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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of centrosome duplication
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Accession:GO:0010824 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.



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regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07007744.2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:27,601,232...27,601,825 JBrowse link
G AABR07025089.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:26,091,905...26,186,434 JBrowse link
G AABR07041089.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:111,554,752...111,557,411 JBrowse link
G AABR07055527.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:4,352,572...4,353,409 JBrowse link
G AABR07067023.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:22,549,513...23,037,381 JBrowse link
G AABR07067024.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002
G Cep131 centrosomal protein 131 involved_in IBA
ISO
PMID:21873635
(PMID:22797915)
RGD PMID:22797915 PMID:21873635 RGD:13792537 NCBI chr10:105,346,015...105,370,380
Ensembl chr10:105,346,015...105,370,380
JBrowse link
G Chmp1a charged multivesicular body protein 1A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr19:51,238,153...51,246,433
Ensembl chr19:51,238,160...51,246,436
JBrowse link
G Chmp1b charged multivesicular body protein 1B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr18:60,740,349...60,742,879 JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:73,660,045...73,662,894
Ensembl chr 1:73,660,046...73,662,452
JBrowse link
G Chmp2b charged multivesicular body protein 2B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr11:3,338,007...3,364,357
Ensembl chr11:3,337,494...3,385,181
JBrowse link
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959
JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 3:143,170,822...143,211,376
Ensembl chr 3:143,170,902...143,210,844
JBrowse link
G Chmp4c charged multivesicular body protein 4C involved_in ISO
IEA
(PMID:20616062)
GO_REF:0000107
RGD
Ensembl
PMID:20616062 GO_REF:0000107 NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668
JBrowse link
G Chmp5 charged multivesicular body protein 5 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4441223|PMID:20230755)
UniProt
RGD
PMID:20230755 GO_REF:0000024 MGI:4441223 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Fbxw5 F-box and WD repeat domain containing 5 involved_in ISO
ISS
(PMID:21725316)
GO_REF:0000024
RGD
UniProt
PMID:21725316 GO_REF:0000024 NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23108668), (PMID:23166748) RGD PMID:23108668 PMID:23166748 NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401
JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:31722219) RGD PMID:31722219 NCBI chr 3:90,111,643...90,151,644
Ensembl chr 3:90,111,645...90,149,927
JBrowse link
G Npm1 nucleophosmin 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3604807 (MGI:3604166|PMID:16007073)
RGD PMID:16007073 PMID:21873635 MGI:3604166, RGD:13792537 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773
JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin involved_in ISO (PMID:20554582) RGD PMID:20554582 NCBI chr 9:22,547,396...23,037,443 JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:31722219)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:31722219 GO_REF:0000024 GO_REF:0000107 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229
JBrowse link
G Xpo1 exportin 1 acts_upstream_of_or_within ISO (MGI:3610707|PMID:16297385) RGD PMID:16297385 MGI:3610707 NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
negative regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4830038|PMID:20627074)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20627074 GO_REF:0000024 GO_REF:0000107 MGI:4830038 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782
JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166
JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr 9:6,562,525...6,667,064 JBrowse link
G Mdm1 Mdm1 nuclear protein involved_in IEA
ISO
ISS
GO_REF:0000002
(PMID:26337392)
GO_REF:0000024
InterPro
RGD
UniProt
PMID:26337392 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:53,729,603...53,766,034
Ensembl chr 7:53,729,610...53,766,034
JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:25385835) RGD PMID:25385835 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665
JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA
(PMID:23769972)
PMID:21873635
RGD PMID:23769972 PMID:21873635 RGD:13792537 NCBI chr10:71,943,384...72,075,567
Ensembl chr10:71,943,375...72,075,558
JBrowse link
negative regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnf cyclin F involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4819440|PMID:20596027)
(PMID:20596027)
UniProt
RGD
PMID:20596027 GO_REF:0000024 MGI:4819440 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
JBrowse link
G Cenatac centrosomal AT-AC splicing factor involved_in ISO (PMID:31722219) RGD PMID:31722219 NCBI chr 8:44,735,968...44,742,859
Ensembl chr 8:44,735,972...44,742,837
JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO (PMID:16041368) RGD PMID:16041368 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nubp1 nucleotide binding protein 1 acts_upstream_of_or_within ISO (MGI:3625381|PMID:16638812), (MGI:5463135|PMID:23028652) RGD PMID:16638812 PMID:23028652 MGI:3625381 MGI:5463135 NCBI chr10:5,260,237...5,270,835 JBrowse link
G Tmem67 transmembrane protein 67 involved_in IMP
ISO
IEA
(MGI:4353840|PMID:19515853)
GO_REF:0000107
(PMID:19515853)
RGD
Ensembl
PMID:19515853 PMID:19515853 GO_REF:0000107 MGI:4353840, RGD:8554306 NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
JBrowse link
positive regulation of centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J involved_in ISO (PMID:27185865) RGD PMID:27185865 NCBI chr15:30,626,946...30,690,384
Ensembl chr15:30,627,224...30,686,791
JBrowse link
G Cep120 centrosomal protein 120 involved_in ISO
IBA
(PMID:27185865)
PMID:21873635
RGD PMID:27185865 PMID:21873635 RGD:13792537 NCBI chr18:47,127,979...47,189,964
Ensembl chr18:47,127,981...47,189,964
JBrowse link
G Cep295 centrosomal protein 295 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:27185865)
Ensembl
UniProt
RGD
PMID:27185865 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229
JBrowse link
positive regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nup62 nucleoporin 62 involved_in ISO (PMID:24107630) RGD PMID:24107630 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174
JBrowse link
G Plk4 polo-like kinase 4 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:22349705)
(PMID:16244668), (PMID:17681131), (PMID:27796307)
UniProt
RGD
PMID:16244668 PMID:17681131 PMID:22349705 PMID:27796307 GO_REF:0000024 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
positive regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IMP RGD PMID:17667942 RGD:14700805 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Cep120 centrosomal protein 120 involved_in ISO (MGI:5635753|PMID:25251415) RGD PMID:25251415 MGI:5635753 NCBI chr18:47,127,979...47,189,964
Ensembl chr18:47,127,981...47,189,964
JBrowse link
G Cep295 centrosomal protein 295 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:25131205)
Ensembl
UniProt
RGD
PMID:25131205 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552
JBrowse link
G Npm1 nucleophosmin 1 acts_upstream_of_or_within ISO UniProtKB:Q28201 (MGI:3697024|PMID:17015463) RGD PMID:17015463 MGI:3697024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Poc1a POC1 centriolar protein A acts_upstream_of_or_within ISO MGI:2135614 (MGI:5700251|PMID:26496357) RGD PMID:26496357 MGI:5700251 NCBI chr 8:106,922,058...106,991,678
Ensembl chr 8:106,922,978...106,991,089
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000002
(MGI:3697024|PMID:17015463)
InterPro
RGD
PMID:17015463 GO_REF:0000002 MGI:3697024 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
JBrowse link
G Cenpj centromere protein J involved_in ISO (PMID:20531387) RGD PMID:20531387 NCBI chr15:30,626,946...30,690,384
Ensembl chr15:30,627,224...30,686,791
JBrowse link
G Cep295 centrosomal protein 295 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552
JBrowse link
G Cep295nl CEP295 N-terminal like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:103,562,190...103,581,183
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Cep76 centrosomal protein 76 involved_in ISO (PMID:19460342) RGD PMID:19460342 NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504
JBrowse link
G LOC100302465 hypothetical LOC100302465 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:189,059,744...189,293,353
Ensembl chr 1:189,059,746...189,293,435
JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO
ISS
(PMID:20352051)
GO_REF:0000024
RGD
UniProt
PMID:20352051 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Plk2 polo-like kinase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:15242618), (PMID:19001868), (PMID:20352051), (PMID:20531387)
UniProt
RGD
PMID:15242618 PMID:19001868 PMID:20352051 PMID:20531387 GO_REF:0000024 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Spice1 spindle and centriole associated protein 1 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:20736305)
UniProt
RGD
PMID:20736305 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:56,289,291...56,332,382
Ensembl chr11:56,290,540...56,332,447
JBrowse link
G Stil STIL, centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    cellular process 18252
      cell cycle process 1175
        centrosome duplication 80
          regulation of centrosome duplication 51
            negative regulation of centrosome duplication + 11
            positive regulation of centrosome duplication 6
            regulation of centriole replication + 20
Path 2
Term Annotations click to browse term
  biological_process 19391
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component organization 6250
          organelle organization 3788
            cytoskeleton organization 1452
              microtubule cytoskeleton organization 639
                microtubule organizing center organization 150
                  centrosome cycle 137
                    regulation of centrosome cycle 57
                      regulation of centrosome duplication 51
                        negative regulation of centrosome duplication + 11
                        positive regulation of centrosome duplication 6
                        regulation of centriole replication + 20
paths to the root