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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lamellipodium assembly
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Accession:GO:0010591 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:related_synonym: regulation of lamellipodium biogenesis



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regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN3 bridging integrator 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5517720|PMID:23872330) MGI
Ensembl
PMID:23872330 GO_REF:0000107 MGI:5517720 NCBI chr 8:21,870,784...21,919,077
Ensembl chr 8:18,809,582...18,858,912
JBrowse link
G CDC42 cell division cycle 42 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G DMTN dematin actin binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229
JBrowse link
G EPHA2 EPH receptor A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787
JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:104,099,620...104,548,077
Ensembl chr 5:109,964,823...110,350,576
JBrowse link
G RAC1 Rac family small GTPase 1 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G WAS WASP actin nucleation promoting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380
JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI3 ABI family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,381,551...8,394,537
Ensembl chr17:8,364,561...8,376,930
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:24093776 RGD:11570550 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806
JBrowse link
G HRG histidine rich glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:183,701,069...183,712,365
Ensembl chr 3:192,168,299...192,180,539
JBrowse link
G PLXNB3 plexin B3 involved_in ISO PMID:20696765 UniProt PMID:20696765 RGD:8554409 NCBI chr  X:143,314,794...143,330,066
Ensembl chr  X:153,200,971...153,215,909
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656
JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in ISO (PMID:21107423) ARUK-UCL PMID:21107423 NCBI chr2B:90,561,708...90,663,072
Ensembl chr2B:208,702,092...208,797,499
JBrowse link
G ACTR2 actin related protein 2 involved_in ISO (PMID:29058690) UniProt PMID:29058690 NCBI chr2A:65,289,675...65,333,219 JBrowse link
G ACTR3 actin related protein 3 involved_in ISO
IEA
RGD
Ensembl
PMID:18256280 GO_REF:0000107 RGD:2306202 NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729
JBrowse link
G AKIRIN1 akirin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:38,269,096...38,283,920
Ensembl chr 1:39,616,036...39,629,300
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO RGD PMID:19539607 RGD:2316079 NCBI chr 7:31,524,933...31,538,602
Ensembl chr 7:31,644,331...31,658,141
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 involved_in ISO
IEA
RGD
Ensembl
PMID:15252126 GO_REF:0000107 RGD:2306210 NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643
JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:20671235 RGD:11341707 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756
JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 involved_in ISO (MGI:5908783|PMID:25533347) UniProt PMID:25533347 MGI:5908783 NCBI chr 7:64,822,964...66,015,831
Ensembl chr 7:77,495,909...78,686,763
JBrowse link
G AVIL advillin involved_in ISO (PMID:29058690) UniProt PMID:29058690 NCBI chr12:31,108,569...31,129,307
Ensembl chr12:31,369,872...31,389,847
JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,051,054...10,062,364
Ensembl chr 3:10,403,896...10,415,545
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709
JBrowse link
G CDC42 cell division cycle 42 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:15252126 RGD:2306210 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806
JBrowse link
G CLRN1 clarin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:19423712) MGI
Ensembl
PMID:19423712 GO_REF:0000107 NCBI chr 3:147,954,124...148,000,895
Ensembl chr 3:155,526,011...155,573,684
JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:20,462,811...20,573,684 JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:14617821 RGD:9685179 NCBI chr19:10,272,172...10,386,032
Ensembl chr19:10,933,672...11,106,478
JBrowse link
G FRMD7 FERM domain containing 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5546532|PMID:23967341) MGI
Ensembl
PMID:23967341 GO_REF:0000107 MGI:5546532 NCBI chr  X:121,208,961...121,259,708
Ensembl chr  X:131,516,484...131,567,394
JBrowse link
G FSCN1 fascin actin-bundling protein 1 involved_in ISO (PMID:9571235) UniProt PMID:9571235 NCBI chr 7:5,848,902...5,862,756 JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:24166750 RGD:9681442 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:15302889 RGD:2316937 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G LOC100986336 twinfilin-2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
JBrowse link
G MSTN myostatin involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922
JBrowse link
G MTOR mechanistic target of rapamycin kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3510095|PMID:15467718) MGI
Ensembl
PMID:15467718 GO_REF:0000107 MGI:3510095 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G NCKAP1 NCK associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710
JBrowse link
G OCLN occludin involved_in ISO (PMID:20152177) ARUK-UCL PMID:20152177 NCBI chr 5:44,447,230...44,509,637
Ensembl chr 5:46,023,437...46,069,342
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:90,731,695...91,065,846
Ensembl chr10:94,278,550...94,575,024
JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within
involved_in
ISO (PMID:15467718)
(PMID:19625648), (PMID:8625410)
RGD
MGI
UniProt
PMID:8625410 PMID:12105187 PMID:15467718 PMID:19625648 RGD:1299247 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:18,138,517...18,159,023
Ensembl chr22:35,973,229...35,992,026
JBrowse link
G WASF2 WASP family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,665,853...26,750,618
Ensembl chr 1:27,717,538...27,737,316
JBrowse link
G WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15229
    cellular process 14344
      regulation of cellular process 9752
        regulation of cellular component biogenesis 999
          regulation of cell projection assembly 223
            regulation of plasma membrane bounded cell projection assembly 220
              regulation of lamellipodium assembly 40
                negative regulation of lamellipodium assembly 5
                positive regulation of lamellipodium assembly 31
Path 2
Term Annotations click to browse term
  biological_process 15229
    cellular process 14344
      cellular component organization or biogenesis 5571
        cellular component organization 5440
          cell projection organization 1590
            plasma membrane bounded cell projection organization 1567
              lamellipodium organization 93
                lamellipodium assembly 73
                  regulation of lamellipodium assembly 40
                    negative regulation of lamellipodium assembly 5
                    positive regulation of lamellipodium assembly 31
paths to the root