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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of centrosome duplication
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Accession:GO:0010826 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.


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negative regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnf cyclin F involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4819440|PMID:20596027)
(PMID:20596027)
UniProt
RGD
PMID:20596027 GO_REF:0000024 MGI:4819440 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Cenatac centrosomal AT-AC splicing factor involved_in ISO (PMID:31722219) RGD PMID:31722219 NCBI chr 8:48,729,695...48,736,574
Ensembl chr 8:48,729,835...48,736,506
JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO (PMID:16041368) RGD PMID:16041368 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Nubp1 nucleotide binding protein 1 acts_upstream_of_or_within ISO (MGI:3625381|PMID:16638812), (MGI:5463135|PMID:23028652) RGD PMID:16638812 PMID:23028652 MGI:3625381 MGI:5463135 NCBI chr10:5,333,378...5,343,949
Ensembl chr10:5,333,378...5,344,121
JBrowse link
G Tmem67 transmembrane protein 67 involved_in IMP
ISO
IEA
(MGI:4353840|PMID:19515853)
GO_REF:0000107
(PMID:19515853)
RGD
Ensembl
PMID:19515853, PMID:19515853 GO_REF:0000107 MGI:4353840, RGD:8554306 NCBI chr 5:25,666,138...25,721,056
Ensembl chr 5:25,666,137...25,721,072
JBrowse link
negative regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4830038|PMID:20627074)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20627074 GO_REF:0000024 GO_REF:0000107 MGI:4830038 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Mdm1 Mdm1 nuclear protein involved_in IEA
ISS
ISO
GO_REF:0000002
GO_REF:0000024
(PMID:26337392)
InterPro
UniProt
RGD
PMID:26337392 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:61,165,652...61,200,865
Ensembl chr 7:61,165,640...61,200,879
JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:25385835) RGD PMID:25385835 NCBI chr 1:220,048,740...220,067,124
Ensembl chr 1:220,048,873...220,067,124
JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA
(PMID:23769972)
PMID:21873635
RGD PMID:23769972, PMID:21873635 RGD:13792537 NCBI chr10:74,436,165...74,568,636
Ensembl chr10:74,436,208...74,568,493
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      cell cycle process 1174
        centrosome duplication 80
          negative regulation of centrosome duplication 11
            negative regulation of centriole replication 6
Path 2
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      cellular component organization or biogenesis 6721
        cellular component organization 6481
          organelle organization 4060
            cytoskeleton organization 1453
              microtubule cytoskeleton organization 639
                microtubule organizing center organization 150
                  centrosome cycle 137
                    regulation of centrosome cycle 57
                      regulation of centrosome duplication 51
                        negative regulation of centrosome duplication 11
                          negative regulation of centriole replication 6
paths to the root