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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lamellipodium assembly
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Accession:GO:0010591 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:related_synonym: regulation of lamellipodium biogenesis



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regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin3 bridging integrator 3 acts_upstream_of_or_within ISO MGI:3512131 (MGI:5517720|PMID:23872330) RGD PMID:23872330 MGI:5517720 NCBI chr15:45,173,725...45,212,607
Ensembl chr15:45,173,732...45,212,604
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO UniProtKB:P42768 (PMID:8625410) RGD PMID:8625410 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Dmtn dematin actin binding protein involved_in ISO (PMID:10565303) RGD PMID:10565303 NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601
JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:19573808) RGD PMID:19573808 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Fer FER tyrosine kinase involved_in ISO
IEA
ISS
(PMID:19738202)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:19738202 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451
JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO UniProtKB:P42768 (PMID:8625410) RGD PMID:8625410 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894
JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298
JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO UniProtKB:P60953|UniProtKB:P63000 (PMID:8625410) RGD PMID:8625410 NCBI chr  X:14,405,096...14,413,850
Ensembl chr  X:14,405,124...14,413,849
JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family, member 3 involved_in ISO (MGI:6508508|PMID:26428302) RGD PMID:26428302 MGI:6508508 NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816
JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:24093776 RGD:11570550 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISO
ISS
IEA
(PMID:16489009)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:16489009 GO_REF:0000024 GO_REF:0000107 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in ISS
IEA
GO_REF:0000024
GO_REF:0000107
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Plxnb3 plexin B3 involved_in IMP PMID:20696765 UniProt PMID:20696765 RGD:8554409 NCBI chr  X:151,493,832...151,508,688
Ensembl chr  X:151,494,207...151,508,674
JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA
(PMID:16439689)
GO_REF:0000107
RGD
Ensembl
PMID:16439689 GO_REF:0000107 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Actr2 actin related protein 2 involved_in ISO (PMID:29058690) RGD PMID:29058690 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
JBrowse link
G Actr3 actin related protein 3 involved_in IMP
IEA
ISO
ISS
GO_REF:0000107
(PMID:29058690)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:29058690 PMID:18256280 GO_REF:0000024 GO_REF:0000107, RGD:2306202 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
JBrowse link
G Akirin1 akirin 1 involved_in IBA
ISO
PMID:21873635
(MGI:3850794|PMID:19406121)
RGD PMID:19406121 PMID:21873635 MGI:3850794, RGD:13792537 NCBI chr 5:135,989,378...136,004,782
Ensembl chr 5:135,989,465...136,004,762
JBrowse link
G Aqp1 aquaporin 1 IMP RGD PMID:19539607 RGD:2316079 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 involved_in IMP
IEA
ISO
GO_REF:0000107
(PMID:18560548)
Ensembl
RGD
PMID:18560548 PMID:15252126 GO_REF:0000107, RGD:2306210 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Atp7a ATPase copper transporting alpha IMP RGD PMID:20671235 RGD:11341707 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 involved_in ISO (MGI:5908783|PMID:25533347) RGD PMID:25533347 MGI:5908783
G Avil advillin involved_in ISO
ISS
(PMID:29058690)
GO_REF:0000024
RGD
UniProt
PMID:29058690 GO_REF:0000024 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in ISO (PMID:18560548), (PMID:21107423) RGD PMID:18560548 PMID:21107423 NCBI chr 4:146,750,821...146,766,050
Ensembl chr 4:146,750,821...146,768,856
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO (PMID:8625410) RGD PMID:8625410 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Clrn1 clarin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:19423712)
GO_REF:0000107
RGD
Ensembl
PMID:19423712 GO_REF:0000107 NCBI chr 2:143,084,030...143,130,948
Ensembl chr 2:143,084,030...143,130,948
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14617821 RGD:9685179 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Frmd7 FERM domain containing 7 acts_upstream_of_or_within ISO (MGI:5546532|PMID:23967341) RGD PMID:23967341 MGI:5546532 NCBI chr  X:130,375,925...130,423,836
Ensembl chr  X:130,377,227...130,423,771
JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:9571235)
UniProt
Ensembl
RGD
PMID:9571235 GO_REF:0000024 GO_REF:0000107 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IMP RGD PMID:15302889 RGD:2316937 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Mstn myostatin involved_in ISS
ISO
GO_REF:0000024
(MGI:3850794|PMID:19406121)
UniProt
RGD
PMID:19406121 GO_REF:0000024 MGI:3850794 NCBI chr 9:48,453,982...48,458,809
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:3510095|PMID:15467718) RGD PMID:15467718 MGI:3510095 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nckap1 NCK-associated protein 1 involved_in ISO
IEA
(PMID:18560548), (PMID:21107423)
GO_REF:0000107
(MGI:5897521|PMID:27927633)
RGD
Ensembl
PMID:18560548 PMID:21107423 PMID:27927633 GO_REF:0000107 MGI:5897521 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217
JBrowse link
G Ocln occludin involved_in ISO (PMID:20152177) RGD PMID:20152177 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:6450670|PMID:11038173)
Ensembl
RGD
PMID:11038173 GO_REF:0000107 MGI:6450670 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:29058690)
UniProt
Ensembl
RGD
PMID:29058690 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
JBrowse link
G Rac1 Rac family small GTPase 1 involved_in
acts_upstream_of_or_within
IMP
IEA
ISO
GO_REF:0000107
(PMID:15467718)
(PMID:19625648), (PMID:8625410)
Ensembl
RGD
PMID:8625410 PMID:15467718 PMID:19625648 PMID:12105187 GO_REF:0000107, RGD:1299247 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO (PMID:19625648)
(MGI:4355276|PMID:19625648)
RGD PMID:19625648 MGI:4355276 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in ISO (PMID:17910947) RGD PMID:17910947 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298
JBrowse link
G Wasf2 WASP family member 2 involved_in ISO (PMID:18560548), (PMID:21107423) RGD PMID:18560548 PMID:21107423 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:19756656) RGD PMID:19756656 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    cellular process 18637
      regulation of cellular process 12501
        regulation of cellular component biogenesis 1074
          regulation of cell projection assembly 239
            regulation of plasma membrane bounded cell projection assembly 236
              regulation of lamellipodium assembly 43
                negative regulation of lamellipodium assembly 6
                positive regulation of lamellipodium assembly 31
Path 2
Term Annotations click to browse term
  biological_process 19834
    cellular process 18637
      cellular component organization or biogenesis 6736
        cellular component organization 6486
          cell projection organization 1774
            plasma membrane bounded cell projection organization 1734
              lamellipodium organization 97
                lamellipodium assembly 77
                  regulation of lamellipodium assembly 43
                    negative regulation of lamellipodium assembly 6
                    positive regulation of lamellipodium assembly 31
paths to the root