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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lamellipodium assembly
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Accession:GO:0010591 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:related_synonym: regulation of lamellipodium biogenesis
 never_in_taxon: NCBITaxon:4890 ! Ascomycota


show annotations for term's descendants           Sort by:
regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin3 bridging integrator 3 acts_upstream_of_or_within ISO MGI:3512131 (PMID:23872330) RGD PMID:23872330 NCBI chr15:51,583,474...51,622,329
Ensembl chr15:45,173,732...45,212,604 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:151,434,871...151,535,409 		JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO UniProtKB:P42768 (PMID:8625410) RGD PMID:8625410 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Dmtn dematin actin binding protein involved_in ISO
IEA		 (PMID:10565303)
GO_REF:0000107		 RGD
Ensembl		 PMID:10565303 GO_REF:0000107 NCBI chr15:52,087,667...52,111,956
Ensembl chr15:45,677,977...45,705,601 		JBrowse link
G ENSRNOG00000066279 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:36,411,605...36,413,032 JBrowse link
G Epha2 Eph receptor A2 involved_in ISO
IEA		 (PMID:19573808)
GO_REF:0000107		 RGD
Ensembl		 PMID:19573808 GO_REF:0000107 NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Fer FER tyrosine kinase involved_in ISO
IEA
ISS		 (PMID:19738202)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19738202 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO UniProtKB:P42768 (PMID:8625410) RGD PMID:8625410 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:127,595,210...127,607,821
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:115,723,980...115,737,025
Ensembl chr 8:106,845,253...106,858,298 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO
IEA		 UniProtKB:P60953|UniProtKB:P63000 (PMID:8625410)
GO_REF:0000107		 RGD
Ensembl		 PMID:8625410 GO_REF:0000107 NCBI chr  X:17,077,057...17,085,802
Ensembl chr  X:14,405,124...14,413,849 		JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family, member 3 involved_in ISO
IEA		 (PMID:26428302)
GO_REF:0000107		 RGD
Ensembl		 PMID:26428302 GO_REF:0000107 NCBI chr10:81,266,571...81,277,561
Ensembl chr10:80,769,822...80,780,816 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:24093776 RGD:11570550 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISO
ISS		 (PMID:16489009)
GO_REF:0000024		 RGD
UniProt		 PMID:16489009 GO_REF:0000024 NCBI chr11:91,559,087...91,573,982
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:91,543,964...91,553,946
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Mir196a1 microRNA 196a-1 involved_in ISO (PMID:22773844) RGD PMID:22773844 NCBI chr10:81,231,006...81,231,085
Ensembl chr10:81,231,006...81,231,085 		JBrowse link
G Mir196a2 microRNA 196a-2 involved_in ISO (PMID:22773844) RGD PMID:22773844 NCBI chr 7:135,988,876...135,988,985
Ensembl chr 7:134,110,400...134,110,509 		JBrowse link
G Plxnb3 plexin B3 involved_in IMP PMID:20696765 UniProt PMID:20696765 RGD:8554409 NCBI chr  X:156,645,505...156,660,011
Ensembl chr  X:151,494,207...151,508,674 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA		 (PMID:16439689)
GO_REF:0000107		 RGD
Ensembl		 PMID:16439689 GO_REF:0000107 NCBI chr14:66,829,661...67,168,517
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Actr2 actin related protein 2 involved_in ISO
IEA		 (PMID:29058690)
GO_REF:0000107		 RGD
Ensembl		 PMID:29058690 GO_REF:0000107 NCBI chr14:98,500,119...98,535,092
Ensembl chr14:94,296,443...94,340,524 		JBrowse link
G Actr3 actin related protein 3 involved_in IMP
ISO
ISS		 (PMID:29058690)
GO_REF:0000024		 RGD
UniProt		 PMID:29058690 PMID:18256280 GO_REF:0000024, RGD:2306202 NCBI chr13:39,353,413...39,396,509
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Akirin1 akirin 1 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:19406121)		 GO_Central
Ensembl
RGD		 PMID:19406121 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:141,274,174...141,289,617
Ensembl chr 5:135,989,465...136,004,762 		JBrowse link
G Aqp1 aquaporin 1 IMP RGD PMID:19539607 RGD:2316079 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:18560548)		 Ensembl
RGD		 PMID:18560548 PMID:15252126 GO_REF:0000107, RGD:2306210 NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Atp7a ATPase copper transporting alpha IMP RGD PMID:20671235 RGD:11341707 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 involved_in ISO (PMID:25533347) RGD PMID:25533347 NCBI chr12:29,739,138...30,830,386
Ensembl chr12:24,104,192...25,194,416 		JBrowse link
G Avil advillin involved_in ISO
IEA
ISS		 (PMID:29058690)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29058690 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in ISO
IEA		 (PMID:18560548), (PMID:21107423)
GO_REF:0000107		 RGD
Ensembl		 PMID:18560548 PMID:21107423 GO_REF:0000107 NCBI chr 4:148,306,436...148,321,668
Ensembl chr 4:146,750,821...146,768,856 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO
IEA		 (PMID:26466680)
GO_REF:0000107		 RGD
Ensembl		 PMID:26466680 GO_REF:0000107 NCBI chr19:50,481,911...50,496,672
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO (PMID:8625410) RGD PMID:8625410 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Clrn1 clarin 1 acts_upstream_of_or_within ISO
IEA		 (PMID:19423712)
GO_REF:0000107		 RGD
Ensembl		 PMID:19423712 GO_REF:0000107 NCBI chr 2:145,233,941...145,280,855
Ensembl chr 2:143,084,030...143,130,948 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14617821 RGD:9685179 NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Frmd7 FERM domain containing 7 acts_upstream_of_or_within ISO
IEA		 (PMID:23967341)
GO_REF:0000107		 RGD
Ensembl		 PMID:23967341 GO_REF:0000107 NCBI chr  X:130,375,925...130,423,836
Ensembl chr  X:130,377,227...130,423,771 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:9571235)		 UniProt
Ensembl
RGD		 PMID:9571235 GO_REF:0000024 GO_REF:0000107 NCBI chr12:16,710,601...16,723,734
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IMP RGD PMID:15302889 RGD:2316937 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Mstn myostatin involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19406121)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19406121 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:55,944,513...55,950,913
Ensembl chr 9:48,452,533...48,458,933 		JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO
IEA		 (PMID:15467718)
GO_REF:0000107		 RGD
Ensembl		 PMID:15467718 GO_REF:0000107 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nckap1 NCK-associated protein 1 involved_in ISO
IEA		 (PMID:18560548), (PMID:21107423)
GO_REF:0000107
(PMID:27927633)		 RGD
Ensembl		 PMID:18560548 PMID:21107423 PMID:27927633 GO_REF:0000107 NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Ocln occludin involved_in ISO (PMID:20152177) RGD PMID:20152177 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:11038173) RGD PMID:11038173 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29058690)		 UniProt
Ensembl
RGD		 PMID:29058690 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:236,244,683...236,551,438 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in
acts_upstream_of_or_within		 IMP
IBA
ISO		 GO_REF:0000033
(PMID:15467718)
(PMID:19625648), (PMID:8625410)		 GO_Central
RGD		 PMID:8625410 PMID:15467718 PMID:19625648 PMID:12105187 GO_REF:0000033, RGD:1299247 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO
IEA
IBA		 (PMID:19625648)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19625648 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in ISO
IEA		 (PMID:17910947)
GO_REF:0000107		 RGD
Ensembl		 PMID:17910947 GO_REF:0000107 NCBI chr 8:115,723,980...115,737,025
Ensembl chr 8:106,845,253...106,858,298 		JBrowse link
G Wasf2 WASP family member 2 involved_in ISO
IEA		 (PMID:18560548), (PMID:21107423)
GO_REF:0000107		 RGD
Ensembl		 PMID:18560548 PMID:21107423 GO_REF:0000107 NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO
IEA		 (PMID:19756656)
GO_REF:0000107		 RGD
Ensembl		 PMID:19756656 GO_REF:0000107 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      regulation of cellular process 13038
        regulation of cellular component biogenesis 1154
          regulation of cell projection assembly 248
            regulation of plasma membrane bounded cell projection assembly 245
              regulation of lamellipodium assembly 46
                negative regulation of lamellipodium assembly 8
                positive regulation of lamellipodium assembly 31
Path 2
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      cellular component organization or biogenesis 7115
        cellular component organization 6828
          cell projection organization 1889
            plasma membrane bounded cell projection organization 1849
              lamellipodium organization 101
                lamellipodium assembly 80
                  regulation of lamellipodium assembly 46
                    negative regulation of lamellipodium assembly 8
                    positive regulation of lamellipodium assembly 31
paths to the root