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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of muscle cell apoptotic process
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Accession:GO:0010656 term browser browse the term
Definition:Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
Synonyms:narrow_synonym: negative regulation of muscle cell apoptosis



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negative regulation of muscle cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IDA RGD PMID:16891268 RGD:2325292 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISO
ISS
(PMID:23578768)
GO_REF:0000024
RGD
UniProt
PMID:23578768 GO_REF:0000024 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Cav1 caveolin 1 IMP RGD PMID:18039791 RGD:2289114 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IMP RGD PMID:14654373 RGD:2289997 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:12396617 RGD:728858 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Igf1 insulin-like growth factor 1 IMP RGD PMID:16699953 RGD:12904920 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IMP RGD PMID:19507001 RGD:2311507 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Lifr LIF receptor subunit alpha IMP RGD PMID:15927854 RGD:1581857 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IMP RGD PMID:15089039 RGD:1625255 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:12668584 RGD:1642633 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Smad1 SMAD family member 1 IEP RGD PMID:11408477 RGD:1643239 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Tbx1 T-box transcription factor 1 IMP RGD PMID:31982878 RGD:155882591 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(MGI:5142149|PMID:21616078)
UniProt
RGD
PMID:21616078 GO_REF:0000024 MGI:5142149 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
negative regulation of cardiac muscle cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot1 acyl-CoA thioesterase 1 IMP RGD PMID:23226270 RGD:13831128 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 IMP RGD PMID:25117440 RGD:11552604 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3050453|MGI:3663625 (PMID:17450150)
Ensembl
RGD
PMID:17450150 GO_REF:0000107 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:17450150) RGD PMID:17450150 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in IMP PMID:26692938 BHF-UCL PMID:26692938 RGD:12911011 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:14596792 RGD:11341703 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO RNAcentral:URS000006FDD4_10090 (MGI:5780531|PMID:25590961) RGD PMID:25590961 MGI:5780531 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gch1 GTP cyclohydrolase 1 IMP RGD PMID:30690003 RGD:401717569 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Ghrh growth hormone releasing hormone IMP RGD PMID:20133784 PMID:19293247 RGD:2325186, RGD:2325187 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G H19 H19 imprinted maternally expressed transcript IMP RGD PMID:27796346 PMID:31975412 RGD:156430325, RGD:156430334 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:4413411|PMID:19008477)
Ensembl
RGD
PMID:19008477 GO_REF:0000107 MGI:4413411 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:2447620 (PMID:20382855) RGD PMID:20382855 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:22426029 RGD:10402789 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:21958194 RGD:10059326 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb6 heat shock protein family B (small) member 6 involved_in IDA PMID:15105294 UniProt PMID:15105294 RGD:12050134 NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071
JBrowse link
G Ilk integrin-linked kinase IMP RGD PMID:16170337 RGD:2302069 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:23796350 RGD:8694332 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Kifap3 kinesin-associated protein 3 acts_upstream_of_or_within ISO MGI:3613572 (PMID:10793158) RGD PMID:10793158 NCBI chr13:76,127,702...76,264,654
Ensembl chr13:76,127,696...76,264,650
JBrowse link
G Mdk midkine involved_in ISO
IEA
ISS
(PMID:19060126)
GO_REF:0000107
(MGI:3761216|PMID:17015789), (MGI:3837261|PMID:19060126)
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17015789 PMID:19060126 GO_REF:0000024 GO_REF:0000107 MGI:3761216 MGI:3837261 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:28483668 RGD:12910717 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mir145 microRNA 145 involved_in ISO (PMID:23028672) RGD PMID:23028672 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir21 microRNA 21 IMP RGD PMID:19336275 RGD:41404719 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir210 microRNA 210 IMP RGD PMID:28661226 RGD:155260328 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mir222 microRNA 222 IMP RGD PMID:25863248 RGD:152025190 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mir223 microRNA 223 IDA RGD PMID:29608885 RGD:21408565 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir30e microRNA 30e IMP RGD PMID:27633839 RGD:401827149 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
JBrowse link
G Mir494 microRNA 494 IDA RGD PMID:30783439 RGD:150527846 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Myocd myocardin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3773717 (PMID:19850880)
Ensembl
RGD
PMID:19850880 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 IMP RGD PMID:23453443 RGD:10412713 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3784761|PMID:11889119)
(PMID:11889119)
Ensembl
RGD
PMID:11889119 GO_REF:0000107 MGI:3784761 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3710289|PMID:16505176)
Ensembl
RGD
PMID:16505176 GO_REF:0000107 MGI:3710289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Npm1 nucleophosmin 1 IMP RGD PMID:21444791 RGD:11535018 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISS
IMP
ISO
GO_REF:0000024
PMID:20181828
(PMID:20181828)
UniProt
RGD
PMID:20181828 PMID:20181828 GO_REF:0000024, RGD:14390062 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
JBrowse link
G Pax8 paired box 8 involved_in ISO (MGI:5908333|PMID:22453009) RGD PMID:22453009 MGI:5908333 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 IMP RGD PMID:23647599 RGD:10448278 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA
(MGI:3849539|PMID:19429709)
GO_REF:0000107
RGD
Ensembl
PMID:19429709 GO_REF:0000107 MGI:3849539 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO (PMID:23426265) RGD PMID:23426265 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
JBrowse link
G Qki QKI, KH domain containing RNA binding IMP RGD PMID:22178871 RGD:10045994 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Ralgdsl2 ral guanine nucleotide dissociation stimulator like 2 acts_upstream_of_or_within ISO (PMID:24069211) RGD PMID:24069211 NCBI chr20:4,948,495...4,956,774
Ensembl chr20:4,948,497...4,969,911
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 IMP RGD PMID:18276108 RGD:9835371 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO (PMID:17251350) RGD PMID:17251350 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:20089851 RGD:2316169 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
JBrowse link
G Sirt5 sirtuin 5 IMP RGD PMID:24192575 RGD:9586058 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101
JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:22564366 RGD:9681467 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799
JBrowse link
negative regulation of smooth muscle cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a acts_upstream_of_or_within ISO (PMID:19508861) RGD PMID:19508861 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:15534879) RGD PMID:15534879 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Dipk2a divergent protein kinase domain 2A involved_in
acts_upstream_of_or_within
ISO (PMID:24269490) RGD PMID:24269490 NCBI chr 8:95,070,695...95,089,815
Ensembl chr 8:95,030,279...95,089,815
JBrowse link
G Edn1 endothelin 1 IDA RGD PMID:16857764 RGD:4892596 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Esr1 estrogen receptor 1 involved_in IMP PMID:21808025 UniProt PMID:21808025 RGD:13432273 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 involved_in ISO
IEA
RNAcentral:URS00003E47B1_9606 (PMID:32151690)
GO_REF:0000107
RGD
Ensembl
PMID:32151690 GO_REF:0000107 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:21557011 RGD:10045551 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IMP
(PMID:16942485)
PMID:20724525
RGD PMID:16942485 PMID:20724525 RGD:401901210 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in ISO (PMID:15271658) RGD PMID:15271658 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Lypd3 Ly6/Plaur domain containing 3 involved_in ISO RNAcentral:URS00003E47B1_9606 (PMID:32151690) RGD PMID:32151690 NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20724525 UniProt PMID:20724525 RGD:401901210 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in IMP PMID:20724525 UniProt PMID:20724525 RGD:401901210 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 acts_upstream_of_or_within ISO MGI:3037444 (PMID:19153266) RGD PMID:19153266 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region IMP RGD PMID:15247148 RGD:2306423 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:20724525) RGD PMID:20724525 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
negative regulation of striated muscle cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:19085932)
MGI:3530294 (PMID:16936253)
GO_REF:0000033
RGD
GO_Central
PMID:16936253 PMID:19085932 GO_REF:0000033 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:19505369 RGD:5508691 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Naca nascent polypeptide associated complex subunit alpha involved_in ISO (MGI:4867362|PMID:21071677) RGD PMID:21071677 MGI:4867362 NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO (MGI:5573029|PMID:24312627) RGD PMID:24312627 MGI:5573029 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
negative regulation of vascular associated smooth muscle cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IMP RGD PMID:24999019 RGD:11567225 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Dnmt1 DNA methyltransferase 1 involved_in ISO
IEA
(PMID:27021683)
GO_REF:0000107
RGD
Ensembl
PMID:27021683 GO_REF:0000107 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase IMP RGD PMID:28404743 RGD:13792653 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
(PMID:26166810)
GO_REF:0000107
RGD
Ensembl
PMID:26166810 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:27640178) RGD PMID:27640178 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:28522568) RGD PMID:28522568 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:22886504) RGD PMID:22886504 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Slc7a5 solute carrier family 7 member 5 IDA RGD PMID:29687865 RGD:151357004 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    negative regulation of biological process 5757
      negative regulation of cellular process 5391
        negative regulation of programmed cell death 1096
          negative regulation of apoptotic process 1058
            negative regulation of muscle cell apoptotic process 83
              negative regulation of smooth muscle cell apoptotic process + 23
              negative regulation of striated muscle cell apoptotic process + 50
Path 2
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cell death 2201
        programmed cell death 2201
          apoptotic process 2120
            muscle cell apoptotic process 147
              regulation of muscle cell apoptotic process 137
                negative regulation of muscle cell apoptotic process 83
                  negative regulation of smooth muscle cell apoptotic process + 23
                  negative regulation of striated muscle cell apoptotic process + 50
paths to the root