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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of myotube differentiation
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Accession:GO:0010832 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


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negative regulation of myotube differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (PMID:18302940), (PMID:23824195) RGD PMID:18302940 PMID:23824195 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566 		JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in IMP PMID:16723531 BHF-UCL PMID:16723531 RGD:1580249 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5607242|PMID:17612490)		 UniProt
RGD		 PMID:17612490 GO_REF:0000024 MGI:5607242 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 involved_in ISO
IEA		 (MGI:5297791|PMID:12657651)
GO_REF:0000107		 RGD
Ensembl		 PMID:12657651 GO_REF:0000107 MGI:5297791 NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12050162)		 UniProt
RGD		 PMID:12050162 GO_REF:0000024 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:7737360 RGD:151665771 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Daxx death-domain associated protein IDA RGD PMID:19308989 RGD:9587764 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Hdac1 histone deacetylase 1 NOT|involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac3 histone deacetylase 3 NOT|involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hdac5 histone deacetylase 5 involved_in ISO (PMID:10983972), (PMID:11081517) RGD PMID:10983972 PMID:11081517 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Myocd myocardin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3849559 (PMID:17940050)		 Ensembl
RGD		 PMID:17940050 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in ISO
IEA		 (PMID:15653675)
GO_REF:0000107		 RGD
Ensembl		 PMID:15653675 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:5319604|PMID:18299578) RGD PMID:18299578 MGI:5319604 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Plpp7 phospholipid phosphatase 7 (inactive) acts_upstream_of_or_within ISO MGI:1928394 (PMID:19704009) RGD PMID:19704009 NCBI chr 3:15,384,461...15,398,820
Ensembl chr 3:15,384,492...15,398,883 		JBrowse link
G Rpl3l ribosomal protein L3-like involved_in ISO (MGI:6838892|PMID:26684695) RGD PMID:26684695 MGI:6838892 NCBI chr10:13,753,914...13,764,458
Ensembl chr10:13,753,886...13,764,457 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (MGI:6294241|PMID:22579779) RGD PMID:22579779 MGI:6294241 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689 		JBrowse link
G Trim72 tripartite motif containing 72 acts_upstream_of_or_within ISO (PMID:23965929) RGD PMID:23965929 NCBI chr 1:182,613,753...182,621,613
Ensembl chr 1:182,613,712...182,621,606 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (MGI:5607242|PMID:17612490) RGD PMID:17612490 MGI:5607242 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    cellular process 18524
      negative regulation of cellular process 5358
        negative regulation of cell differentiation 798
          negative regulation of muscle cell differentiation 78
            negative regulation of striated muscle cell differentiation 46
              negative regulation of myotube differentiation 19
                negative regulation of skeletal muscle fiber differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 20115
    cellular process 18524
      cellular developmental process 4728
        cell differentiation 4727
          muscle cell differentiation 484
            striated muscle cell differentiation 363
              myotube differentiation 146
                regulation of myotube differentiation 48
                  negative regulation of myotube differentiation 19
                    negative regulation of skeletal muscle fiber differentiation + 0
paths to the root