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ONTOLOGY REPORT - ANNOTATIONS


Term:miRNA catabolic process
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Accession:GO:0010587 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
Synonyms:exact_synonym: microRNA catabolic process


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miRNA catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dis3l2 DIS3 like 3'-5' exoribonuclease 2 ISO (PMID:24141620)
(MGI:MGI:5494337|PMID:23594738)
(MGI:MGI:5603455|PMID:25119025)
UniProtKB PMID:23594738, PMID:24141620, PMID:25119025 MGI:MGI:5494337, MGI:MGI:5603455 NCBI chrNW_004936525:4,718,773...5,058,512 JBrowse link
G Lin28a lin-28 homolog A ISO (PMID:18951094), (PMID:19703396)
(MGI:MGI:4359358|PMID:18604195), (MGI:MGI:4359360|PMID:18292307)
UniProtKB PMID:18292307, PMID:18604195, PMID:18951094, PMID:19703396 MGI:MGI:4359358, MGI:MGI:4359360 NCBI chrNW_004936474:10,896,153...10,909,247 JBrowse link
G Lin28b lin-28 homolog B ISO (PMID:19703396) UniProtKB PMID:19703396 NCBI chrNW_004936564:1,646,469...1,768,879 JBrowse link
G Parn poly(A)-specific ribonuclease ISO (PMID:25049417) UniProtKB PMID:25049417 NCBI chrNW_004936501:2,666,908...2,810,159 JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 ISO (PMID:28546213) UniProtKB PMID:28546213 NCBI chrNW_004936479:14,848,438...15,259,735 JBrowse link
G Tent4b terminal nucleotidyltransferase 4B ISO (PMID:25049417) UniProtKB PMID:25049417 NCBI chrNW_004936475:3,266,763...3,328,209 JBrowse link
G Tut4 terminal uridylyl transferase 4 ISO (PMID:19703396) UniProtKB PMID:19703396 NCBI chrNW_004936522:8,468,092...8,560,453 JBrowse link
negative regulation of miRNA catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tent2 terminal nucleotidyltransferase 2 ISO (PMID:23200856) UniProtKB PMID:23200856 NCBI chrNW_004936549:7,401,532...7,465,264 JBrowse link
positive regulation of miRNA catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lin28b lin-28 homolog B ISO (PMID:18951094) CACAO PMID:18951094 NCBI chrNW_004936564:1,646,469...1,768,879 JBrowse link
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 ISO (PMID:20547861) UniProtKB PMID:20547861 NCBI chrNW_004936491:1,989,429...2,032,430 JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A ISO (PMID:22055188), (PMID:24048733) UniProtKB PMID:22055188, PMID:24048733 NCBI chrNW_004936474:19,714,145...19,722,512 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      primary metabolic process 6774
        nucleobase-containing compound metabolic process 3574
          nucleobase-containing compound catabolic process 266
            RNA catabolic process 191
              ncRNA catabolic process 24
                miRNA catabolic process 10
                  negative regulation of miRNA catabolic process 1
                  positive regulation of miRNA catabolic process 3
                  regulation of miRNA catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      cellular metabolic process 7051
        cellular aromatic compound metabolic process 3743
          nucleobase-containing compound metabolic process 3574
            nucleic acid metabolic process 3288
              RNA metabolic process 2915
                ncRNA metabolic process 250
                  miRNA metabolic process 25
                    miRNA catabolic process 10
                      negative regulation of miRNA catabolic process 1
                      positive regulation of miRNA catabolic process 3
                      regulation of miRNA catabolic process + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.