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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lamellipodium assembly
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Accession:GO:0010591 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:related_synonym: regulation of lamellipodium biogenesis



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regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC097637.1 novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 Ensembl chr 3:52,221,081...52,231,190 JBrowse link
G BIN3 bridging integrator 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5517720|PMID:23872330) Ensembl
Ensembl
MGI
PMID:23872330 GO_REF:0000107 MGI:5517720 NCBI chr 8:22,620,418...22,669,148
Ensembl chr 8:22,620,418...22,669,148
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
JBrowse link
G CDC42 cell division cycle 42 involved_in IGI (PMID:8625410) CAFA
CAFA
PMID:8625410 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,025,511...22,101,360
JBrowse link
G DMTN dematin actin binding protein involved_in IMP (PMID:10565303) UniProt
UniProt
PMID:10565303 NCBI chr 8:22,048,931...22,082,525
Ensembl chr 8:22,048,995...22,082,527
JBrowse link
G EPHA2 EPH receptor A2 involved_in IMP (PMID:19573808) UniProt
UniProt
PMID:19573808 NCBI chr 1:16,124,337...16,156,104
Ensembl chr 1:16,124,337...16,156,069
JBrowse link
G FER FER tyrosine kinase involved_in IDA (PMID:19738202) UniProt
UniProt
PMID:19738202 NCBI chr 5:108,746,085...109,196,841
Ensembl chr 5:108,747,841...109,196,841
JBrowse link
G RAC1 Rac family small GTPase 1 involved_in IGI (PMID:8625410) CAFA
CAFA
PMID:8625410 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr12:43,793,723...43,806,317
Ensembl chr12:43,793,723...43,806,328
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 3:52,228,612...52,239,158
Ensembl chr 3:52,228,612...52,246,788
JBrowse link
G WAS WASP actin nucleation promoting factor involved_in IGI (PMID:8625410) CAFA
CAFA
PMID:8625410 NCBI chr  X:48,683,753...48,691,427
Ensembl chr  X:48,676,596...48,691,427
JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI3 ABI family member 3 involved_in ISS
IEA
ARUK-UCL
ARUK-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:49,210,582...49,223,225
Ensembl chr17:49,210,411...49,223,225
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:24093776 RGD:11570550 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G HRG histidine rich glycoprotein involved_in IDA (PMID:16489009) UniProt
UniProt
PMID:16489009 NCBI chr 3:186,665,975...186,678,235
Ensembl chr 3:186,660,216...186,678,234
JBrowse link
G PLXNB3 plexin B3 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr  X:153,764,249...153,779,341
Ensembl chr  X:153,764,196...153,779,346
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IDA (PMID:16439689) UniProt
UniProt
PMID:16439689 NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561
JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in IDA (PMID:21107423) ARUK-UCL
ARUK-UCL
PMID:21107423 NCBI chr 2:203,325,013...203,432,169
Ensembl chr 2:203,328,280...203,447,728
JBrowse link
G ACTR2 actin related protein 2 involved_in IDA (PMID:29058690) UniProt
UniProt
PMID:29058690 NCBI chr 2:65,227,831...65,271,253
Ensembl chr 2:65,227,788...65,271,253
JBrowse link
G ACTR3 actin related protein 3 involved_in IDA
ISO
(PMID:29058690) UniProt
UniProt
RGD
PMID:18256280 PMID:29058690 RGD:2306202 NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596
JBrowse link
G AKIRIN1 akirin 1 involved_in IBA
IEA
ISS
(PMID:21873635) GO_Central
Ensembl
GO_Central
UniProt
UniProt
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:38,991,276...39,006,059
Ensembl chr 1:38,991,276...39,006,059
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO RGD PMID:19539607 RGD:2316079 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 involved_in IMP
ISO
(PMID:18560548) UniProt
UniProt
RGD
PMID:15252126 PMID:18560548 RGD:2306210 NCBI chr 2:218,217,138...218,254,348
Ensembl chr 2:218,217,141...218,254,356
JBrowse link
G ATP7A ATPase copper transporting alpha involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:20671235 GO_REF:0000107 RGD:11341707 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395
JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 7:69,598,475...70,793,506
Ensembl chr 7:69,598,296...70,793,506
JBrowse link
G AVIL advillin involved_in IMP (PMID:29058690) UniProt
UniProt
PMID:29058690 NCBI chr12:57,797,376...57,818,734
Ensembl chr12:57,797,376...57,818,734
JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in IMP
IDA
(PMID:18560548)
(PMID:21107423)
UniProt
UniProt
ARUK-UCL
ARUK-UCL
PMID:18560548 PMID:21107423 NCBI chr 3:10,115,675...10,127,190
Ensembl chr 3:10,115,675...10,127,190
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IDA (PMID:26466680) UniProt
UniProt
PMID:26466680 NCBI chr16:67,645,004...67,657,569
Ensembl chr16:67,644,988...67,657,569
JBrowse link
G CDC42 cell division cycle 42 involved_in IMP (PMID:8625410) CAFA
CAFA
PMID:8625410 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,025,511...22,101,360
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:15252126 RGD:2306210 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CLRN1 clarin 1 acts_upstream_of_or_within IDA (PMID:19423712) MGI
MGI
PMID:19423712 NCBI chr 3:150,926,163...150,972,999
Ensembl chr 3:150,926,163...150,972,727
JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in IDA (PMID:21107423) ARUK-UCL
ARUK-UCL
PMID:21107423 NCBI chr15:22,867,052...22,980,898
Ensembl chr15:22,867,052...22,981,063
JBrowse link
G DNM2 dynamin 2 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:14617821 GO_REF:0000107 RGD:9685179 NCBI chr19:10,718,079...10,831,903
Ensembl chr19:10,718,055...10,833,488
JBrowse link
G FRMD7 FERM domain containing 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5546532|PMID:23967341) Ensembl
Ensembl
MGI
PMID:23967341 GO_REF:0000107 MGI:5546532 NCBI chr  X:132,074,926...132,128,020
Ensembl chr  X:132,076,990...132,128,020
JBrowse link
G FSCN1 fascin actin-bundling protein 1 involved_in IDA (PMID:9571235) UniProt
UniProt
PMID:9571235 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655
JBrowse link
G HDAC4 histone deacetylase 4 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:24166750 GO_REF:0000107 RGD:9681442 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:15302889 RGD:2316937 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
JBrowse link
G MSTN myostatin involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:190,055,700...190,062,729
Ensembl chr 2:190,055,700...190,062,729
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3510095|PMID:15467718) Ensembl
Ensembl
MGI
PMID:15467718 GO_REF:0000107 MGI:3510095 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G NCKAP1 NCK associated protein 1 involved_in ISS
IMP
IDA
(PMID:18560548)
(PMID:21107423)
BHF-UCL
BHF-UCL
UniProt
ARUK-UCL
ARUK-UCL
UniProt
PMID:18560548 PMID:21107423 GO_REF:0000024 NCBI chr 2:182,909,115...183,038,457
Ensembl chr 2:182,909,115...183,038,858
JBrowse link
G OCLN occludin involved_in ISS ARUK-UCL
ARUK-UCL
GO_REF:0000024 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 3:179,148,114...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 5:68,215,737...68,301,821
Ensembl chr 5:68,215,756...68,301,821
JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in IMP (PMID:29058690) UniProt
UniProt
PMID:29058690 NCBI chr10:93,993,931...94,332,823
Ensembl chr10:93,993,931...94,332,823
JBrowse link
G RAC1 Rac family small GTPase 1 involved_in
acts_upstream_of_or_within
IMP
IDA
ISO
(PMID:19625648), (PMID:8625410)
(PMID:15467718)
UniProt
MGI
UniProt
MGI
RGD
PMID:8625410 PMID:12105187 PMID:15467718 PMID:19625648 RGD:1299247 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IMP
IEA
(PMID:19625648) UniProt
UniProt
Ensembl
PMID:19625648 GO_REF:0000107 NCBI chr22:37,225,270...37,244,269
Ensembl chr22:37,225,270...37,244,448
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in IMP (PMID:17910947) BHF-UCL
BHF-UCL
PMID:17910947 NCBI chr 3:52,228,612...52,239,158
Ensembl chr 3:52,228,612...52,246,788
JBrowse link
G WASF2 WASP family member 2 involved_in IMP (PMID:18560548), (PMID:21107423) UniProt
UniProt
PMID:18560548 PMID:21107423 NCBI chr 1:27,404,230...27,490,167
Ensembl chr 1:27,404,230...27,490,167
JBrowse link
G WNT1 Wnt family member 1 involved_in IMP (PMID:19756656) BHF-UCL
BHF-UCL
PMID:19756656 NCBI chr12:48,978,322...48,982,620
Ensembl chr12:48,978,322...48,982,620
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18661
    cellular process 17546
      regulation of cellular process 11965
        regulation of cellular component biogenesis 1086
          regulation of cell projection assembly 244
            regulation of plasma membrane bounded cell projection assembly 241
              regulation of lamellipodium assembly 44
                negative regulation of lamellipodium assembly 5
                positive regulation of lamellipodium assembly 32
Path 2
Term Annotations click to browse term
  biological_process 18661
    cellular process 17546
      cellular component organization or biogenesis 6930
        cellular component organization 6732
          cell projection organization 1816
            plasma membrane bounded cell projection organization 1774
              lamellipodium organization 98
                lamellipodium assembly 78
                  regulation of lamellipodium assembly 44
                    negative regulation of lamellipodium assembly 5
                    positive regulation of lamellipodium assembly 32
paths to the root