID:20544018) UniProt PMID:20544018 NCBI chr11:67,177,580...67,183,631
Ensembl chr11:70,390,141...70,407,246
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484)
PMID:24201375
ARUK-UCL PMID:21810484 PMID:24201375 RGD:14697729 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380
JBrowse link
G APOA1 apolipoprotein A1 involved_in ISO (PMID:4335615) BHF-UCL PMID:4335615 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122
JBrowse link
G APOA2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959
JBrowse link
G APOA4 apolipoprotein A4 involved_in ISO (PMID:1935934) BHF-UCL PMID:1935934 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382
JBrowse link
G APOE apolipoprotein E involved_in ISO (PMID:15654758)
(MGI:3850619|PMID:15654758)
BHF-UCL PMID:15654758 MGI:3850619 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chr 5:106,855,990...106,873,384
Ensembl chr 5:112,657,516...112,675,165
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12612
    cellular process 11742
      regulation of cellular process 8216
        regulation of cellular metabolic process 4525
          regulation of cholesterol esterification 10
            negative regulation of cholesterol esterification 1
            positive regulation of cholesterol esterification 7
Path 2
Term Annotations click to browse term
  biological_process 12612
    metabolic process 7890
      primary metabolic process 6954
        lipid metabolic process 1004
          cellular lipid metabolic process 749
            lipid modification 161
              steroid esterification 13
                sterol esterification 13
                  cholesterol esterification 13
                    regulation of cholesterol esterification 10
                      negative regulation of cholesterol esterification 1
                      positive regulation of cholesterol esterification 7
paths to the root