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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of myotube differentiation
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Accession:GO:0010832 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


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negative regulation of myotube differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (PMID:18302940)
(PMID:23824195)		 MGI PMID:18302940 PMID:23824195 NCBI chr28:10,838,677...10,848,406
Ensembl chr28:10,834,411...10,848,406 		JBrowse link
G BDNF brain derived neurotrophic factor involved_in ISO PMID:16723531 BHF-UCL PMID:16723531 RGD:1580249 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480 		JBrowse link
G BHLHA15 basic helix-loop-helix family member a15 involved_in ISO (MGI:5607242|PMID:17612490) UniProt PMID:17612490 MGI:5607242 NCBI chr 6:11,112,233...11,115,776
Ensembl chr 6:11,114,694...11,115,257 		JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:21,464,302...21,469,119 JBrowse link
G CCN3 cellular communication network factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:18,507,586...18,515,755
Ensembl chr13:18,507,580...18,514,619 		JBrowse link
G CEACAM28 carcinoembryonic antigen-related cell adhesion molecule 28 involved_in ISO (PMID:10931872), (PMID:8408226) UniProt PMID:8408226 PMID:10931872 NCBI chr 1:111,812,571...111,834,985
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:7737360 RGD:151665771 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:19308989 RGD:9587764 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340 		JBrowse link
G HDAC1 histone deacetylase 1 NOT|involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 2:68,901,339...68,936,473
Ensembl chr 2:68,901,651...68,936,186 		JBrowse link
G HDAC3 histone deacetylase 3 NOT|involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 2:36,583,283...36,598,121
Ensembl chr 2:36,583,283...36,597,682 		JBrowse link
G HDAC4 histone deacetylase 4 involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478 		JBrowse link
G HDAC5 histone deacetylase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,261,075...19,297,669
Ensembl chr 9:19,260,893...19,297,623 		JBrowse link
G MYOCD myocardin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17940050) Ensembl
MGI		 PMID:17940050 GO_REF:0000107 NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327 		JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:39,240,755...39,254,585
Ensembl chr 4:39,244,286...39,247,592 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G PLPP7 phospholipid phosphatase 7 (inactive) involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19704009) Ensembl
MGI		 PMID:19704009 GO_REF:0000107 NCBI chr 9:52,781,110...52,796,763
Ensembl chr 9:52,781,020...52,796,433 		JBrowse link
G RPL3L ribosomal protein L3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,971,098...38,981,466
Ensembl chr 6:38,974,018...38,982,012 		JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,275,719...18,282,905
Ensembl chr26:18,260,923...18,282,409 		JBrowse link
G TRIM72 tripartite motif containing 72 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23965929) Ensembl
MGI		 PMID:23965929 GO_REF:0000107 NCBI chr 6:17,031,175...17,053,399
Ensembl chr 6:17,031,913...17,039,556 		JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:5607242|PMID:17612490) UniProt PMID:17612490 MGI:5607242 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      negative regulation of cellular process 5355
        negative regulation of cell differentiation 773
          negative regulation of muscle cell differentiation 81
            negative regulation of striated muscle cell differentiation 46
              negative regulation of myotube differentiation 20
                negative regulation of skeletal muscle fiber differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cellular developmental process 4609
        cell differentiation 4608
          muscle cell differentiation 495
            striated muscle cell differentiation 367
              myotube differentiation 150
                regulation of myotube differentiation 50
                  negative regulation of myotube differentiation 20
                    negative regulation of skeletal muscle fiber differentiation + 0
paths to the root