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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lamellipodium assembly
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Accession:GO:0010591 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:related_synonym: regulation of lamellipodium biogenesis



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regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN3 bridging integrator 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5517720|PMID:23872330) Ensembl
Ensembl
MGI
PMID:23872330 GO_REF:0000107 MGI:5517720 NCBI chr25:34,615,683...34,659,739
Ensembl chr25:34,615,249...34,659,755
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 2:79,182,668...79,311,529
Ensembl chr 2:79,181,851...79,311,518
JBrowse link
G DMTN dematin actin binding protein involved_in ISO (PMID:10565303) UniProt PMID:10565303 NCBI chr25:35,163,867...35,188,761
Ensembl chr25:35,165,876...35,176,754
JBrowse link
G EPHA2 EPH receptor A2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:81,534,130...81,561,722
Ensembl chr 2:81,534,125...81,561,725
JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999
JBrowse link
G LOC403934 cell division cycle 42 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 2:77,153,276...77,169,947
Ensembl chr 2:77,153,095...77,199,211
JBrowse link
G RAC1 Rac family small GTPase 1 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 6:11,726,259...11,758,532
Ensembl chr 6:11,655,494...11,757,216
JBrowse link
G TLR9 toll like receptor 9 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr27:10,281,249...10,295,550
Ensembl chr27:10,246,746...10,293,543
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr20:37,529,322...37,539,955
Ensembl chr20:37,529,401...37,539,957
JBrowse link
G WAS WASP actin nucleation promoting factor involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr  X:41,882,240...41,890,053
Ensembl chr  X:41,882,875...41,890,058
JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI3 ABI family member 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:25,374,823...25,385,016
Ensembl chr 9:25,374,525...25,385,003
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:24093776 RGD:11570550 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212
JBrowse link
G HRG histidine rich glycoprotein involved_in ISO (PMID:16489009) UniProt PMID:16489009 NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537
JBrowse link
G PLXNB3 plexin B3 involved_in ISO PMID:20696765 UniProt PMID:20696765 RGD:8554409 NCBI chr  X:121,577,564...121,593,294
Ensembl chr  X:121,580,073...121,593,287
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in ISO (PMID:21107423) ARUK-UCL PMID:21107423 NCBI chr37:12,162,815...12,278,505
Ensembl chr37:12,162,392...12,282,395
JBrowse link
G ACTR2 actin related protein 2 involved_in ISO (PMID:29058690) UniProt PMID:29058690 NCBI chr10:64,696,068...64,733,027
Ensembl chr10:64,696,111...64,730,553
JBrowse link
G ACTR3 actin related protein 3 involved_in ISO (PMID:29058690) RGD
UniProt
PMID:18256280 PMID:29058690 RGD:2306202 NCBI chr19:35,097,968...35,133,330
Ensembl chr19:35,098,639...35,169,724
JBrowse link
G AKIRIN1 akirin 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr15:3,759,559...3,771,651
Ensembl chr15:3,763,374...3,771,551
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO RGD PMID:19539607 RGD:2316079 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 involved_in ISO (PMID:18560548) RGD
UniProt
PMID:15252126 PMID:18560548 RGD:2306210 NCBI chr37:24,914,389...24,935,998
Ensembl chr37:24,914,642...24,935,824
JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:20671235 RGD:11341707 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 involved_in ISO (MGI:5908783|PMID:25533347) UniProt PMID:25533347 MGI:5908783 NCBI chr 6:2,747,288...3,875,774
Ensembl chr 6:2,748,598...3,875,611
JBrowse link
G AVIL advillin involved_in ISO (PMID:29058690) UniProt PMID:29058690 NCBI chr10:1,855,598...1,875,156
Ensembl chr10:1,856,162...1,872,303
JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in ISO (PMID:18560548)
(PMID:21107423)
UniProt
ARUK-UCL
PMID:18560548 PMID:21107423 NCBI chr20:8,220,109...8,231,337
Ensembl chr20:8,221,575...8,231,258
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) UniProt PMID:26466680 NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:15252126 RGD:2306210 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212
JBrowse link
G CLRN1 clarin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:19423712) MGI
Ensembl
Ensembl
PMID:19423712 GO_REF:0000107 NCBI chr23:45,512,639...45,551,010
Ensembl chr23:45,513,416...45,551,178
JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) ARUK-UCL PMID:21107423 NCBI chr 3:32,096,471...32,170,107
Ensembl chr 3:32,097,037...32,187,781
JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:14617821 RGD:9685179 NCBI chr20:50,398,866...50,487,303
Ensembl chr20:50,398,864...50,487,241
JBrowse link
G FRMD7 FERM domain containing 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5546532|PMID:23967341) MGI
Ensembl
Ensembl
PMID:23967341 GO_REF:0000107 MGI:5546532 NCBI chr  X:103,027,980...103,055,139
Ensembl chr  X:103,028,814...103,079,148
JBrowse link
G FSCN1 fascin actin-bundling protein 1 involved_in ISO (PMID:9571235) UniProt PMID:9571235 NCBI chr 6:12,360,849...12,370,906
Ensembl chr 6:12,354,599...12,370,808
JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:24166750 RGD:9681442 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:15302889 RGD:2316937 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243
JBrowse link
G LOC403934 cell division cycle 42 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 2:77,153,276...77,169,947
Ensembl chr 2:77,153,095...77,199,211
JBrowse link
G MSTN myostatin involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr37:729,172...734,255
Ensembl chr37:729,172...734,362
JBrowse link
G MTOR mechanistic target of rapamycin kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3510095|PMID:15467718) MGI
Ensembl
Ensembl
PMID:15467718 GO_REF:0000107 MGI:3510095 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114
JBrowse link
G NCKAP1 NCK associated protein 1 involved_in ISO (PMID:21107423)
(MGI:5897521|PMID:27927633)
(PMID:18560548)
ARUK-UCL
BHF-UCL
UniProt
PMID:18560548 PMID:21107423 PMID:27927633 MGI:5897521 NCBI chr36:25,965,243...26,054,775
Ensembl chr36:25,965,938...26,054,760
JBrowse link
G OCLN occludin involved_in IMP (PMID:20152177) ARUK-UCL
ARUK-UCL
PMID:20152177 NCBI chr 2:54,500,299...54,545,430
Ensembl chr 2:54,500,299...54,545,430
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970
JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in ISO (PMID:29058690) UniProt PMID:29058690 NCBI chr28:8,209,707...8,484,427
Ensembl chr28:8,210,058...8,481,770
JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within
involved_in
ISO (PMID:15467718)
(PMID:19625648), (PMID:8625410)
RGD
MGI
UniProt
PMID:8625410 PMID:12105187 PMID:15467718 PMID:19625648 RGD:1299247 NCBI chr 6:11,726,259...11,758,532
Ensembl chr 6:11,655,494...11,757,216
JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:27,295,597...27,311,864
Ensembl chr10:27,295,640...27,311,397
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in ISO (PMID:17910947) BHF-UCL PMID:17910947 NCBI chr20:37,529,322...37,539,955
Ensembl chr20:37,529,401...37,539,957
JBrowse link
G WASF2 WASP family member 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:72,800,959...72,873,728
Ensembl chr 2:72,850,525...72,872,403
JBrowse link
G WNT1 Wnt family member 1 involved_in ISO (PMID:19756656) BHF-UCL PMID:19756656 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16237
    cellular process 15517
      regulation of cellular process 10657
        regulation of cellular component biogenesis 1033
          regulation of cell projection assembly 234
            regulation of plasma membrane bounded cell projection assembly 231
              regulation of lamellipodium assembly 43
                negative regulation of lamellipodium assembly 5
                positive regulation of lamellipodium assembly 31
Path 2
Term Annotations click to browse term
  biological_process 16237
    cellular process 15517
      cellular component organization or biogenesis 6108
        cellular component organization 5941
          cell projection organization 1726
            plasma membrane bounded cell projection organization 1698
              lamellipodium organization 96
                lamellipodium assembly 76
                  regulation of lamellipodium assembly 43
                    negative regulation of lamellipodium assembly 5
                    positive regulation of lamellipodium assembly 31
paths to the root