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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lamellipodium assembly
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Accession:GO:0010591 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:related_synonym: regulation of lamellipodium biogenesis



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regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin3 bridging integrator 3 acts_upstream_of_or_within IMP (MGI:5517720|PMID:23872330) MGI PMID:23872330 MGI:5517720 NCBI chr14:70,100,089...70,137,964
Ensembl chr14:70,100,105...70,138,206
JBrowse link
G Capzb capping protein (actin filament) muscle Z-line, beta involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:139,192,899...139,291,820
Ensembl chr 4:139,192,899...139,291,818
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:137,319,696...137,357,759
Ensembl chr 4:137,319,696...137,357,720
JBrowse link
G Dmtn dematin actin binding protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:70,602,184...70,636,048
Ensembl chr14:70,601,263...70,636,048
JBrowse link
G Epha2 Eph receptor A2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:141,301,221...141,329,384
Ensembl chr 4:141,301,240...141,329,384
JBrowse link
G Fer fer (fms/fps related) protein kinase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:63,862,073...64,146,519
Ensembl chr17:63,863,062...64,139,496
JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Twf1 twinfilin actin binding protein 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr15:94,577,948...94,589,884
Ensembl chr15:94,577,951...94,589,889
JBrowse link
G Twf2 twinfilin actin binding protein 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:106,203,108...106,215,387
Ensembl chr 9:106,203,108...106,215,389
JBrowse link
G Was Wiskott-Aldrich syndrome involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:8,081,466...8,090,491
Ensembl chr  X:8,081,453...8,090,498
JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family member 3 involved_in IMP (MGI:6508508|PMID:26428302) ARUK-UCL PMID:26428302 MGI:6508508 NCBI chr11:95,830,072...95,842,476
Ensembl chr11:95,830,074...95,842,476
JBrowse link
G Cfl1 cofilin 1, non-muscle involved_in ISO RGD
MGI
PMID:24093776 GO_REF:0000096 MGI:4417868 RGD:11570550 NCBI chr19:5,490,455...5,494,031
Ensembl chr19:5,490,455...5,495,201
JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:22,951,072...22,961,659
Ensembl chr16:22,951,072...22,961,656
JBrowse link
G Plxnb3 plexin B3 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr  X:73,756,556...73,772,510
Ensembl chr  X:73,757,090...73,772,514
JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:47,981,291...48,307,735
Ensembl chr 5:47,983,138...48,307,733
JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl interactor 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:60,405,768...60,481,945
Ensembl chr 1:60,409,619...60,481,158
JBrowse link
G Actr2 ARP2 actin-related protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:20,062,304...20,112,951
Ensembl chr11:20,062,304...20,112,913
JBrowse link
G Actr3 ARP3 actin-related protein 3 involved_in ISO MGI
RGD
PMID:18256280 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:2306202 NCBI chr 1:125,392,905...125,435,727
Ensembl chr 1:125,392,905...125,435,727
JBrowse link
G Akirin1 akirin 1 involved_in IMP
IBA
(MGI:3850794|PMID:19406121)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:19406121 PMID:21873635 MGI:3850794 MGI:6201960 NCBI chr 4:123,735,195...123,750,299
Ensembl chr 4:123,734,559...123,750,345
JBrowse link
G Aqp1 aquaporin 1 involved_in ISO RGD
MGI
PMID:19539607 GO_REF:0000096 MGI:4417868 RGD:2316079 NCBI chr 6:55,336,299...55,348,555
Ensembl chr 6:55,336,432...55,348,555
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 involved_in ISO MGI
RGD
PMID:15252126 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:2306210 NCBI chr 1:74,236,490...74,268,209
Ensembl chr 1:74,236,084...74,268,209
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide involved_in ISO RGD
MGI
PMID:20671235 GO_REF:0000096 MGI:4417868 RGD:11341707 NCBI chr  X:106,027,224...106,128,161
Ensembl chr  X:106,027,276...106,124,926
JBrowse link
G Auts2 autism susceptibility candidate 2 involved_in IMP (MGI:5908783|PMID:25533347) UniProt PMID:25533347 MGI:5908783 NCBI chr 5:131,437,333...132,543,220
Ensembl chr 5:131,437,333...132,543,344
JBrowse link
G Avil advillin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:127,000,065...127,020,994
Ensembl chr10:127,000,709...127,020,994
JBrowse link
G Brk1 BRICK1, SCAR/WAVE actin-nucleating complex subunit involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:113,604,772...113,616,951
Ensembl chr 6:113,604,772...113,616,951
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:105,686,010...105,698,195
Ensembl chr 8:105,686,274...105,698,187
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:137,319,696...137,357,759
Ensembl chr 4:137,319,696...137,357,720
JBrowse link
G Cfl1 cofilin 1, non-muscle involved_in ISO RGD
MGI
PMID:15252126 GO_REF:0000096 MGI:4417868 RGD:2306210 NCBI chr19:5,490,455...5,494,031
Ensembl chr19:5,490,455...5,495,201
JBrowse link
G Clrn1 clarin 1 acts_upstream_of_or_within ISO (MGI:4353469|PMID:19423712) MGI PMID:19423712 MGI:4353469 NCBI chr 3:58,844,028...58,885,212
Ensembl chr 3:58,844,028...58,885,340
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:55,842,022...55,932,633
Ensembl chr 7:55,841,745...55,932,602
JBrowse link
G Dnm2 dynamin 2 involved_in ISO RGD
MGI
PMID:14617821 GO_REF:0000096 MGI:4417868 RGD:9685179 NCBI chr 9:21,424,908...21,507,759
Ensembl chr 9:21,424,908...21,507,759
JBrowse link
G Frmd7 FERM domain containing 7 acts_upstream_of_or_within IDA (MGI:5546532|PMID:23967341) MGI PMID:23967341 MGI:5546532 NCBI chr  X:50,892,643...50,943,619
Ensembl chr  X:50,895,180...50,942,710
JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:142,960,355...142,973,189
Ensembl chr 5:142,960,343...142,973,185
JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO RGD
MGI
PMID:24166750 GO_REF:0000096 MGI:4417868 RGD:9681442 NCBI chr 1:91,928,779...92,195,702
Ensembl chr 1:91,928,779...92,195,699
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 ISO RGD PMID:15302889 RGD:2316937 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728
JBrowse link
G Mstn myostatin involved_in IMP (MGI:3850794|PMID:19406121) UniProt PMID:19406121 MGI:3850794 NCBI chr 1:53,061,640...53,068,079
Ensembl chr 1:53,061,640...53,068,079
JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within IDA (MGI:3510095|PMID:15467718) MGI PMID:15467718 MGI:3510095 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Nckap1 NCK-associated protein 1 involved_in ISO
IDA
(MGI:5897521|PMID:27927633) MGI
BHF-UCL
PMID:27927633 GO_REF:0000096 MGI:4834177 MGI:5897521 NCBI chr 2:80,500,512...80,581,182
Ensembl chr 2:80,500,512...80,581,380
JBrowse link
G Ocln occludin involved_in ISO (PMID:20152177) ARUK-UCL PMID:20152177 NCBI chr13:100,496,504...100,552,718
Ensembl chr13:100,496,507...100,552,718
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IDA (MGI:6450670|PMID:11038173) BHF-UCL PMID:11038173 MGI:6450670 NCBI chr13:101,680,761...101,768,217
Ensembl chr13:101,680,563...101,768,217
JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:38,481,034...38,785,105
Ensembl chr19:38,481,109...38,785,030
JBrowse link
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within
involved_in
ISO (MGI:3510095|PMID:15467718) MGI
RGD
PMID:12105187 PMID:15467718 GO_REF:0000096 MGI:3510095 MGI:4417868 MGI:4834177 RGD:1299247 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO
IMP
(MGI:4355276|PMID:19625648) MGI
UniProt
PMID:19625648 GO_REF:0000096 MGI:4355276 MGI:4834177 NCBI chr15:78,559,169...78,572,783
Ensembl chr15:78,559,167...78,572,783
JBrowse link
G Twf2 twinfilin actin binding protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:106,203,108...106,215,387
Ensembl chr 9:106,203,108...106,215,389
JBrowse link
G Wasf2 WASP family, member 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:133,130,531...133,199,748
Ensembl chr 4:133,130,505...133,199,756
JBrowse link
G Wnt1 wingless-type MMTV integration site family, member 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:98,789,857...98,793,830
Ensembl chr15:98,789,857...98,793,837
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28615
    cellular process 17655
      regulation of cellular process 12145
        regulation of cellular component biogenesis 1052
          regulation of cell projection assembly 238
            regulation of plasma membrane bounded cell projection assembly 235
              regulation of lamellipodium assembly 42
                negative regulation of lamellipodium assembly 5
                positive regulation of lamellipodium assembly 31
Path 2
Term Annotations click to browse term
  biological_process 28615
    cellular process 17655
      cellular component organization or biogenesis 6530
        cellular component organization 6337
          cell projection organization 1774
            plasma membrane bounded cell projection organization 1730
              lamellipodium organization 96
                lamellipodium assembly 76
                  regulation of lamellipodium assembly 42
                    negative regulation of lamellipodium assembly 5
                    positive regulation of lamellipodium assembly 31
paths to the root