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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cholesterol esterification
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Accession:GO:0010872 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.



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regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISS
ISO
GO_REF:0000024
(PMID:15238223), (PMID:24201375)
UniProt
RGD
PMID:15238223 PMID:24201375 GO_REF:0000024 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) RGD PMID:16556852 MGI:3852307 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20544018)
UniProt
RGD
PMID:20544018 GO_REF:0000024 NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179
JBrowse link
G LOC100361543 RhoA activator C11orf59-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:34,637,461...34,638,516
Ensembl chr  X:34,637,459...34,638,516
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IMP
IEA
(PMID:21810484)
PMID:24201375
GO_REF:0000107
RGD
Ensembl
PMID:21810484 PMID:24201375 GO_REF:0000107, RGD:14697729 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07070085.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Agt angiotensinogen involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Apoa1 apolipoprotein A1 involved_in IBA
ISO
PMID:21873635
(PMID:4335615)
RGD PMID:4335615 PMID:21873635 RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
IBA
(PMID:1935934)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:1935934 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:15654758)
(MGI:3850619|PMID:15654758)
GO_REF:0000107
RGD
Ensembl
PMID:15654758 GO_REF:0000107 MGI:3850619 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) RGD PMID:18403318 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    cellular process 18319
      regulation of cellular process 12364
        regulation of cellular metabolic process 5984
          regulation of cholesterol esterification 13
            negative regulation of cholesterol esterification 1
            positive regulation of cholesterol esterification 9
Path 2
Term Annotations click to browse term
  biological_process 19512
    metabolic process 11791
      primary metabolic process 10525
        lipid metabolic process 1408
          cellular lipid metabolic process 1038
            lipid modification 228
              steroid esterification 17
                sterol esterification 17
                  cholesterol esterification 17
                    regulation of cholesterol esterification 13
                      negative regulation of cholesterol esterification 1
                      positive regulation of cholesterol esterification 9
paths to the root