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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of collagen metabolic process
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Accession:GO:0010712 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
Synonyms:exact_synonym: regulation of collagen metabolism


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regulation of collagen metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:2135670 (MGI:4437389|PMID:20053668) RGD PMID:20053668 MGI:4437389 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Mfap4 microfibril associated protein 4 involved_in ISO (PMID:22355679) RGD PMID:22355679 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
JBrowse link
negative regulation of collagen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor IMP RGD PMID:9535419 RGD:2316149 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:21872885 RGD:7245949 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Cygb cytoglobin IDA RGD PMID:20719976 RGD:9685174 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IMP RGD PMID:25840911 RGD:12904676 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 IMP RGD PMID:15521018 RGD:15045602 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IMP RGD PMID:19204184 RGD:9685562 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Fn1 fibronectin 1 IMP RGD PMID:15980055 RGD:1625201 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:26880260 RGD:13504840 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:12419823) RGD PMID:12419823 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor involved_in ISO (PMID:12419823) RGD PMID:12419823 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Nppc natriuretic peptide C IDA RGD PMID:12746286 RGD:1580115 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IMP RGD PMID:15980055 RGD:1625201 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IMP RGD PMID:17346664 RGD:2324888 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:16202214 RGD:8553021 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IMP RGD PMID:22012077 RGD:9850086 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 IMP RGD PMID:22012077 RGD:9850086 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
negative regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
positive regulation of collagen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IMP RGD PMID:28274926 RGD:13506828 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17720811)
Ensembl
UniProt
RGD
PMID:17720811 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Cbx8 chromobox 8 IMP RGD PMID:23572236 RGD:9586727 NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IDA RGD PMID:8663511 RGD:8549527 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccn2 cellular communication network factor 2 IMP RGD PMID:19570811 RGD:2314490 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in ISO
ISS
(PMID:25310401)
GO_REF:0000024
RGD
UniProt
PMID:25310401 GO_REF:0000024 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
JBrowse link
G Dicer1 dicer 1 ribonuclease III IMP RGD PMID:24337369 RGD:150340618 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Eng endoglin IMP RGD PMID:20156938 RGD:7257540 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:18292803 RGD:2312266 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G F2 coagulation factor II involved_in IEA
ISO
GO_REF:0000107
(PMID:9639571)
Ensembl
RGD
PMID:9639571 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:9639571)
Ensembl
UniProt
RGD
PMID:9639571 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO (MGI:1335697|PMID:10208865) RGD PMID:10208865 MGI:1335697 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Il18 interleukin 18 IDA RGD PMID:20644901 RGD:4889158 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Itga2 integrin subunit alpha 2 IMP RGD PMID:10867645 RGD:2307406 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Larp6 La ribonucleoprotein 6, translational regulator involved_in ISO (PMID:21746880) RGD PMID:21746880 NCBI chr 8:61,183,744...61,205,548
Ensembl chr 8:61,184,116...61,205,535
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 IMP RGD PMID:9607192 RGD:10412058 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Mir21 microRNA 21 IDA RGD PMID:29084974 RGD:41404715 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mkx mohawk homeobox acts_upstream_of_or_within ISO MGI:4461224 (MGI:4457966|PMID:20498044) RGD PMID:20498044 MGI:4457966 NCBI chr17:55,077,073...55,156,877
Ensembl chr17:55,077,540...55,156,124
JBrowse link
G Myb MYB proto-oncogene, transcription factor IMP RGD PMID:15534927 RGD:11532676 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Pdgfb platelet derived growth factor subunit B IMP RGD PMID:15358192 RGD:10449487 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IMP RGD PMID:15978205 RGD:2292205 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Prdx5 peroxiredoxin 5 involved_in ISO (PMID:15276323) RGD PMID:15276323 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19158077) RGD PMID:19158077 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:4413438|PMID:18802027), (MGI:5294534|PMID:19362560) RGD PMID:18802027 PMID:19362560 MGI:4413438 MGI:5294534 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626
JBrowse link
G Serpinb7 serpin family B member 7 IMP RGD PMID:21945418 RGD:7207383 NCBI chr13:23,369,830...23,442,205
Ensembl chr13:23,395,671...23,442,205
JBrowse link
G Serpine1 serpin family E member 1 IMP RGD PMID:15828931 RGD:13208547 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:17958745)
(MGI:4453296|PMID:18436805)
RGD PMID:17958745 PMID:18436805 MGI:4453296 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Suco SUN domain containing ossification factor involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4452525|PMID:20440000)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20440000 GO_REF:0000024 GO_REF:0000107 MGI:4452525 NCBI chr13:74,192,808...74,257,896
Ensembl chr13:74,193,573...74,257,896
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in IMP
ISO
ISS
(MGI:4820704|PMID:19734317)
GO_REF:0000024
RNAcentral:URS000024463E_9606 (PMID:11158066), (PMID:19734317), (PMID:22269326), (PMID:25310401)
RGD
UniProt
PMID:11158066 PMID:19734317 PMID:22269326 PMID:25310401 PMID:26923362 GO_REF:0000024 MGI:4820704, RGD:11073665 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS
(PMID:11158066)
GO_REF:0000024
RGD
AgBase
PMID:11158066 GO_REF:0000024 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Ucn urocortin IDA RGD PMID:11087261 RGD:1642796 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:17184580 PMID:18475149 RGD:2306814, RGD:2306811 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
JBrowse link
G Vim vimentin involved_in IEA
ISO
GO_REF:0000107
(PMID:21746880)
Ensembl
RGD
PMID:21746880 GO_REF:0000107 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Wnt4 Wnt family member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:17720811)
Ensembl
RGD
PMID:17720811 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
positive regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236 (MGI:4397742|PMID:19834056) RGD PMID:19834056 MGI:4397742 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:20666777) RGD PMID:20666777 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
positive regulation of collagen metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Retn resistin IMP RGD PMID:20795947 RGD:7207234 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fap fibroblast activation protein, alpha involved_in ISO (PMID:10455171) RGD PMID:10455171 NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545
JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:10455171)
UniProt
Ensembl
RGD
PMID:10455171 GO_REF:0000024 GO_REF:0000107 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      regulation of metabolic process 6740
        regulation of collagen metabolic process 59
          negative regulation of collagen metabolic process + 18
          positive regulation of collagen metabolic process + 37
          regulation of collagen biosynthetic process + 51
          regulation of collagen catabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of metabolic process 6740
          regulation of collagen metabolic process 59
            negative regulation of collagen metabolic process + 18
            positive regulation of collagen metabolic process + 37
            regulation of collagen biosynthetic process + 51
            regulation of collagen catabolic process + 5
paths to the root