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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of cholesterol esterification
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Accession:GO:0010872 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


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regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:24201375)
(PMID:15238223)		 ARUK-UCL
Ensembl
UniProt		 PMID:15238223 PMID:24201375 GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,177,580...67,183,631
Ensembl chr11:70,390,141...70,407,246 		JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G APOA1 apolipoprotein A1 involved_in ISO (PMID:4335615) BHF-UCL PMID:4335615 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G APOA2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOA4 apolipoprotein A4 involved_in ISO (PMID:1935934) BHF-UCL PMID:1935934 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382 		JBrowse link
G APOE apolipoprotein E involved_in ISO (PMID:15654758) BHF-UCL PMID:15654758 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chr 5:106,855,990...106,873,384
Ensembl chr 5:112,657,516...112,675,165 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15332
    cellular process 14174
      regulation of cellular process 9645
        regulation of cellular metabolic process 4918
          regulation of cholesterol esterification 9
            negative regulation of cholesterol esterification 1
            positive regulation of cholesterol esterification 7
Path 2
Term Annotations click to browse term
  biological_process 15332
    metabolic process 10018
      primary metabolic process 8891
        lipid metabolic process 1208
          cellular lipid metabolic process 875
            lipid modification 187
              steroid esterification 12
                sterol esterification 12
                  cholesterol esterification 12
                    regulation of cholesterol esterification 9
                      negative regulation of cholesterol esterification 1
                      positive regulation of cholesterol esterification 7
paths to the root