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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of epithelial to mesenchymal transition
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Accession:GO:0010717 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


show annotations for term's descendants           Sort by:
 
regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clasp1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Dag1 dystroglycan 1 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5438719|PMID:22768269)		 UniProt
RGD		 PMID:22768269 GO_REF:0000024 MGI:5438719 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132 		JBrowse link
G Epha3 Eph receptor A3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3703403|PMID:17046737)		 UniProt
RGD		 PMID:17046737 GO_REF:0000024 MGI:3703403 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:16816361) RGD PMID:16816361 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Mcrip1 MAPK regulated co-repressor interacting protein 1 involved_in ISO
ISS		 (PMID:25728771)
GO_REF:0000024		 RGD
UniProt		 PMID:25728771 GO_REF:0000024 NCBI chr10:105,820,656...105,828,146
Ensembl chr10:105,820,656...105,828,271 		JBrowse link
G Phldb1 pleckstrin homology-like domain, family B, member 1 involved_in ISO
IEA		 (PMID:23940118)
GO_REF:0000107		 RGD
Ensembl		 PMID:23940118 GO_REF:0000107 NCBI chr 8:45,003,538...45,051,541
Ensembl chr 8:45,003,538...45,051,522 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467 		JBrowse link
G Pofut2 protein O-fucosyltransferase 2 acts_upstream_of_or_within ISO MGI:3604508|MGI:4127173 (MGI:4838381|PMID:20637190) RGD PMID:20637190 MGI:4838381 NCBI chr20:11,367,073...11,377,788
Ensembl chr20:11,367,096...11,377,743 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA		 (PMID:24887517)
GO_REF:0000107		 RGD
Ensembl		 PMID:24887517 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 involved_in ISO (PMID:20826792) RGD PMID:20826792 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS		 (PMID:17072303)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17072303 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:17072303) RGD PMID:17072303 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
negative regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 involved_in ISO (PMID:23776679) RGD PMID:23776679 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA
ISS		 (PMID:20080667), (PMID:20154697)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20080667 PMID:20154697 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 acts_upstream_of_or_within ISO MGI:5515616 (MGI:5503293|PMID:23580654) RGD PMID:23580654 MGI:5503293 NCBI chr 1:77,546,900...77,558,631
Ensembl chr 1:77,546,900...77,558,630 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO
IEA		 (PMID:29093007)
GO_REF:0000107		 RGD
Ensembl		 PMID:29093007 GO_REF:0000107 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Foxa1 forkhead box A1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20160041)		 Ensembl
RGD		 PMID:20160041 GO_REF:0000107 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa2 forkhead box A2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20160041)		 Ensembl
RGD		 PMID:20160041 GO_REF:0000107 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of ISO (PMID:26451614) RGD PMID:26451614 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Hpn hepsin involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:19843851)		 UniProt
Ensembl
RGD		 PMID:19843851 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Il17rd interleukin 17 receptor D involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr16:2,228,467...2,295,126
Ensembl chr16:2,228,287...2,292,556 		JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in ISO (PMID:24627487) RGD PMID:24627487 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:19443654) RGD PMID:19443654 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693 		JBrowse link
G Mark1 microtubule affinity regulating kinase 1 involved_in ISO (PMID:31281935) RGD PMID:31281935 NCBI chr13:96,450,189...96,555,304
Ensembl chr13:96,451,487...96,555,173 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19293183)		 Ensembl
RGD		 PMID:19293183 GO_REF:0000107 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Ovol2 ovo-like zinc finger 2 involved_in ISO (MGI:5574425|PMID:24735879), (MGI:6284898|PMID:28455959) RGD PMID:24735879 PMID:28455959 MGI:5574425 MGI:6284898 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:20080667) RGD PMID:20080667 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:27919618) RGD PMID:27919618 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 acts_upstream_of_or_within ISO (MGI:5529200|PMID:23983127)
(PMID:23983127)		 RGD PMID:23983127 MGI:5529200 NCBI chr 1:207,139,070...207,167,830
Ensembl chr 1:207,139,112...207,168,616 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:19095296)
GO_REF:0000107		 RGD
Ensembl		 PMID:19095296 GO_REF:0000107 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:19095296) RGD PMID:19095296 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6414689|PMID:25576668)		 UniProt
RGD		 PMID:25576668 GO_REF:0000024 MGI:6414689 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (MGI:3762085|PMID:17823118) RGD PMID:17823118 MGI:3762085 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Trim62 tripartite motif-containing 62 acts_upstream_of_or_within ISO MGI:5538538 (MGI:5585203|PMID:24890125) RGD PMID:24890125 MGI:5585203 NCBI chr 5:141,230,830...141,260,629 JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:20813961 RGD:11568680 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Usf3 upstream transcription factor family member 3 involved_in ISO (PMID:28011713) RGD PMID:28011713 NCBI chr11:56,470,738...56,529,736
Ensembl chr11:56,476,122...56,529,884 		JBrowse link
G Vasn vasorin involved_in ISO (PMID:21170088) RGD PMID:21170088 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Znf750 zinc finger protein 750 involved_in ISO (PMID:32042337) RGD PMID:32042337 NCBI chr10:106,772,162...106,781,186
Ensembl chr10:106,772,669...106,781,200 		JBrowse link
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nog noggin involved_in IEA
ISO		 GO_REF:0000107
(MGI:3783944|PMID:17218603)		 Ensembl
RGD		 PMID:17218603 GO_REF:0000107 MGI:3783944 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
negative regulation of neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fuz fuzzy planar cell polarity protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5498583|PMID:23806618)		 UniProt
RGD		 PMID:23806618 GO_REF:0000024 MGI:5498583 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530 		JBrowse link
positive regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag1 jagged canonical Notch ligand 1 involved_in IGI PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Notch1 notch receptor 1 involved_in IGI PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:5300829|PMID:22186728) RGD PMID:22186728 MGI:5300829 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:21743278 RGD:7243870 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Alx1 ALX homeobox 1 involved_in ISO
ISS		 (PMID:23288509)
GO_REF:0000024		 RGD
UniProt		 PMID:23288509 GO_REF:0000024 NCBI chr 7:38,157,626...38,177,220
Ensembl chr 7:38,147,117...38,177,220 		JBrowse link
G Axin2 axin 2 involved_in ISO
IEA		 (PMID:17072303)
GO_REF:0000107		 RGD
Ensembl		 PMID:17072303 GO_REF:0000107 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO (PMID:19328798) RGD PMID:19328798 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bcl9l BCL9 like involved_in ISO (PMID:19328798) RGD PMID:19328798 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3583785 (MGI:3611958|PMID:16314491)
(PMID:20890042)		 Ensembl
RGD		 PMID:16314491 PMID:20890042 GO_REF:0000107 MGI:3611958 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P23359 (MGI:5502250|PMID:23863481)		 Ensembl
RGD		 PMID:23863481 GO_REF:0000107 MGI:5502250 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO UniProtKB:P21275 (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Col1a1 collagen type I alpha 1 chain involved_in ISO (PMID:20018240) RGD PMID:20018240 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Crb2 crumbs cell polarity complex component 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5296388|PMID:22072575), (MGI:5823085|PMID:27870829)		 CAFA
RGD		 PMID:22072575 PMID:27870829 GO_REF:0000024 MGI:5296388 MGI:5823085 NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO UniProtKB:Q9NX18 (PMID:23983127) RGD PMID:23983127 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5442513|PMID:15734730)		 Ensembl
RGD		 PMID:15734730 GO_REF:0000107 MGI:5442513 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:20154697) RGD PMID:20154697 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:24226523) RGD PMID:24226523 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (PMID:22991501) RGD PMID:22991501 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) involved_in ISO (PMID:21750175)
(MGI:5545971|PMID:21750175)		 RGD PMID:21750175 MGI:5545971 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Glipr2 GLI pathogenesis-related 2 involved_in ISO (PMID:23516513) RGD PMID:23516513 NCBI chr 5:58,170,417...58,200,947
Ensembl chr 5:58,170,425...58,202,272 		JBrowse link
G Hdac2 histone deacetylase 2 IMP RGD PMID:19553350 RGD:9590229 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:25204733)		 Ensembl
RGD		 PMID:25204733 GO_REF:0000107 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:25916550) RGD PMID:25916550 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IMP PMID:23270756 BHF-UCL PMID:23270756 RGD:13210526 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in ISO
IEA		 (PMID:20018240)
GO_REF:0000107		 RGD
Ensembl		 PMID:20018240 GO_REF:0000107 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24239292)		 UniProt
Ensembl
RGD		 PMID:24239292 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067 		JBrowse link
G Mdk midkine involved_in ISO
ISS		 (PMID:18469519)
GO_REF:0000024		 RGD
UniProt		 PMID:18469519 GO_REF:0000024 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:27919618) RGD PMID:27919618 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myocd myocardin involved_in IMP PMID:23270756 BHF-UCL PMID:23270756 RGD:13210526 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:4837019 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Olfm1 olfactomedin 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239 		JBrowse link
G Pdpn podoplanin involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:17046996), (PMID:21376833)		 UniProt
RGD		 PMID:17046996 PMID:21376833 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19158077), (PMID:21307346) RGD PMID:19158077 PMID:21307346 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Sdcbp syndecan binding protein involved_in ISO
ISS		 (PMID:25893292)
GO_REF:0000024		 RGD
UniProt		 PMID:25893292 GO_REF:0000024 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:20527027) RGD PMID:20527027 NCBI chr13:23,274,120...23,280,082
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Smad2 SMAD family member 2 involved_in ISO (MGI:2683382|PMID:14691138) RGD PMID:14691138 MGI:2683382 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (PMID:18505915), (PMID:21307346) RGD PMID:18505915 PMID:21307346 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:2683382|PMID:14691138)		 Ensembl
RGD		 PMID:14691138 GO_REF:0000107 MGI:2683382 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:20018240), (PMID:23288509)
(MGI:4837019|PMID:20890042), (MGI:5548026|PMID:24239292)		 RGD PMID:20018240 PMID:20890042 PMID:23288509 PMID:24239292 MGI:4837019 MGI:5548026 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:5299248|PMID:21983003) RGD PMID:21983003 MGI:5299248 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:17999987), (PMID:18505915)
(MGI:3821807|PMID:18794329)
GO_REF:0000024		 RGD
UniProt		 PMID:17999987 PMID:18505915 PMID:18794329 GO_REF:0000024 MGI:3821807 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17999987), (PMID:18505915)		 AgBase
RGD		 PMID:17999987 PMID:18505915 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2683382|PMID:14691138)
(PMID:18505915), (PMID:18718461)		 AgBase
RGD		 PMID:14691138 PMID:18505915 PMID:18718461 GO_REF:0000024 MGI:2683382 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO UniProtKB:P10600 (MGI:3820811|PMID:18718461) RGD PMID:18718461 MGI:3820811 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (PMID:26459119) RGD PMID:26459119 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:18297062)
(MGI:4838344|PMID:20804746), (MGI:5284765|PMID:18297062), (MGI:5284780|PMID:17332324)		 RGD PMID:17332324 PMID:18297062 PMID:20804746 MGI:4838344 MGI:5284765 MGI:5284780 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 involved_in ISO (PMID:18227151) RGD PMID:18227151 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (MGI:4940410|PMID:21317240) RGD PMID:21317240 MGI:4940410 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677 		JBrowse link
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3610266|PMID:16140292)		 Ensembl
RGD		 PMID:16140292 GO_REF:0000107 MGI:3610266 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Eng endoglin involved_in ISO (MGI:4368063|PMID:19703439) RGD PMID:19703439 MGI:4368063 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA		 (MGI:3820811|PMID:18718461)
GO_REF:0000107		 RGD
Ensembl		 PMID:18718461 GO_REF:0000107 MGI:3820811 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 NOT|involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 NOT|involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    regulation of biological process 12866
      regulation of cellular process 12336
        regulation of cell differentiation 1719
          regulation of epithelial to mesenchymal transition 97
            negative regulation of epithelial to mesenchymal transition + 35
            positive regulation of epithelial to mesenchymal transition + 50
            regulation of cardiac epithelial to mesenchymal transition + 11
            regulation of neural crest formation + 2
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            animal organ development 4130
              mesenchyme development 301
                mesenchymal cell differentiation 242
                  epithelial to mesenchymal transition 158
                    regulation of epithelial to mesenchymal transition 97
                      negative regulation of epithelial to mesenchymal transition + 35
                      positive regulation of epithelial to mesenchymal transition + 50
                      regulation of cardiac epithelial to mesenchymal transition + 11
                      regulation of neural crest formation + 2
paths to the root