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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epithelial to mesenchymal transition
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Accession:GO:0010719 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


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negative regulation of epithelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipor1 adiponectin receptor 1 JBrowse link 13 51,240,470 51,260,233 RGD:1624291
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1600115
RGD:1624291
G Dact3 dishevelled-binding antagonist of beta-catenin 3 JBrowse link 1 78,800,754 78,812,483 RGD:1624291
G Efna1 ephrin A1 JBrowse link 2 188,588,808 188,596,156 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
RGD:1600115
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
G Hpn hepsin JBrowse link 1 89,534,112 89,549,575 RGD:1600115
RGD:13792537
RGD:1624291
G Il17rd interleukin 17 receptor D JBrowse link 16 2,670,471 2,737,271 RGD:1624291
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 JBrowse link 18 63,717,423 64,045,224 RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1600115
RGD:1624291
G Ovol2 ovo-like zinc finger 2 JBrowse link 3 138,433,990 138,464,511 RGD:1624291
G Pbld1 phenazine biosynthesis-like protein domain containing 1 JBrowse link 20 27,103,300 27,118,650 RGD:1624291
G Ppp2ca protein phosphatase 2 catalytic subunit alpha JBrowse link 10 37,534,449 37,554,861 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 JBrowse link 1 226,543,671 226,572,414 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
G Spred1 sprouty-related, EVH1 domain containing 1 JBrowse link 3 108,795,337 108,861,650 RGD:1624291
G Spred2 sprouty-related, EVH1 domain containing 2 JBrowse link 14 104,268,362 104,290,206 RGD:1600115
RGD:1624291
G Spred3 sprouty-related, EVH1 domain containing 3 JBrowse link 1 88,101,213 88,112,719 RGD:1624291
G Spry1 sprouty RTK signaling antagonist 1 JBrowse link 2 124,400,689 124,405,331 RGD:1624291
G Spry2 sprouty RTK signaling antagonist 2 JBrowse link 15 90,172,769 90,177,823 RGD:1624291
G Strap serine/threonine kinase receptor associated protein JBrowse link 4 171,730,629 171,744,877 RGD:1624291
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:1624291
G Trim62 tripartite motif-containing 62 JBrowse link 5 147,068,725 147,099,024 RGD:1624291
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:11568680
G Usf3 upstream transcription factor family member 3 JBrowse link 11 61,427,140 61,499,668 RGD:1624291
RGD:13792537
G Vasn vasorin JBrowse link 10 11,121,041 11,131,548 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
negative regulation of neural crest formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fuz fuzzy planar cell polarity protein JBrowse link 1 100,891,832 100,896,811 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    multicellular organismal process 8944
      negative regulation of multicellular organismal process 1381
        negative regulation of epithelial to mesenchymal transition 34
          negative regulation of cardiac epithelial to mesenchymal transition + 2
          negative regulation of neural crest formation + 1
Path 2
Term Annotations click to browse term
  biological_process 19678
    developmental process 6729
      anatomical structure development 6177
        multicellular organism development 5635
          system development 5211
            animal organ development 3972
              mesenchyme development 289
                mesenchymal cell differentiation 229
                  epithelial to mesenchymal transition 150
                    regulation of epithelial to mesenchymal transition 95
                      negative regulation of epithelial to mesenchymal transition 34
                        negative regulation of cardiac epithelial to mesenchymal transition + 2
                        negative regulation of neural crest formation + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.