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ONTOLOGY REPORT - ANNOTATIONS


Term:miRNA catabolic process
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Accession:GO:0010587 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
Synonyms:exact_synonym: microRNA catabolic process


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miRNA catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DIS3L2 DIS3 like 3'-5' exoribonuclease 2 ISO (MGI:MGI:5603455|PMID:25119025)
(PMID:24141620)
(MGI:MGI:5494337|PMID:23594738)
UniProtKB PMID:23594738, PMID:24141620, PMID:25119025 MGI:MGI:5494337, MGI:MGI:5603455 NCBI chr2B:119,187,659...119,558,347
Ensembl chr2B:238,030,931...238,347,570
JBrowse link
G LIN28A lin-28 homolog A ISO (PMID:18951094), (PMID:19703396)
(MGI:MGI:4359358|PMID:18604195), (MGI:MGI:4359360|PMID:18292307)
UniProtKB PMID:18292307, PMID:18604195, PMID:18951094, PMID:19703396 MGI:MGI:4359358, MGI:MGI:4359360 NCBI chr 1:25,674,751...25,693,684
Ensembl chr 1:26,739,268...26,758,028
JBrowse link
G LIN28B lin-28 homolog B ISO (PMID:19703396) UniProtKB PMID:19703396 NCBI chr 6:102,755,256...102,897,739
Ensembl chr 6:106,640,448...106,772,374
JBrowse link
G PARN poly(A)-specific ribonuclease ISO (PMID:25049417) UniProtKB PMID:25049417 NCBI chr16:13,363,879...13,556,054
Ensembl chr16:14,787,881...14,977,786
JBrowse link
G SND1 staphylococcal nuclease and tudor domain containing 1 ISO (PMID:28546213) UniProtKB PMID:28546213 NCBI chr 7:119,647,536...120,084,110
Ensembl chr 7:132,302,235...132,738,223
JBrowse link
G TENT4B terminal nucleotidyltransferase 4B ISO (PMID:25049417) UniProtKB PMID:25049417 NCBI chr16:30,415,668...30,494,758
Ensembl chr16:49,299,498...49,373,665
JBrowse link
G TUT4 terminal uridylyl transferase 4 ISO (PMID:19703396) UniProtKB PMID:19703396 NCBI chr 1:51,684,408...51,815,059
Ensembl chr 1:53,292,477...53,422,893
JBrowse link
negative regulation of miRNA catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TENT2 terminal nucleotidyltransferase 2 ISO (PMID:23200856) UniProtKB PMID:23200856 NCBI chr 5:35,622,645...35,696,451
Ensembl chr 5:35,893,841...35,966,932
JBrowse link
positive regulation of miRNA catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIN28B lin-28 homolog B ISO (PMID:18951094) CACAO PMID:18951094 NCBI chr 6:102,755,256...102,897,739
Ensembl chr 6:106,640,448...106,772,374
JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 ISO (PMID:20547861) UniProtKB PMID:20547861 NCBI chr2A:55,792,412...55,848,242
Ensembl chr2A:56,931,365...56,986,326
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A ISO (PMID:22055188), (PMID:24048733) UniProtKB PMID:22055188, PMID:24048733 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12524
    metabolic process 7962
      primary metabolic process 7030
        nucleobase-containing compound metabolic process 3691
          nucleobase-containing compound catabolic process 280
            RNA catabolic process 199
              ncRNA catabolic process 27
                miRNA catabolic process 10
                  negative regulation of miRNA catabolic process 1
                  positive regulation of miRNA catabolic process 3
                  regulation of miRNA catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 12524
    metabolic process 7962
      cellular metabolic process 7310
        cellular aromatic compound metabolic process 3867
          nucleobase-containing compound metabolic process 3691
            nucleic acid metabolic process 3388
              RNA metabolic process 3006
                ncRNA metabolic process 256
                  miRNA metabolic process 26
                    miRNA catabolic process 10
                      negative regulation of miRNA catabolic process 1
                      positive regulation of miRNA catabolic process 3
                      regulation of miRNA catabolic process + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.