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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of centrosome duplication
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Accession:GO:0010824 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.


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regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07007744.2 RGD:13792537
G AABR07041089.1 RGD:13792537
G AABR07055527.1 RGD:13792537
G AABR07067023.1 RGD:1600115
G AABR07067024.1 RGD:1600115
G Cep131 centrosomal protein 131 JBrowse link 10 109,243,240 109,267,636 RGD:1624291
RGD:13792537
G Chmp1a charged multivesicular body protein 1A JBrowse link 19 56,001,724 56,010,004 RGD:1624291
RGD:1600115
G Chmp1b charged multivesicular body protein 1B JBrowse link 18 62,923,620 62,926,150 RGD:1624291
G Chmp2a charged multivesicular body protein 2A JBrowse link 1 65,540,808 65,543,708 RGD:1624291
G Chmp2b charged multivesicular body protein 2B JBrowse link 11 2,666,405 2,692,213 RGD:1624291
RGD:1600115
G Chmp3 charged multivesicular body protein 3 JBrowse link 4 99,449,213 99,496,156 RGD:1624291
G Chmp4b charged multivesicular body protein 4B JBrowse link 3 150,188,275 150,227,453 RGD:1624291
G Chmp4c charged multivesicular body protein 4C JBrowse link 2 93,574,554 93,641,497 RGD:1600115
RGD:1624291
G Chmp5 charged multivesicular body protein 5 JBrowse link 5 57,267,312 57,284,455 RGD:1624291
RGD:1600115
G Chordc1 cysteine and histidine rich domain containing 1 JBrowse link 8 17,421,552 17,445,513 RGD:1624291
RGD:1600115
G Fbxw5 F-box and WD repeat domain containing 5 JBrowse link 3 2,726,705 2,731,213 RGD:1624291
RGD:1600115
G Gen1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 6 36,910,064 36,940,868 RGD:1624291
RGD:1600115
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
RGD:13792537
G Pdcd6ip programmed cell death 6 interacting protein JBrowse link 8 121,916,233 121,973,145 RGD:1624291
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 9 26,164,969 26,736,704 RGD:1624291
G Vps4b vacuolar protein sorting 4 homolog B JBrowse link 13 26,825,261 26,850,460 RGD:1624291
G Xpo1 exportin 1 JBrowse link 14 108,007,421 108,049,088 RGD:1624291
RGD:1600115
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
RGD:1600115
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chmp2a charged multivesicular body protein 2A JBrowse link 1 65,540,808 65,543,708 RGD:1624291
RGD:1600115
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Kat2a lysine acetyltransferase 2A JBrowse link 10 88,611,586 88,619,558 RGD:1600115
RGD:1624291
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:1624291
G Mdm1 Mdm1 nuclear protein JBrowse link 7 61,165,652 61,200,865 RGD:1600115
RGD:1624291
G Rbm14 RNA binding motif protein 14 JBrowse link 1 220,048,740 220,067,124 RGD:1624291
RGD:1600115
G Trim37 tripartite motif-containing 37 JBrowse link 10 74,436,165 74,568,636 RGD:1624291
RGD:1600115
negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnf cyclin F JBrowse link 10 13,594,687 13,619,935 RGD:1624291
RGD:1600115
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
G Nubp1 nucleotide binding protein 1 JBrowse link 10 5,333,378 5,343,949 RGD:1624291
RGD:1600115
G Tmem67 transmembrane protein 67 JBrowse link 5 25,666,138 25,721,056 RGD:8554306
RGD:1624291
RGD:1600115
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1600115
RGD:1624291
G Cep120 centrosomal protein 120 JBrowse link 18 48,658,495 48,720,570 RGD:1600115
RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:1600115
RGD:1624291
G Vps4b vacuolar protein sorting 4 homolog B JBrowse link 13 26,825,261 26,850,460 RGD:1624291
RGD:1600115
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
RGD:1600115
G Plk4 polo-like kinase 4 JBrowse link 2 127,686,911 127,705,518 RGD:1600115
RGD:1624291
positive regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Azin1 antizyme inhibitor 1 JBrowse link 7 77,345,646 77,372,398 RGD:14700805
G Cep120 centrosomal protein 120 JBrowse link 18 48,658,495 48,720,570 RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:1600115
RGD:1624291
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
G Poc1a POC1 centriolar protein A JBrowse link 8 114,982,764 115,050,844 RGD:1624291
RGD:1600115
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1624291
RGD:1600115
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alms1 ALMS1, centrosome and basal body associated protein JBrowse link 4 117,371,544 117,472,310 RGD:13792537
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:13792537
G Cep295nl CEP295 N-terminal like JBrowse link 10 107,363,511 107,381,280 RGD:13792537
G Cep76 centrosomal protein 76 JBrowse link 18 63,364,990 63,394,766 RGD:1624291
RGD:1600115
G LOC100302465 hypothetical LOC100302465 JBrowse link 1 206,324,763 206,417,143 RGD:13792537
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
RGD:1600115
G Plk2 polo-like kinase 2 JBrowse link 2 41,911,143 41,916,901 RGD:1600115
RGD:1624291
G Spice1 spindle and centriole associated protein 1 JBrowse link 11 61,250,649 61,294,116 RGD:1624291
RGD:13792537
RGD:1600115
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    cellular process 17125
      cell cycle process 1171
        centrosome duplication 72
          regulation of centrosome duplication 47
            negative regulation of centrosome duplication + 11
            positive regulation of centrosome duplication + 10
            regulation of centriole replication + 21
Path 2
Term Annotations click to browse term
  biological_process 19245
    cellular component organization or biogenesis 6449
      cellular component organization 6239
        organelle organization 3773
          cytoskeleton organization 1384
            microtubule cytoskeleton organization 598
              microtubule organizing center organization 141
                centrosome cycle 130
                  centrosome duplication 72
                    regulation of centrosome duplication 47
                      negative regulation of centrosome duplication + 11
                      positive regulation of centrosome duplication + 10
                      regulation of centriole replication + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.