positive regulation of phosphorus metabolic process - Ontology Report

RGD

PMID:9314843

RGD:6478796

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

Ghr

growth hormone receptor

RGD

PMID:11244571

RGD:1624962

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

Il3

interleukin 3

acts_upstream_of_or_within

(MGI:63384|PMID:8378315)

PMID:8378315

MGI:63384

NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066

Il4

interleukin 4

involved_in

UniProtKB:P08575 (PMID:12574355)
PMID:21873635

PMID:12574355 PMID:21873635

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Jak2

Janus kinase 2

involved_in

GO_REF:0000024
(MGI:4457458|PMID:20304997)

PMID:20304997

GO_REF:0000024 MGI:4457458

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Pibf1

progesterone immunomodulatory binding factor 1

involved_in

(PMID:16393965)

PMID:16393965

NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712

Prl3d4

prolactin family 3, subfamily D, member 4

RGD

PMID:8822264

RGD:1298822

NCBI chr17:37,325,804...37,332,641
Ensembl chr17:37,325,806...37,332,667

Prlr

prolactin receptor

involved_in

GO_REF:0000107
(PMID:10585417)

PMID:10585417

GO_REF:0000107

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

Ptk2b

protein tyrosine kinase 2 beta

involved_in

IMP
ISO

(PMID:8670418)

PMID:8670418 PMID:11818507

RGD:633057

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

activation of NF-kappaB-inducing kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Agt

angiotensinogen

acts_upstream_of_or_within

(MGI:3844151|PMID:19404405)

PMID:19404405

MGI:3844151

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

Card10

caspase recruitment domain family, member 10

involved_in

(PMID:11259443)

PMID:11259443

NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224

Chi3l1

chitinase 3 like 1

involved_in

GO_REF:0000024
(MGI:5306542|PMID:21546314)

PMID:21546314

GO_REF:0000024 MGI:5306542

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

Cops8

COP9 signalosome subunit 8

involved_in

(PMID:22992343)

PMID:22992343

NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258

Ikbkg

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

acts_upstream_of_or_within

(MGI:2682548|PMID:14654787)

PMID:14654787

MGI:2682548

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Irak1

interleukin-1 receptor-associated kinase 1

involved_in

(PMID:11397809)

PMID:11397809

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Irak2

interleukin-1 receptor-associated kinase 2

NOT|acts_upstream_of_or_within

(MGI:2388552|PMID:12220507)

PMID:12220507

MGI:2388552

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

Malt1

MALT1 paracaspase

involved_in

(PMID:15125833)

PMID:15125833

NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260

Map3k7

mitogen activated protein kinase kinase kinase 7

involved_in

(PMID:10094049), (PMID:15125833)

PMID:10094049 PMID:15125833

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

Mas1

MAS1 proto-oncogene, G protein-coupled receptor

acts_upstream_of_or_within

MGI:2158808 (MGI:3844151|PMID:19404405)

PMID:19404405

MGI:3844151

NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709

Tirap

TIR domain containing adaptor protein

involved_in

(PMID:24275656)

PMID:24275656

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Tnfsf15

TNF superfamily member 15

acts_upstream_of_or_within
involved_in

(PMID:11911831)
GO_REF:0000107

PMID:11911831

GO_REF:0000107

NCBI chr 5:77,140,099...77,156,142
Ensembl chr 5:77,139,878...77,156,228

Traf2

Tnf receptor-associated factor 2

involved_in

(PMID:15125833)

PMID:15125833

NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538

Traf4

Tnf receptor associated factor 4

involved_in

IEA

GO_REF:0000002

InterPro

GO_REF:0000002

NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284

Traf6

TNF receptor associated factor 6

involved_in

(PMID:15125833)

PMID:15125833

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

Zfp91

zinc finger protein 91

involved_in

(PMID:20682767)

PMID:20682767

NCBI chr 1:209,891,344...209,928,890
Ensembl chr 1:209,891,344...209,927,762

activation of protein kinase A activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcy8

adenylate cyclase 8

involved_in

PMID:25381556

UniProt

PMID:25381556

RGD:13825194

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

Fbn1

fibrillin 1

involved_in

(PMID:27087445)

PMID:27087445

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

Prrc1

proline-rich coiled-coil 1

involved_in

PMID:21873635

GO_Central

NCBI chr18:50,812,548...50,846,273
Ensembl chr18:50,812,552...50,849,476

urocortin

RGD

NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950

activation of protein kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adnp

activity-dependent neuroprotector homeobox

Fyn kinase

RGD

PMID:19047645

RGD:2312772

NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312

adrenoceptor alpha 2A

involved_in

(PMID:15653687)

PMID:15653687

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

axin 1

involved_in

(PMID:9601641)

PMID:9601641

NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615

Bora

bora, aurora kinase A activator

involved_in

PMID:21873635

GO_Central

NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322

Cab39

calcium binding protein 39

acts_upstream_of_or_within
involved_in

(MGI:3836081|PMID:18854309)
(PMID:19892943)

PMID:18854309 PMID:19892943

MGI:3836081

NCBI chr 9:86,463,008...86,524,545
Ensembl chr 9:86,463,095...86,524,544

Calca

calcitonin-related polypeptide alpha

involved_in

(PMID:17983652)

PMID:17983652

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

Camkk1

calcium/calmodulin-dependent protein kinase kinase 1

PMID:16054095 PMID:21873635

RGD

PMID:16054095

RGD:2311420

NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498

Camkk2

calcium/calmodulin-dependent protein kinase kinase 2

involved_in

IDA
IBA

PMID:21873635

RGD
GO_Central

RGD:2311420, RGD:13792537

NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279

Ccdc88a

coiled coil domain containing 88A

involved_in

(PMID:21954290)

PMID:21954290

NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368

Clspn

claspin

involved_in

PMID:21873635
(PMID:16885022)

PMID:16885022 PMID:21873635

NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034

Dlg1

discs large MAGUK scaffold protein 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:3697750|PMID:17187070)

PMID:17187070

GO_REF:0000107 MGI:3697750

NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689

dopamine receptor D2

RGD

NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875

Ect2

epithelial cell transforming 2

involved_in

(PMID:15254234)

PMID:15254234

NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911

Emp2

epithelial membrane protein 2

involved_in

(PMID:21637765)
GO_REF:0000024

PMID:21637765

GO_REF:0000024

NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733

HNF1 homeobox A

RGD

NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104

insulin receptor

involved_in

(PMID:9819385)

PMID:9819385

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

Itgb3

integrin subunit beta 3

involved_in

(PMID:10022831)
GO_REF:0000107

PMID:10022831

GO_REF:0000107

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

Kif14

kinesin family member 14

involved_in

(PMID:24784001)

PMID:24784001

NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164

platelet derived growth factor subunit B

involved_in

GO_REF:0000024
(PMID:16530387)

GO_REF:0000024

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

Ppp2r3c

protein phosphatase 2, regulatory subunit B'', gamma

acts_upstream_of_or_within

MGI:3759678 (MGI:3589325|PMID:16129705)

PMID:16129705

MGI:3589325

NCBI chr 6:72,647,025...72,670,885
Ensembl chr 6:72,647,025...72,672,491

Prkcd

protein kinase C, delta

involved_in

(PMID:10713049)

PMID:10713049

NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352

Prnp

prion protein

involved_in

ComplexPortal:CPX-1134 (MGI:5882868|PMID:23386614)

PMID:23386614

MGI:5882868

NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937

Ripk3

receptor-interacting serine-threonine kinase 3

involved_in

(PMID:22817896)
GO_REF:0000024

PMID:22817896

GO_REF:0000024

NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121

Sesn2

sestrin 2

acts_upstream_of_or_within

(MGI:6392416|PMID:31915252)

PMID:31915252

MGI:6392416

NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260

Slc11a1

solute carrier family 11 member 1

acts_upstream_of_or_within

MGI:1857755 (MGI:64652|PMID:8301134)

PMID:8301134

MGI:64652

NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101

Stk11

serine/threonine kinase 11

involved_in
acts_upstream_of_or_within

PMID:15731909
(PMID:18854309)
(PMID:15731909), (PMID:19892943)
(MGI:3836081|PMID:18854309)

PMID:15731909 PMID:18854309 PMID:19892943 PMID:15731909

MGI:3836081, RGD:13702324

NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315

Strada

STE20 related adaptor alpha

involved_in
acts_upstream_of_or_within

IDA
IBA
ISO

PMID:14511394
PMID:21873635
(PMID:12805220), (PMID:19892943)
(MGI:3836081|PMID:18854309)

PMID:12805220 PMID:18854309 PMID:19892943 PMID:14511394 PMID:21873635

MGI:3836081, RGD:1600691, RGD:13792537

NCBI chr10:91,094,849...91,123,890
Ensembl chr10:91,094,687...91,123,830

Stradb

STE20 related adaptor beta

involved_in

(PMID:14517248)
PMID:21873635

PMID:14517248 PMID:21873635

NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084

Tgfb2

transforming growth factor, beta 2

involved_in

(PMID:17192487), (PMID:17960115)
GO_REF:0000024

PMID:17192487 PMID:17960115

GO_REF:0000024

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

Tom1l1

target of myb1 like 1 membrane trafficking protein

involved_in

(PMID:16479011)

PMID:16479011

NCBI chr10:75,464,577...75,508,304
Ensembl chr10:75,464,577...75,508,250

Tpx2

TPX2, microtubule nucleation factor

involved_in

(PMID:14580337), (PMID:19801554)

PMID:14580337 PMID:19801554

NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468

Traf6

TNF receptor associated factor 6

involved_in

(PMID:17135271)

PMID:17135271

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

vascular endothelial growth factor A

involved_in

(PMID:18059339), (PMID:20497126)
GO_REF:0000107

PMID:18059339 PMID:20497126

GO_REF:0000107

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

Wnk4

WNK lysine deficient protein kinase 4

involved_in

(MGI:5892167|PMID:28096417)

PMID:28096417

MGI:5892167

NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829

activation of protein kinase B activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adrenoceptor alpha 2A

involved_in

(PMID:17215105)

PMID:17215105

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

Adra2b

adrenoceptor alpha 2B

involved_in

(PMID:17215105)

PMID:17215105

NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355

Adra2c

adrenoceptor alpha 2C

involved_in

(PMID:17215105)

PMID:17215105

NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846

Ang

angiogenin

involved_in

(PMID:17125737)

PMID:17125737

NCBI chr15:24,317,733...24,323,361

Ccdc88a

coiled coil domain containing 88A

involved_in

(MGI:3581096|PMID:15753085)

PMID:15753085

MGI:3581096

NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368

Dynap

dynactin associated protein

involved_in

(PMID:20978158)

PMID:20978158

NCBI chr18:63,885,164...63,909,464
Ensembl chr18:63,886,448...63,913,232

Dynapl1

dynactin associated protein-like 1

involved_in

PMID:21873635

GO_Central

NCBI chr18:63,865,136...63,868,338
Ensembl chr18:63,865,133...63,868,338

Fgf1

fibroblast growth factor 1

involved_in

GO_REF:0000024
(PMID:18441324)

PMID:18441324

GO_REF:0000024

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

Gas6

growth arrest specific 6

involved_in

PMID:18374201

UniProt

PMID:18374201

RGD:8554638

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

Igf1

insulin-like growth factor 1

involved_in

(PMID:22351760)
GO_REF:0000107

PMID:22351760

GO_REF:0000107

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

Il18

interleukin 18

involved_in

(PMID:21321938)
GO_REF:0000107

PMID:21321938

GO_REF:0000107

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Ins2

insulin 2

involved_in

(PMID:8702995)

PMID:8702995

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

insulin receptor

involved_in

(PMID:7556070)

PMID:7556070

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

Itgb1bp1

integrin subunit beta 1 binding protein 1

involved_in

(PMID:20616313)

PMID:20616313

NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037

Mir21

microRNA 21

involved_in

(PMID:22879939)

PMID:22879939

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

Mt3

metallothionein 3

involved_in

(PMID:18295594)
GO_REF:0000024

PMID:18295594

GO_REF:0000024

NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158

Notch2

notch receptor 2

acts_upstream_of_or_within
involved_in

(MGI:6876976|PMID:34635817)
GO_REF:0000107

PMID:34635817

GO_REF:0000107 MGI:6876976

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

Nrg1

neuregulin 1

involved_in

ISO
IEA
ISS

(PMID:20682778)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:20682778

GO_REF:0000024 GO_REF:0000107

NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884

Ntf3

neurotrophin 3

involved_in
acts_upstream_of

GO_REF:0000107
(PMID:23027130)

GO_REF:0000107

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

neurotrophic receptor tyrosine kinase 3

acts_upstream_of

(PMID:23027130)

NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286

Osbpl8

oxysterol binding protein-like 8

involved_in

(MGI:5644010|PMID:23812417)

PMID:23812417

MGI:5644010

NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888

platelet derived growth factor subunit B

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:16530387)

Ensembl
UniProt
RGD

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

Pdpk1

3-phosphoinositide dependent protein kinase-1

involved_in

(PMID:9368760)

PMID:9368760

NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623

Ppia

peptidylprolyl isomerase A

involved_in

GO_REF:0000024
(PMID:23180369)

PMID:23180369

GO_REF:0000024

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

Ppial4d

peptidylprolyl isomerase A (cyclophilin A)-like 4D

involved_in

ISS

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310

Prkcz

protein kinase C, zeta

in hepatocytes

RGD

PMID:15007074

RGD:1642700

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Slc1a1

solute carrier family 1 member 1

involved_in

(MGI:6478088|PMID:23827345)

PMID:23827345

MGI:6478088

NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in

PMID:16530387

UniProt

RGD:8553998

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

Tcl1a

Tcl1 family Akt coactivator A

involved_in

(MGI:6377804|PMID:28262547)

PMID:28262547

MGI:6377804

NCBI chr 6:124,125,032...124,131,025
Ensembl chr 6:124,125,032...124,131,025

Wnt family member 5A

acts_upstream_of

(PMID:20034610)

PMID:20034610

NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234

activation of protein kinase C activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abl1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

(PMID:10713049)

PMID:10713049

NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065

Cd86

CD86 molecule

involved_in

(MGI:5461234|PMID:23241883)

PMID:23241883

MGI:5461234

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

Lep

leptin

involved_in

IBA
ISO
ISS

PMID:21873635
(PMID:24340098)
GO_REF:0000024

PMID:24340098 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

Phb1

prohibitin 1

involved_in

GO_REF:0000024
(MGI:5461234|PMID:23241883)

PMID:23241883

GO_REF:0000024 MGI:5461234

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

Phb2

prohibitin 2

involved_in

ISO
ISS
IEA

(MGI:5461234|PMID:23241883)
GO_REF:0000024
GO_REF:0000107

RGD
UniProt
Ensembl

PMID:23241883

GO_REF:0000024 GO_REF:0000107 MGI:5461234

NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272

activation of transmembrane receptor protein tyrosine kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Angpt1

angiopoietin 1

involved_in

GO_REF:0000107
(PMID:19424712)

PMID:19424712

GO_REF:0000107

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

Chrna3

cholinergic receptor nicotinic alpha 3 subunit

acts_upstream_of_or_within

MGI:2155602 (MGI:3590443|PMID:16162937)

PMID:16162937

MGI:3590443

NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165

Nrg1

neuregulin 1

involved_in

(PMID:9553078)
PMID:21873635

PMID:9553078 PMID:21873635

NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884

Pdgfc

platelet derived growth factor C

acts_upstream_of_or_within

(MGI:1858279|PMID:10806482)

PMID:10806482

MGI:1858279

NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433

Prlr

prolactin receptor

involved_in

(PMID:10585417)
GO_REF:0000107

PMID:10585417

GO_REF:0000107

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

negative regulation of activation of Janus kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd300a

Cd300a molecule

involved_in

(PMID:16254138)

PMID:16254138

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

Hnf4a

hepatocyte nuclear factor 4, alpha

RGD

PMID:16584384

RGD:1625011

NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320

positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dgkz

diacylglycerol kinase zeta

involved_in

GO_REF:0000024
(MGI:6201900|PMID:27739494)
(PMID:15157668)

PMID:15157668 PMID:27739494

GO_REF:0000024 MGI:6201900

NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099

positive regulation of activation of Janus kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Agt

angiotensinogen

involved_in

(PMID:15153556)

PMID:15153556

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

Gh1

growth hormone 1

involved_in

(PMID:12552091)

PMID:12552091

NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078

Il12b

interleukin 12B

involved_in

(PMID:12023369)

PMID:12023369

NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903

Il23a

interleukin 23 subunit alpha

involved_in

(PMID:12023369)
PMID:21873635

PMID:12023369 PMID:21873635

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

Il6r

interleukin 6 receptor

involved_in

PMID:21873635
(PMID:12419823)

PMID:12419823 PMID:21873635

NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536

positive regulation of alkaline phosphatase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gpld1

glycosylphosphatidylinositol specific phospholipase D1

involved_in

ISS

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939

Itga2

integrin subunit alpha 2

RGD

PMID:10867645

RGD:2307406

NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481

Mef2c

myocyte enhancer factor 2C

involved_in

GO_REF:0000024
(MGI:5285459|PMID:21652706)

PMID:21652706

GO_REF:0000024 MGI:5285459

NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880

Npnt

nephronectin

involved_in

(MGI:4414689|PMID:19944102)

PMID:19944102

MGI:4414689

NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401

Ppargc1b

PPARG coactivator 1 beta

involved_in

(MGI:3838421|PMID:19252502)

PMID:19252502

MGI:3838421

NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194

Smad3

SMAD family member 3

rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity

RGD

PMID:12096832

RGD:727387

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

positive regulation of ATP biosynthetic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenylate cyclase 10

RGD

NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951

Bcl2l1

Bcl2-like 1

involved_in

PMID:23792689

CAFA

PMID:23792689

RGD:12793033

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

Eno1

enolase 1

involved_in

UniProtKB:Q01986 (PMID:15459207)

PMID:15459207

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

HNF1 homeobox A

RGD

NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104

Il4

interleukin 4

involved_in

(MGI:6304699|PMID:29061364)

PMID:15459207 PMID:15459207

PMID:29061364

MGI:6304699

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Map2k1

mitogen activated protein kinase kinase 1

involved_in

IMP
IGI

PMID:15459207

CAFA

RGD:12793039, RGD:12793039

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

Myc

MYC proto-oncogene, bHLH transcription factor

RGD

PMID:22629444

RGD:7240532

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

Ndufc2

NADH:ubiquinone oxidoreductase subunit C2

RGD

PMID:26888427

RGD:11040458

NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189

Pid1

phosphotyrosine interaction domain containing 1

involved_in

(MGI:5306739|PMID:21080215)

PMID:21080215

MGI:5306739

NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044

Ppara

peroxisome proliferator activated receptor alpha

acts_upstream_of

(PMID:31574452)

PMID:31574452

NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346

Ppargc1a

PPARG coactivator 1 alpha

involved_in

GO_REF:0000024
(MGI:5463828|PMID:23150719)

PMID:23150719

GO_REF:0000024 MGI:5463828

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

Prkn

parkin RBR E3 ubiquitin protein ligase

RGD

PMID:24096089

RGD:10413842

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

Sirt1

sirtuin 1

involved_in

(PMID:24747689)

PMID:24747689

NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260

Slc25a12

solute carrier family 25 member 12

RGD

PMID:19764902

RGD:13628741

NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100

Stat3

signal transducer and activator of transcription 3

RGD

PMID:23590160

RGD:8694322

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

Tafazzin

tafazzin, phospholipid-lysophospholipid transacylase

RGD

PMID:20348225

RGD:13432160

NCBI chr X:152,065,539...152,076,178
Ensembl chr X:152,065,609...152,074,001

Tmsb4x

thymosin beta 4, X-linked

involved_in

(PMID:21106936)

PMID:21106936

NCBI chr X:27,144,677...27,146,667
Ensembl chr X:27,128,610...27,146,667

Trem2

triggering receptor expressed on myeloid cells 2

involved_in

(MGI:5906931|PMID:28802038)

PMID:28802038

MGI:5906931

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

Vcp

valosin-containing protein

involved_in

(PMID:23498975)

PMID:23498975

NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571

positive regulation of ATP metabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bend3

BEN domain containing 3

involved_in

(PMID:28977671)

PMID:28977671

NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671

positive regulation of cAMP-dependent protein kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenylate cyclase 10

RGD

NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951

Adipoq

adiponectin, C1Q and collagen domain containing

involved_in

(PMID:18431508), (PMID:19524870)
GO_REF:0000024
(MGI:3795840|PMID:18431508)

PMID:18431508 PMID:19524870

GO_REF:0000024 MGI:3795840

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

Akap6

A-kinase anchoring protein 6

involved_in

PMID:11179196

BHF-UCL

PMID:11179196

RGD:8553373

NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738

Atp2b4

ATPase plasma membrane Ca2+ transporting 4

involved_in

(PMID:19278978)

PMID:19278978

NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246

Rapgef2

Rap guanine nucleotide exchange factor 2

involved_in

GO_REF:0000024
(MGI:5499726|PMID:16272156)
(PMID:16272156)

PMID:16272156

GO_REF:0000024 MGI:5499726

NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247

Sirt1

sirtuin 1

involved_in

(PMID:18687677)
(MGI:5306579|PMID:18687677)

PMID:18687677

MGI:5306579

NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260

Spatc1l

spermatogenesis and centriole associated 1-like

acts_upstream_of_or_within

(MGI:6199287|PMID:30026308)

PMID:30026308

MGI:6199287

NCBI chr20:12,074,040...12,083,873
Ensembl chr20:12,074,047...12,083,301

positive regulation of cardiolipin metabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tafazzin

tafazzin, phospholipid-lysophospholipid transacylase

RGD

PMID:20348225

RGD:13432160

NCBI chr X:152,065,539...152,076,178
Ensembl chr X:152,065,609...152,074,001

positive regulation of cyclin-dependent protein kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hsp90ab1

heat shock protein 90 alpha family class B member 1

involved_in

IMP
ISO

PMID:17517623
(MGI:6148636|PMID:17517623)

PMID:17517623 PMID:17517623

MGI:6148636, RGD:13514081

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

Stox1

storkhead box 1

involved_in

(PMID:22253775), (PMID:22995177)

PMID:22253775 PMID:22995177

NCBI chr20:30,598,656...30,666,371
Ensembl chr20:30,598,168...30,666,939

Ttbk1

tau tubulin kinase 1

involved_in

(PMID:19118186)

PMID:19118186

NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774

positive regulation of cyclin-dependent protein serine/threonine kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adam17

ADAM metallopeptidase domain 17

involved_in

(PMID:18483258)

PMID:18483258

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

Akt1

AKT serine/threonine kinase 1

involved_in

(PMID:18483258)

PMID:18483258

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Ccnd1

cyclin D1

involved_in

GO_REF:0000024
(PMID:8114739)

PMID:8114739

GO_REF:0000024

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

Ccnd2

cyclin D2

involved_in

(PMID:8114739)

PMID:8114739

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

Ccnd3

cyclin D3

involved_in

(PMID:8114739)
GO_REF:0000107

PMID:8114739

GO_REF:0000107

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

Ccny

cyclin Y

involved_in

(PMID:19524571), (PMID:20059949)

PMID:19524571 PMID:20059949

NCBI chr17:57,385,002...57,512,860
Ensembl chr17:57,384,176...57,522,378

Cdc6

cell division cycle 6

RGD

PMID:22223646

RGD:10045360

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

Cdk5rap1

CDK5 regulatory subunit associated protein 1

RGD

PMID:10721722

RGD:632478

NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677

Cdkn1b

cyclin-dependent kinase inhibitor 1B

RGD

PMID:22223646

RGD:10045360

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

epidermal growth factor receptor

involved_in

(PMID:18483258)

PMID:18483258

NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382

Gdf9

growth differentiation factor 9

involved_in

(PMID:24313324)

PMID:24313324

NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672

Mapre3

microtubule-associated protein, RP/EB family, member 3

involved_in

(MGI:3773778|PMID:17310996)

PMID:17310996

MGI:3773778

NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881

Mnat1

MNAT1 component of CDK activating kinase

involved_in

IEA

GO_REF:0000002

InterPro

GO_REF:0000002

NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744

platelet derived growth factor subunit B

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:16530387)

UniProt
Ensembl
RGD

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

Pim1

Pim-1 proto-oncogene, serine/threonine kinase

involved_in

(PMID:18593906)

PMID:18593906

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

Pkd1

polycystin 1, transient receptor potential channel interacting

involved_in

(PMID:16311606)

PMID:16311606

NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128

Pkd2

polycystin 2, transient receptor potential cation channel

involved_in

(PMID:16311606)

PMID:16311606

NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825

Prox1

prospero homeobox 1

involved_in

(PMID:19210544)

PMID:19210544

NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183

Psmd10

proteasome 26S subunit, non-ATPase 10

involved_in

(PMID:11900540)
GO_REF:0000024

PMID:11900540

GO_REF:0000024

NCBI chr X:104,656,809...104,665,126
Ensembl chr X:104,656,812...104,665,097

Psrc1

proline and serine rich coiled-coil 1

involved_in

(MGI:3773778|PMID:17310996)

PMID:17310996

MGI:3773778

NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874

Rgcc

regulator of cell cycle

involved_in

(PMID:11687586), (PMID:19162005)

PMID:11687586 PMID:19162005

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

Spdya

speedy/RINGO cell cycle regulator family member A

involved_in

ISS
ISO
IBA

GO_REF:0000024
(PMID:17151349)
(MGI:3617485|PMID:15611625)
PMID:21873635

PMID:15611625 PMID:17151349 PMID:21873635

GO_REF:0000024 MGI:3617485, RGD:13792537

NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850

Spdye4c

speedy/RINGO cell cycle regulator family, member E4C

involved_in

IEA

GO_REF:0000002

InterPro

GO_REF:0000002

NCBI chr 3:115,830,999...115,838,358
Ensembl chr 3:115,831,090...115,838,354

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in

PMID:16530387

UniProt

RGD:8553998

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

Stil

STIL, centriolar assembly protein

acts_upstream_of_or_within

(MGI:3586393|PMID:16024801)

PMID:16024801

MGI:3586393

NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730

positive regulation of dephosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Igbp1

immunoglobulin binding protein 1

involved_in

(MGI:3056248|PMID:15499020)

PMID:15499020

MGI:3056248

NCBI chr X:65,582,832...65,605,078
Ensembl chr X:65,582,821...65,606,049

Rock1

Rho-associated coiled-coil containing protein kinase 1

involved_in

(PMID:27221467)

PMID:27221467

NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in

(PMID:23159740)

PMID:23159740

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ppp1r15a

protein phosphatase 1, regulatory subunit 15A

involved_in

(PMID:21518769)

PMID:21518769

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

positive regulation of epidermal growth factor-activated receptor activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adam17

ADAM metallopeptidase domain 17

involved_in

(PMID:17655843), (PMID:18483258)

PMID:17655843 PMID:18483258

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

Adora1

adenosine A1 receptor

RGD

PMID:19574994

RGD:2317913

NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801

adrenoceptor alpha 2A

involved_in

(PMID:17655843)

PMID:17655843

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

Areg

amphiregulin

involved_in

PMID:21873635

GO_Central

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

Btc

betacellulin

involved_in

PMID:21873635

GO_Central

NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049

Egf

epidermal growth factor

involved_in

(PMID:15611079), (PMID:20353436), (PMID:22732145)
GO_REF:0000107

PMID:15611079 PMID:20353436 PMID:22732145

GO_REF:0000107

NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064

Epgn

epithelial mitogen

involved_in

ISS
ISO
IBA

GO_REF:0000024
(MGI:1934957|PMID:11278323)
PMID:21873635
(PMID:15611079)

HGNC-UCL
RGD

PMID:11278323 PMID:15611079 PMID:21873635

GO_REF:0000024 MGI:1934957, RGD:13792537

NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806

Ereg

epiregulin

involved_in

IBA
IDA

PMID:21873635
PMID:9990076

GO_Central
UniProt

PMID:21873635 PMID:9990076

RGD:13792537, RGD:632743

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

Fbxw7

F-box and WD repeat domain containing 7

involved_in

(PMID:20208556)

PMID:20208556

NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941

Hbegf

heparin-binding EGF-like growth factor

involved_in

PMID:21873635

GO_Central

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

Ncf1

neutrophil cytosolic factor 1

involved_in

(PMID:26514923)

PMID:26514923

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

Neurl1

neuralized E3 ubiquitin protein ligase 1

acts_upstream_of_or_within

MGI:2152037 (MGI:2149168|PMID:11481456)

PMID:11278323 PMID:21873635

PMID:11481456

MGI:2149168

NCBI chr 1:246,066,642...246,152,890
Ensembl chr 1:246,067,100...246,152,903

Tgfa

transforming growth factor alpha

involved_in

IBA
ISS
ISO

PMID:21873635
GO_REF:0000024
(PMID:11278323)

HGNC-UCL
RGD

GO_REF:0000024, RGD:13792537

NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894

positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ifng

interferon gamma

involved_in

(PMID:9282826)

PMID:9282826

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

positive regulation of fructose 1,6-bisphosphate metabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ifng

interferon gamma

involved_in

(PMID:9282826)

PMID:9282826

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

positive regulation of glucokinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bad

BCL2-associated agonist of cell death

involved_in

GO_REF:0000024
(MGI:3778846|PMID:18223655)

PMID:18223655

GO_REF:0000024 MGI:3778846

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

Dusp12

dual specificity phosphatase 12

increases glucokinase activity by direct dephosphorylation

RGD

PMID:10913113

RGD:68242

NCBI chr13:83,122,192...83,131,800
Ensembl chr13:83,122,193...83,131,285

Gckr

glucokinase regulator

involved_in

(MGI:1354534|PMID:10713097)

PMID:10713097

MGI:1354534

NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654

Pfkfb1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

RGD

PMID:15047617

RGD:2302684

NCBI chr X:19,508,522...19,562,165
Ensembl chr X:19,508,546...19,562,182

Pfkfb2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

RGD

PMID:16980436

RGD:2304071

NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699

Ranbp2

RAN binding protein 2

acts_upstream_of_or_within

(MGI:3693040|PMID:17069463)

PMID:17069463

MGI:3693040

NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481

positive regulation of guanylate cyclase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adora2b

adenosine A2B receptor

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3773754 (MGI:3794903|PMID:18340377)

PMID:12545196 PMID:21873635

PMID:18340377

GO_REF:0000107 MGI:3794903

NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772

Guca1a

guanylate cyclase activator 1A

involved_in

IDA
IBA

PMID:21873635

RGD
GO_Central

RGD:1599357, RGD:13792537

NCBI chr 9:13,587,695...13,598,566
Ensembl chr 9:13,588,525...13,598,565

Nos1

nitric oxide synthase 1

involved_in

PMID:21873635

GO_Central

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

Nos2

nitric oxide synthase 2

involved_in

PMID:21873635

GO_Central

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

Nos3

nitric oxide synthase 3

involved_in

ISO
IBA
IEA

(PMID:17502619)
PMID:21873635
GO_REF:0000107

PMID:17502619 PMID:21873635

GO_REF:0000107, RGD:13792537

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

positive regulation of hexokinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tigar

TP53 induced glycolysis regulatory phosphatase

involved_in

(PMID:23185017)

PMID:23185017

NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029

positive regulation of I-kappaB phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Akt1

AKT serine/threonine kinase 1

involved_in

(PMID:26514923)

PMID:26514923

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Cx3cl1

C-X3-C motif chemokine ligand 1

involved_in

UniProtKB:P35411 (PMID:10869418)
GO_REF:0000107

PMID:10869418

GO_REF:0000107

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

Cx3cr1

C-X3-C motif chemokine receptor 1

involved_in

IGI

PMID:10869418

ARUK-UCL

PMID:10869418

RGD:4892026

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

Ddrgk1

DDRGK domain containing 1

involved_in

(PMID:23675531)

PMID:23675531

NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680

Plcg2

phospholipase C, gamma 2

involved_in

(MGI:5300086|PMID:22041900)
GO_REF:0000107

PMID:22041900

GO_REF:0000107 MGI:5300086

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

tumor necrosis factor

acts_upstream_of_or_within

(PMID:31124343)

PMID:31124343

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

positive regulation of inhibitory G protein-coupled receptor phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aplnr

apelin receptor

involved_in

GO_REF:0000024
(PMID:25639753)

PMID:25639753

GO_REF:0000024

NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050

Ptger3

prostaglandin E receptor 3

RGD

PMID:15937517

RGD:10043344

NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434

positive regulation of inositol phosphate biosynthetic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcyap1r1

ADCYAP receptor type I

RGD

PMID:8943280

RGD:2315982

NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700

Avpr1b

arginine vasopressin receptor 1B

involved_in

(PMID:9322919)
GO_REF:0000107

PMID:9322919

GO_REF:0000107

NCBI chr13:43,046,960...43,057,110
Ensembl chr13:43,046,267...43,057,792

Cd244

CD244 molecule

involved_in

(PMID:8376943)

PMID:8376943

NCBI chr13:84,018,887...84,036,612
Ensembl chr13:84,020,095...84,036,100

Mas1

MAS1 proto-oncogene, G protein-coupled receptor

RGD

PMID:1332507

RGD:2316794

NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709

Ntsr1

neurotensin receptor 1

RGD

PMID:11861328

RGD:9743897

NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377

Ptafr

platelet-activating factor receptor

RGD

PMID:8798508

RGD:9999203

NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251

Pth

parathyroid hormone

involved_in

(PMID:11604398)

PMID:11604398

NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530

Pth1r

parathyroid hormone 1 receptor

involved_in

PMID:19608645

BHF-UCL

PMID:19608645

RGD:8553376

NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729

Snca

synuclein alpha

involved_in

(PMID:15641770)

PMID:15641770

NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262

positive regulation of inositol trisphosphate biosynthetic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gper1

G protein-coupled estrogen receptor 1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:15705806)

UniProt
Ensembl
RGD

PMID:15705806

GO_REF:0000024 GO_REF:0000107

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

Lhcgr

luteinizing hormone/choriogonadotropin receptor

involved_in

GO_REF:0000107
(MGI:5318037|PMID:10493819)

PMID:10493819

GO_REF:0000107 MGI:5318037

NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521

Myh9

myosin, heavy chain 9

RGD

PMID:20068007

RGD:6902910

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

P2ry1

purinergic receptor P2Y1

involved_in

PMID:11390975

BHF-UCL

PMID:11390975

RGD:8553380

NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457

P2ry6

pyrimidinergic receptor P2Y6

involved_in

(PMID:8670200)

PMID:8670200

NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808

Plcd1

phospholipase C, delta 1

RGD

PMID:16709602

RGD:2300424

NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186

Pou1f1

POU class 1 homeobox 1

acts_upstream_of_or_within

MGI:1856024|MGI:1856025 (MGI:2135699|PMID:11371619)

PMID:11371619

MGI:2135699

NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801

positive regulation of inositol-polyphosphate 5-phosphatase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Plek

pleckstrin

involved_in

(PMID:8999861)

PMID:8999861

NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131

positive regulation of JUN kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ager

advanced glycosylation end product-specific receptor

acts_upstream_of_or_within

MGI:2451038 (MGI:3847400|PMID:18323529)

PMID:18323529

MGI:3847400

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

Arhgef5

Rho guanine nucleotide exchange factor 5

involved_in

(PMID:15601624)

PMID:15601624

NCBI chr 4:72,087,205...72,112,316
Ensembl chr 4:72,087,247...72,111,254

axin 1

acts_upstream_of_or_within

(MGI:2675921|PMID:12878610), (MGI:3573812|PMID:15579909)

PMID:12878610 PMID:15579909

MGI:2675921 MGI:3573812

NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615

Ccl19

C-C motif chemokine ligand 19

acts_upstream_of

(MGI:5284790|PMID:16027136)

PMID:16027136

MGI:5284790

NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308

Dab2ip

DAB2 interacting protein

involved_in

(MGI:3796479|PMID:18281285)
(PMID:12813029), (PMID:15310755)

PMID:12813029 PMID:15310755 PMID:18281285

MGI:3796479

NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280

Dkk1

dickkopf WNT signaling pathway inhibitor 1

involved_in

(PMID:23164821)

PMID:23164821

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

Dusp19

dual specificity phosphatase 19

involved_in

(MGI:2182169|PMID:11959862)

PMID:11959862

MGI:2182169

NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534

Dvl2

dishevelled segment polarity protein 2

involved_in

(PMID:17593335), (PMID:19137009)
(MGI:4835155|PMID:10829020)

PMID:10829020 PMID:17593335 PMID:19137009

MGI:4835155

NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820

Dvl3

dishevelled segment polarity protein 3

involved_in

(PMID:19137009)

PMID:19137009

NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462

Edn1

endothelin 1

involved_in

(PMID:12847114)

PMID:12847114

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

Epha4

Eph receptor A4

involved_in

(MGI:1890011|PMID:10523642)

PMID:10523642

MGI:1890011

NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139

Ern1

endoplasmic reticulum to nucleus signaling 1

involved_in

(PMID:10650002)
(MGI:3777353|PMID:10650002)

PMID:10650002

MGI:3777353

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

Ern2

endoplasmic reticulum to nucleus signaling 2

involved_in

(MGI:3777353|PMID:10650002)

PMID:10650002

MGI:3777353

NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289

Fcer1a

Fc epsilon receptor Ia

acts_upstream_of_or_within

(MGI:85068|PMID:9000133)

PMID:9000133

MGI:85068

NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351

Fgd2

FYVE, RhoGEF and PH domain containing 2

acts_upstream_of_or_within

MGI:106211 (MGI:3828237|PMID:18838382)

PMID:18838382

MGI:3828237

NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603

Fgd4

FYVE, RhoGEF and PH domain containing 4

acts_upstream_of_or_within

PMID:9668039

MGI

PMID:9668039

RGD:1299389

NCBI chr11:84,399,885...84,551,013
Ensembl chr11:84,399,816...84,546,972

Fzd10

frizzled class receptor 10

involved_in

(PMID:19137009)

PMID:19137009

NCBI chr12:28,098,371...28,101,566
Ensembl chr12:28,098,371...28,101,566

Fzd4

frizzled class receptor 4

acts_upstream_of_or_within

MGI:1923484|MGI:2135272 (MGI:4829604|PMID:15195140)

NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724

Fzd5

frizzled class receptor 5

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:4829604|PMID:15195140)

GO_REF:0000107 MGI:4829604

NCBI chr 9:66,117,370...66,119,127
Ensembl chr 9:66,113,112...66,121,457

Fzd8

frizzled class receptor 8

acts_upstream_of_or_within

(MGI:4829604|PMID:15195140)

NCBI chr17:57,312,924...57,320,551
Ensembl chr17:57,314,450...57,320,650

interleukin 1 beta

RGD

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il1rn

interleukin 1 receptor antagonist

RGD

PMID:12667655

RGD:1626684

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

Irak1

interleukin-1 receptor-associated kinase 1

involved_in

(MGI:3843426|PMID:17379480)

PMID:17379480

MGI:3843426

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Magi3

membrane associated guanylate kinase, WW and PDZ domain containing 3

acts_upstream_of_or_within

MGI:108520|MGI:2135272 (MGI:4829604|PMID:15195140)

NCBI chr 2:191,514,726...191,717,048
Ensembl chr 2:191,518,506...191,716,735

Map2k7

mitogen activated protein kinase kinase 7

involved_in

(MGI:2182169|PMID:11959862)

PMID:11959862

MGI:2182169

NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222

Map3k1

mitogen-activated protein kinase kinase kinase 1

involved_in

IDA
ISO

(MGI:1890011|PMID:10523642)

PMID:10523642 PMID:9110999

MGI:1890011, RGD:2293488

NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463

Map3k10

mitogen activated protein kinase kinase kinase 10

involved_in

(PMID:17584736)

PMID:17584736

NCBI chr 1:82,955,783...82,974,084
Ensembl chr 1:82,955,207...82,974,084

Map3k11

mitogen-activated protein kinase kinase kinase 11

involved_in

(PMID:17584736)

PMID:17584736

NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652

Map3k12

mitogen activated protein kinase kinase kinase 12

involved_in

(MGI:5810221|PMID:27511108)
GO_REF:0000107

PMID:27511108

GO_REF:0000107 MGI:5810221

NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789

Map3k13

mitogen-activated protein kinase kinase kinase 13

involved_in

(MGI:5810221|PMID:27511108)

PMID:27511108

MGI:5810221

NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181

Map3k4

mitogen activated protein kinase kinase kinase 4

involved_in
acts_upstream_of_or_within

(PMID:9305639)
(MGI:4821077|PMID:16157600)
(MGI:2675921|PMID:12878610)

PMID:9305639 PMID:12878610 PMID:16157600

MGI:2675921 MGI:4821077

NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358

Map3k5

mitogen-activated protein kinase kinase kinase 5

involved_in

IMP
ISO

(PMID:23000344)

PMID:23000344 PMID:20716917

RGD:10412640

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

Map3k7

mitogen activated protein kinase kinase kinase 7

involved_in

ISO
IEA
ISS

(PMID:10094049), (PMID:11460167)
GO_REF:0000104
GO_REF:0000024

PMID:10094049 PMID:11460167

GO_REF:0000024 GO_REF:0000104

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

Map4k2

mitogen activated protein kinase kinase kinase kinase 2

involved_in

(PMID:17584736)

PMID:17584736

NCBI chr 1:203,645,098...203,660,515
Ensembl chr 1:203,645,153...203,660,331

Mapk8ip3

mitogen-activated protein kinase 8 interacting protein 3

involved_in
acts_upstream_of_or_within

(MGI:1890011|PMID:10523642)
(MGI:3575843|PMID:15767678)

PMID:10523642 PMID:15767678

MGI:1890011 MGI:3575843

NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273

Mir92a1

microRNA 92a-1

involved_in

(PMID:24332650)

PMID:24332650

NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413

Mir92a2

microRNA 92a-2

involved_in

(PMID:24332650)

PMID:24332650

NCBI chr X:132,421,942...132,422,033
Ensembl chr X:132,421,942...132,422,033

Pak1

p21 (RAC1) activated kinase 1

involved_in

(PMID:8805275)
GO_REF:0000024

PMID:8805275 PMID:8805275

GO_REF:0000024, RGD:8554570

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

Ptk2b

protein tyrosine kinase 2 beta

RGD

PMID:15226266

RGD:1642623

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

Ptpn1

protein tyrosine phosphatase, non-receptor type 1

acts_upstream_of

(MGI:5616322|PMID:15465829)

PMID:15465829

MGI:5616322

NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504

Ror2

receptor tyrosine kinase-like orphan receptor 2

RGD

PMID:25825749

RGD:11537351

NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152

Rps3

ribosomal protein S3

involved_in

(PMID:22510408)

PMID:22510408

NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680

Sash1

SAM and SH3 domain containing 1

acts_upstream_of_or_within
involved_in

(PMID:23776175)
PMID:21873635

PMID:23776175 PMID:21873635

NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870

Syk

spleen associated tyrosine kinase

acts_upstream_of_or_within
involved_in

MGI:2384078 (MGI:85068|PMID:9000133)
GO_REF:0000107

PMID:9000133

GO_REF:0000107 MGI:85068

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

Taok3

TAO kinase 3

involved_in

(PMID:11278723)
GO_REF:0000107

PMID:11278723

GO_REF:0000107

NCBI chr12:39,314,027...39,394,243
Ensembl chr12:39,314,027...39,461,244

Tiam1

TIAM Rac1 associated GEF 1

RGD

PMID:16203995

RGD:10043312

NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901

Tlr6

toll-like receptor 6

acts_upstream_of_or_within

(PMID:10231569)

PMID:10231569

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

Tlr9

toll-like receptor 9

involved_in

(PMID:17128265)

PMID:17128265

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

tumor necrosis factor

involved_in

(PMID:17389591)

PMID:17389591

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tnfrsf11a

TNF receptor superfamily member 11A

involved_in

(PMID:12296995)

PMID:12296995

NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695

Traf2

Tnf receptor-associated factor 2

involved_in

(PMID:11907583)

PMID:11907583

NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538

Traf6

TNF receptor associated factor 6

involved_in

(PMID:11751921)

PMID:11751921

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

Vangl2

VANGL planar cell polarity protein 2

acts_upstream_of_or_within

MGI:108520|MGI:1923484 (MGI:4829604|PMID:15195140)

NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378

Wnt family member 5A

acts_upstream_of_or_within

MGI:1857617 (MGI:3839161|PMID:19300477)
(PMID:20032469), (PMID:20034610)

PMID:19300477 PMID:20032469 PMID:20034610

MGI:3839161

NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234

Zeb2

zinc finger E-box binding homeobox 2

acts_upstream_of_or_within

MGI:2387499|MGI:2684610 (MGI:3718270|PMID:17644613)

PMID:17644613

MGI:3718270

NCBI chr 3:29,219,765...29,342,094
Ensembl chr 3:29,218,301...29,345,157

positive regulation of kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ajuba

ajuba LIM protein

acts_upstream_of_or_within

(MGI:3581335|PMID:15870270)

PMID:15870270

MGI:3581335

NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021

Alk

ALK receptor tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034

Axl

Axl receptor tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265

Cd4

Cd4 molecule

involved_in

(PMID:24942581)

PMID:24942581

NCBI chr 4:157,668,878...157,695,366

Cd44

CD44 molecule (Indian blood group)

involved_in

(PMID:11084024)

PMID:11084024

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

Cd74

CD74 molecule

involved_in

(PMID:24942581)
PMID:21873635

PMID:24942581 PMID:21873635

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

Cimap3

ciliary microtubule associated protein 3

involved_in

(PMID:20643351)

PMID:20643351

NCBI chr 2:193,475,785...193,493,092
Ensembl chr 2:193,475,782...193,493,139

Csf1r

colony stimulating factor 1 receptor

involved_in

PMID:21873635

GO_Central

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

Ddr1

discoidin domain receptor tyrosine kinase 1

involved_in

PMID:21873635

GO_Central

NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468

Ddr2

discoidin domain receptor tyrosine kinase 2

involved_in

PMID:21873635

GO_Central

NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363

Drd4

dopamine receptor D4

involved_in

(PMID:15755724)

PMID:15755724

NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553

Dstyk

dual serine/threonine and tyrosine protein kinase

involved_in

(PMID:23862974)
GO_REF:0000024

PMID:23862974

GO_REF:0000024

NCBI chr13:43,857,266...43,905,280
Ensembl chr13:43,857,266...43,905,269

epidermal growth factor receptor

involved_in

PMID:21873635

GO_Central

NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382

Epha1

Eph receptor A1

involved_in

PMID:21873635

GO_Central

NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846

Epha2

Eph receptor A2

involved_in

PMID:21873635

GO_Central

NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117

Epha6

Eph receptor A6

involved_in

PMID:21873635

GO_Central

NCBI chr11:39,757,870...40,708,901
Ensembl chr11:39,757,181...40,698,311

Epha8

Eph receptor A8

involved_in

PMID:21873635

GO_Central

NCBI chr 5:149,166,107...149,193,498
Ensembl chr 5:149,166,697...149,193,399

Ephb4

EPH receptor B4

involved_in

PMID:21873635

GO_Central

NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314

Erbb2

erb-b2 receptor tyrosine kinase 2

involved_in

PMID:21873635

GO_Central

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

Erbb3

erb-b2 receptor tyrosine kinase 3

involved_in

PMID:21873635

GO_Central

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

Erbb4

erb-b2 receptor tyrosine kinase 4

involved_in

PMID:21873635

GO_Central

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

Fgfr1

Fibroblast growth factor receptor 1

involved_in

PMID:21873635

GO_Central

NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350

Fgfr2

fibroblast growth factor receptor 2

involved_in

PMID:21873635

GO_Central

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

Fgfr3

fibroblast growth factor receptor 3

involved_in

PMID:21873635

GO_Central

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

Fgfr4

fibroblast growth factor receptor 4

involved_in

PMID:21873635

GO_Central

NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242

Flt1

Fms related receptor tyrosine kinase 1

involved_in

PMID:21873635

GO_Central

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

Flt3

Fms related receptor tyrosine kinase 3

involved_in

PMID:21873635

GO_Central

NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474

Flt4

Fms related receptor tyrosine kinase 4

involved_in

PMID:21873635

GO_Central

NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770

Igf1r

insulin-like growth factor 1 receptor

involved_in

PMID:21873635

GO_Central

NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777

insulin receptor

involved_in

PMID:21873635

GO_Central

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

Insrr

insulin receptor-related receptor

involved_in

PMID:21873635

GO_Central

NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800

Kdr

kinase insert domain receptor

involved_in

PMID:21873635

GO_Central

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

Lmo4

LIM domain only 4

involved_in

(MGI:5751633|PMID:25882817)

PMID:25882817

MGI:5751633

NCBI chr 2:233,264,180...233,280,881
Ensembl chr 2:233,264,182...233,280,880

Ltk

leukocyte receptor tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 3:106,734,675...106,741,552
Ensembl chr 3:106,734,676...106,743,369

Mertk

MER proto-oncogene, tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554

Met

MET proto-oncogene, receptor tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

Mre11

MRE11 homolog, double strand break repair nuclease

involved_in

(PMID:15790808)
GO_REF:0000107

PMID:15790808

GO_REF:0000107

NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279

Mst1r

macrophage stimulating 1 receptor

involved_in

PMID:21873635

GO_Central

NCBI chr 8:108,596,100...108,611,389
Ensembl chr 8:108,597,299...108,612,455

Musk

muscle associated receptor tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932

Nbn

nibrin

involved_in

GO_REF:0000107
(PMID:15790808)

PMID:15790808

GO_REF:0000107

NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150

Ntrk1

neurotrophic receptor tyrosine kinase 1

involved_in

PMID:21873635

GO_Central

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

Ntrk2

neurotrophic receptor tyrosine kinase 2

involved_in

PMID:21873635

GO_Central

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

neurotrophic receptor tyrosine kinase 3

involved_in

PMID:21873635

GO_Central

NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286

Pdgfra

platelet derived growth factor receptor alpha

involved_in

PMID:21873635

GO_Central

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

Pdgfrb

platelet derived growth factor receptor beta

involved_in

PMID:21873635

GO_Central

NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843

Rad50

RAD50 double strand break repair protein

involved_in

(PMID:15790808)
GO_REF:0000107

PMID:15790808

GO_REF:0000107

NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396

Ret

ret proto-oncogene

involved_in

PMID:21873635

GO_Central

NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176

Ror1

receptor tyrosine kinase-like orphan receptor 1

involved_in

PMID:21873635

GO_Central

NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155

Ror2

receptor tyrosine kinase-like orphan receptor 2

involved_in

PMID:21873635

GO_Central

NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152

Ros1

ROS proto-oncogene 1 , receptor tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865

RT1-Db1

RT1 class II, locus Db1

involved_in

(PMID:24942581)

PMID:24942581

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

Ryk

receptor-like tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 8:103,419,348...103,492,083
Ensembl chr 8:103,419,275...103,491,698

Tek

TEK receptor tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804

Tie1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

involved_in

PMID:21873635

GO_Central

NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592

Trem2

triggering receptor expressed on myeloid cells 2

involved_in

(PMID:31902528)

PMID:31902528

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

Tyro3

TYRO3 protein tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142

Vac14

VAC14 component of PIKFYVE complex

involved_in

PMID:21873635

GO_Central

NCBI chr19:38,590,569...38,691,911
Ensembl chr19:38,590,569...38,691,909

Zfp622

zinc finger protein 622

involved_in

(PMID:21771788)

PMID:21771788

NCBI chr 2:76,479,605...76,494,405
Ensembl chr 2:76,335,609...76,493,898

Znf16l-ps1

Zinc finger protein 16 like, pseudogene 1

involved_in

(PMID:21874239)

PMID:21874239

NCBI chr 7:108,650,694...108,670,246

positive regulation of lipid kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Eef1a2

eukaryotic translation elongation factor 1 alpha 2

involved_in

(PMID:17088255)

PMID:17088255

NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071

coagulation factor II

involved_in

GO_REF:0000107
(PMID:11309392)

PMID:11309392

GO_REF:0000107

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

positive regulation of MAP kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adam8

ADAM metallopeptidase domain 8

involved_in

(MGI:5009349|PMID:20683884)

PMID:20683884

MGI:5009349

NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801

Adam9

ADAM metallopeptidase domain 9

acts_upstream_of

(PMID:17704059)

PMID:17704059

NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917

adrenoceptor alpha 2A

involved_in

(PMID:19477270)

PMID:19477270

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

Ajuba

ajuba LIM protein

acts_upstream_of_or_within

(MGI:1336980|PMID:10330178)

PMID:10330178

MGI:1336980

NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021

Akap13

A-kinase anchoring protein 13

involved_in

PMID:11404397 PMID:11404397

PMID:23716597

UniProt

PMID:23716597

RGD:11059588

NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646

App

amyloid beta precursor protein

involved_in

IGI
IDA

PMID:11404397

ARUK-UCL

RGD:12790656, RGD:12790656

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

Cd24

CD24 molecule

involved_in

GO_REF:0000024
PMID:12496407
(PMID:12496407)

PMID:12496407 PMID:12496407

GO_REF:0000024, RGD:8554185

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

Cd40

CD40 molecule

involved_in

(PMID:21410936)

PMID:21410936

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

Ceacam1

CEA cell adhesion molecule 1

acts_upstream_of_or_within

PMID:11994468

MGI

PMID:11994468

RGD:625644

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

Csk

C-terminal Src kinase

RGD

PMID:10884975

RGD:5134370

NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292

Diras1

DIRAS family GTPase 1

NOT|involved_in

(PMID:12194967)

PMID:12194967

NCBI chr 7:8,687,964...8,692,828
Ensembl chr 7:8,687,942...8,693,831

Diras2

DIRAS family GTPase 2

NOT|involved_in

(PMID:12194967)

PMID:12194967

NCBI chr17:12,730,040...12,761,511
Ensembl chr17:12,725,149...12,761,663

Drd4

dopamine receptor D4

acts_upstream_of
involved_in

(PMID:9843378)
GO_REF:0000107
(PMID:15755724)

PMID:9843378 PMID:15755724

GO_REF:0000107

NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553

Edn1

endothelin 1

involved_in

(PMID:10770212), (PMID:12847114)

PMID:10770212 PMID:12847114

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

Edn3

endothelin 3

involved_in

(PMID:10770212)

PMID:10770212

NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093

Egf

epidermal growth factor

involved_in

(PMID:15611079)
GO_REF:0000107

PMID:15611079

GO_REF:0000107

NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064

epidermal growth factor receptor

involved_in

(PMID:10572067)

PMID:10572067

NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382

Epgn

epithelial mitogen

involved_in
acts_upstream_of

PMID:11278323 PMID:15611079

GO_REF:0000024
(MGI:1934957|PMID:11278323)
(PMID:15611079)

HGNC-UCL
RGD

GO_REF:0000024 MGI:1934957

NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806

Erbb2

erb-b2 receptor tyrosine kinase 2

involved_in

(PMID:10572067)

PMID:10572067

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

Erp29

endoplasmic reticulum protein 29

acts_upstream_of_or_within

(PMID:22064321)

PMID:22064321

NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376

Ezh2

enhancer of zeste 2 polycomb repressive complex 2 subunit

involved_in

(PMID:20154697)

PMID:20154697

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

Fcer1a

Fc epsilon receptor Ia

acts_upstream_of_or_within

(MGI:85068|PMID:9000133)

PMID:9000133

MGI:85068

NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351

Fgf1

fibroblast growth factor 1

involved_in

(PMID:16756958)

PMID:16756958

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

Fgf18

fibroblast growth factor 18

involved_in

(PMID:16756958)
GO_REF:0000107

PMID:16756958

GO_REF:0000107

NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818

Fgf2

fibroblast growth factor 2

involved_in

(PMID:16756958)

PMID:16756958

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

Fgfr1

Fibroblast growth factor receptor 1

involved_in

GO_REF:0000024
(PMID:18480409), (PMID:8622701)

PMID:8622701 PMID:18480409

GO_REF:0000024

NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350

Flt1

Fms related receptor tyrosine kinase 1

involved_in

(PMID:9299537)
GO_REF:0000107

PMID:9299537

GO_REF:0000107

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

Gab1

GRB2-associated binding protein 1

acts_upstream_of_or_within

MGI:2667211 (MGI:2664443|PMID:12808090)

PMID:12808090

MGI:2664443

NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236

Gdf9

growth differentiation factor 9

involved_in

(PMID:24313324)

PMID:24313324

NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672

Ghr

growth hormone receptor

acts_upstream_of

PMID:8063815

BHF-UCL

PMID:8063815

RGD:8553732

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

Gpr39

G protein-coupled receptor 39

acts_upstream_of_or_within

(MGI:5707553|PMID:26375174)

PMID:26375174

MGI:5707553

NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267

Hras

HRas proto-oncogene, GTPase

involved_in

(PMID:23027131)

PMID:23027131

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

Htr2a

5-hydroxytryptamine receptor 2A

RGD

PMID:15087293

RGD:1624373

NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928

Htr2b

5-hydroxytryptamine receptor 2B

involved_in

GO_REF:0000107
(PMID:15625277)

PMID:15625277

GO_REF:0000107

NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108

Il1b

interleukin 1 beta

acts_upstream_of

(PMID:10748004)

PMID:10748004

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il34

interleukin 34

acts_upstream_of_or_within
involved_in

(PMID:26754294)
GO_REF:0000107

PMID:26754294

GO_REF:0000107

NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000

Ilk

integrin-linked kinase

inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation

RGD

PMID:17182785

RGD:2301767

NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140

insulin receptor

acts_upstream_of

(PMID:17001305)

PMID:17001305

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

Iqgap1

IQ motif containing GTPase activating protein 1

RGD

PMID:23987506

RGD:11049533

NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755

Irak1

interleukin-1 receptor-associated kinase 1

involved_in

(MGI:3843426|PMID:17379480)
PMID:21873635

PMID:17379480 PMID:21873635

MGI:3843426, RGD:13792537

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Kit

KIT proto-oncogene receptor tyrosine kinase

acts_upstream_of_or_within
involved_in

MGI:96974|MGI:97306 (MGI:1351242|PMID:10620616)
PMID:21873635

PMID:10620616 PMID:21873635

MGI:1351242, RGD:13792537

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

Kitlg

KIT ligand

acts_upstream_of_or_within

MGI:96677|MGI:97306 (MGI:1351242|PMID:10620616)

PMID:10620616

MGI:1351242

NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214

Kras

KRAS proto-oncogene, GTPase

RGD

PMID:10969813

RGD:1600497

NCBI chr 4:178,185,418...178,218,484

Lrrk2

leucine-rich repeat kinase 2

involved_in

(PMID:21857923)

PMID:21857923

NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703

Maged1

MAGE family member D1

involved_in

(MGI:3848096|PMID:19268530)

PMID:19268530

MGI:3848096

NCBI chr X:59,422,715...59,429,381
Ensembl chr X:59,422,717...59,429,364

Map2k5

mitogen activated protein kinase kinase 5

involved_in

PMID:20551324

BHF-UCL

PMID:20551324

RGD:8553940

NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983

Map2k6

mitogen-activated protein kinase kinase 6

acts_upstream_of_or_within

(MGI:3032469|PMID:14744933)

PMID:14744933

MGI:3032469

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

Map3k1

mitogen-activated protein kinase kinase kinase 1

RGD

PMID:9110999

RGD:2293488

NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463

Mef2c

myocyte enhancer factor 2C

involved_in

PMID:19103177

Alzheimers_University_of_Toronto

PMID:19103177

RGD:8554846

NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880

Mif

macrophage migration inhibitory factor

involved_in

(MGI:4437204|PMID:10364264)

PMID:10364264

MGI:4437204

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

Mst1r

macrophage stimulating 1 receptor

involved_in

(PMID:12676986)

PMID:12676986

NCBI chr 8:108,596,100...108,611,389
Ensembl chr 8:108,597,299...108,612,455

Nek10

NIMA-related kinase 10

involved_in

(PMID:20956560)
PMID:21873635

PMID:20956560 PMID:21873635

NCBI chr15:10,387,063...10,564,177
Ensembl chr15:10,381,140...10,559,722

Nod2

nucleotide-binding oligomerization domain containing 2

involved_in

(MGI:4946442|PMID:21156799)

PMID:21156799

MGI:4946442

NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177

Nox4

NADPH oxidase 4

involved_in

(MGI:5009390|PMID:17942966)

PMID:17942966

MGI:5009390

NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406

Ntf3

neurotrophin 3

acts_upstream_of
involved_in

(PMID:23027130)
GO_REF:0000107

GO_REF:0000107

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

neurotrophic receptor tyrosine kinase 3

acts_upstream_of

(PMID:23027130)

NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286

P2rx7

purinergic receptor P2X 7

acts_upstream_of_or_within

(MGI:3700006|PMID:17306762)

PMID:17306762

MGI:3700006

NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619

Pdcd10

programmed cell death 10

involved_in

ISO
IBA
ISS

(PMID:17360971)
PMID:21873635
GO_REF:0000024

PMID:17360971 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018

Pde5a

phosphodiesterase 5A

involved_in

(MGI:3836877|PMID:19127022)

PMID:19127022

MGI:3836877

NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701

Pdgfa

platelet derived growth factor subunit A

involved_in

IBA
ISS
ISO

PMID:21873635
GO_REF:0000024
(PMID:11788434)

PMID:11788434 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

platelet derived growth factor subunit B

involved_in

ISO
IDA
IEA
IBA

(PMID:11788434), (PMID:16530387), (PMID:17942966), (PMID:9685360)
PMID:19460854
GO_REF:0000107
PMID:21873635

PMID:9685360 PMID:11788434 PMID:16530387 PMID:17942966 PMID:19460854 More...

GO_REF:0000107, RGD:8554838, RGD:13792537

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

Pdgfc

platelet derived growth factor C

involved_in

PMID:21873635

GO_Central

NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433

Pdgfd

platelet derived growth factor D

involved_in

PMID:21873635

GO_Central

NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395

Pdgfrb

platelet derived growth factor receptor beta

involved_in

GO_REF:0000024
(MGI:5009390|PMID:17942966)

PMID:17942966

GO_REF:0000024 MGI:5009390

NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843

Pik3cg

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

involved_in

(PMID:12507995)

PMID:12507995

NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043

Pik3r5

phosphoinositide-3-kinase, regulatory subunit 5

involved_in

(PMID:12507995)
PMID:21873635

PMID:12507995 PMID:21873635

NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374

Pik3r6

phosphoinositide-3-kinase, regulatory subunit 6

involved_in

PMID:21873635
(MGI:4413485|PMID:19906996)

PMID:19906996 PMID:21873635

MGI:4413485, RGD:13792537

NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243

Pla2g1b

phospholipase A2 group IB

acts_upstream_of

(PMID:15528384), (PMID:16005851)

PMID:15528384 PMID:16005851

NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226

Prkcd

protein kinase C, delta

RGD

PMID:16935468

RGD:1642549

NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352

Psen1

presenilin 1

acts_upstream_of_or_within

(MGI:3579196|PMID:15896720)

PMID:15896720

MGI:3579196

NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650

Ptprc

protein tyrosine phosphatase, receptor type, C

acts_upstream_of_or_within

MGI:2181288 (MGI:1095647|PMID:9254656)

PMID:9254656

MGI:1095647

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Rasgrp1

RAS guanyl releasing protein 1

involved_in

(PMID:15899849)

PMID:15899849

NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056

Robo1

roundabout guidance receptor 1

involved_in

(PMID:21385766)
GO_REF:0000107

PMID:21385766

GO_REF:0000107

NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in

PMID:16530387 PMID:11941412

PMID:16530387

UniProt
RGD

RGD:8553998, RGD:150523765

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

Tab1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

RGD

PMID:21607062

RGD:5508182

NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058

Tdgf1

teratocarcinoma-derived growth factor 1

acts_upstream_of_or_within

(PMID:9013573)

PMID:9013573

NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308

Tenm1

teneurin transmembrane protein 1

involved_in

(MGI:5465054|PMID:22698694)

PMID:22698694

MGI:5465054

NCBI chr X:121,400,466...122,289,877
Ensembl chr X:121,403,649...122,290,207

Tgfa

transforming growth factor alpha

acts_upstream_of

(PMID:11278323)
GO_REF:0000024

RGD
HGNC-UCL

PMID:11278323

GO_REF:0000024

NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894

transforming growth factor, beta 1

involved_in

GO_REF:0000024
(PMID:18625725)

PMID:18625725

GO_REF:0000024

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Thbs1

thrombospondin 1

acts_upstream_of

(PMID:17413041)

PMID:17413041

NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440

Tlr4

toll-like receptor 4

acts_upstream_of
involved_in

(MGI:4421230|PMID:20051628)
GO_REF:0000107

PMID:20051628

GO_REF:0000107 MGI:4421230

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

tumor necrosis factor

involved_in
acts_upstream_of

(PMID:12813029), (PMID:17389591), (PMID:18440775)
(PMID:10748004)

PMID:10748004 PMID:12813029 PMID:17389591 PMID:18440775

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tnfsf11

TNF superfamily member 11

involved_in

(PMID:15304486)
GO_REF:0000107

PMID:15304486

GO_REF:0000107

NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445

Tpd52l1

TPD52 like 1

involved_in

PMID:21873635
(PMID:14761963)

PMID:14761963 PMID:21873635

NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109

vascular endothelial growth factor A

involved_in

(PMID:18440775)
GO_REF:0000107

PMID:18440775

GO_REF:0000107

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

positive regulation of myosin light chain kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fermt2

FERM domain containing kindlin 2

involved_in

(PMID:29496737)

PMID:29496737

NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811

Il1b

interleukin 1 beta

involved_in

(PMID:18390750)

PMID:18390750

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

positive regulation of myosin-light-chain-phosphatase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ppp1r12a

protein phosphatase 1, regulatory subunit 12A

involved_in

(PMID:25816133)
PMID:21873635

PMID:25816133 PMID:21873635

NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425

positive regulation of non-membrane spanning protein tyrosine kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adra1a

adrenoceptor alpha 1A

acts_upstream_of_or_within

(MGI:5888970|PMID:27994061)

PMID:27994061

MGI:5888970

NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500

positive regulation of pathway-restricted SMAD protein phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Acvr1

activin A receptor type 1

involved_in

(PMID:19506109)
(MGI:3610266|PMID:16140292)

PMID:16140292 PMID:19506109

MGI:3610266

NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241

Acvr1b

activin A receptor type 1B

RGD

PMID:17040568

RGD:2315948

NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673

Acvr2a

activin A receptor type 2A

involved_in

GO_REF:0000107
(PMID:19366699)

PMID:19366699

GO_REF:0000107

NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968

Acvrl1

activin A receptor like type 1

involved_in

(PMID:19366699)

PMID:19366699

NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591

Bmp10

bone morphogenetic protein 10

involved_in

IEA
IBA
ISO

GO_REF:0000107
PMID:21873635
(MGI:3695247|PMID:16798733)
(PMID:16049014), (PMID:17068149), (PMID:19903896)

PMID:16049014 PMID:16798733 PMID:17068149 PMID:19903896 PMID:21873635

GO_REF:0000107 MGI:3695247, RGD:13792537

NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627

Bmp15

bone morphogenetic protein 15

involved_in

PMID:21873635

GO_Central

NCBI chr X:16,169,123...16,174,187
Ensembl chr X:16,169,123...16,174,187

Bmp2

bone morphogenetic protein 2

involved_in

ISO
IBA
ISS

(PMID:16049014), (PMID:17244894), (PMID:17992660), (PMID:19664780)
PMID:21873635
GO_REF:0000024

PMID:16049014 PMID:17244894 PMID:17992660 PMID:19664780 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

Bmp3

bone morphogenetic protein 3

involved_in

PMID:21873635

GO_Central

NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153

Bmp4

bone morphogenetic protein 4

involved_in

IEA
IBA
ISS
ISO

GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:16816361), (PMID:17244894), (PMID:17992660), (PMID:20559569), (PMID:9389648)

Ensembl
UniProt
RGD

PMID:9389648 PMID:16816361 PMID:17244894 PMID:17992660 PMID:20559569 More...

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

Bmp5

bone morphogenetic protein 5

involved_in

(PMID:11580864)
PMID:21873635

PMID:11580864 PMID:21873635

NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925

Bmp6

bone morphogenetic protein 6

involved_in

ISO
IBA
ISS

(PMID:17244894), (PMID:19366699)
PMID:21873635
(MGI:4352622|PMID:19252488)
GO_REF:0000024

PMID:17244894 PMID:19252488 PMID:19366699 PMID:21873635

GO_REF:0000024 MGI:4352622, RGD:13792537

NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365

Bmp7

bone morphogenetic protein 7

involved_in

(PMID:16049014), (PMID:17244894), (PMID:19736306), (PMID:9311995)
PMID:21873635

PMID:9311995 PMID:16049014 PMID:17244894 PMID:19736306 PMID:21873635

NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788

Bmp8a

bone morphogenetic protein 8a

involved_in

PMID:21873635

GO_Central

NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785

Bmp8b

bone morphogenetic protein 8b

involved_in

PMID:21873635

GO_Central

NCBI chr 5:135,386,058...135,411,337
Ensembl chr 5:135,386,311...135,405,197

Bmpr1a

bone morphogenetic protein receptor type 1A

involved_in

(PMID:24904118), (PMID:9389648)

PMID:9389648 PMID:24904118

NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616

Bmpr2

bone morphogenetic protein receptor type 2

involved_in

(PMID:17992660), (PMID:19366699)

PMID:17992660 PMID:19366699

NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809

Csnk2b

casein kinase 2 beta

involved_in

(PMID:19592636)
GO_REF:0000107

PMID:19592636

GO_REF:0000107

NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133

Dab2

DAB adaptor protein 2

involved_in

GO_REF:0000107
(PMID:11387212)
(MGI:5317100|PMID:20881059)

PMID:11387212 PMID:20881059

GO_REF:0000107 MGI:5317100

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

Eng

endoglin

involved_in

(PMID:12015308)
(PMID:18974388)

PMID:12015308 PMID:18974388

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

Gdf1

growth differentiation factor 1

involved_in

PMID:21873635

GO_Central

PMID:21712809 PMID:21873635

NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519

Gdf10

growth differentiation factor 10

involved_in

ISS
IBA
ISO
IEA

GO_REF:0000024
PMID:21873635
(MGI:5545973|PMID:21712809)
GO_REF:0000107

UniProt
RGD
Ensembl

GO_REF:0000024 GO_REF:0000107 MGI:5545973, RGD:13792537

NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343

Gdf11

growth differentiation factor 11

involved_in

PMID:21873635

GO_Central

NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725

Gdf15

growth differentiation factor 15

involved_in

PMID:21873635

GO_Central

NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055

Gdf2

growth differentiation factor 2

involved_in

(PMID:17068149), (PMID:19366699), (PMID:19903896)
PMID:21873635

PMID:17068149 PMID:19366699 PMID:19903896 PMID:21873635

NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429

Gdf3

growth differentiation factor 3

involved_in

PMID:21873635

GO_Central

NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937

Gdf5

growth differentiation factor 5

involved_in

PMID:21873635

GO_Central

NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612

Gdf6

growth differentiation factor 6

involved_in

(PMID:16049014)
PMID:21873635

PMID:16049014 PMID:21873635

NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567

Gdf7

growth differentiation factor 7

involved_in

(PMID:16049014)
PMID:21873635

PMID:16049014 PMID:21873635

NCBI chr 6:31,171,495...31,182,447
Ensembl chr 6:31,178,119...31,182,447

Gdf9

growth differentiation factor 9

involved_in

PMID:21873635

GO_Central

NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672

Hfe

homeostatic iron regulator

involved_in

(PMID:24904118)

PMID:24904118

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

Inha

inhibin subunit alpha

involved_in

PMID:21873635

GO_Central

NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248

Inhba

inhibin subunit beta A

involved_in

(PMID:19736306)
PMID:21873635

PMID:19736306 PMID:21873635

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

Inhbb

inhibin subunit beta B

involved_in

PMID:21873635

GO_Central

NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832

Inhbc

inhibin subunit beta C

involved_in

PMID:21873635

GO_Central

NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630

Inhbe

inhibin subunit beta E

involved_in

PMID:21873635

GO_Central

NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172

Lefty1

left right determination factor 1

involved_in

PMID:21873635

GO_Central

NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720

Lefty2

Left-right determination factor 2

involved_in

PMID:21873635

GO_Central

NCBI chr13:92,610,185...92,620,918
Ensembl chr13:92,615,360...92,619,880

Lgals9

galectin 9

involved_in

(MGI:5688819|PMID:25065622)

PMID:25065622

MGI:5688819

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

Mstn

myostatin

involved_in

PMID:21873635

GO_Central

NCBI chr 9:48,453,982...48,458,809
Ensembl chr 9:48,452,533...48,458,933

Nodal

nodal growth differentiation factor

involved_in

(PMID:21741376)
PMID:21873635

PMID:21741376 PMID:21873635

NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837

Pparg

peroxisome proliferator-activated receptor gamma

involved_in

UniProtKB:P01137 (PMID:31023188)
UniProtKB:Q91ZX7 (MGI:6434720|PMID:31023188)

PMID:31023188

MGI:6434720

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

Rbpms

RNA binding protein, mRNA processing factor

involved_in

(PMID:17099224)

PMID:17099224

NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426

Sdcbp

syndecan binding protein

involved_in

IBA
ISS
ISO

PMID:21873635
GO_REF:0000024
(PMID:25893292)

PMID:25893292 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572

Smad4

SMAD family member 4

involved_in

GO_REF:0000107
(MGI:2683382|PMID:14691138)

PMID:14691138

GO_REF:0000107 MGI:2683382

NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438

transforming growth factor, beta 1

involved_in

ISS
IBA
ISO

GO_REF:0000024
PMID:21873635
(PMID:12065756)
(PMID:19736306), (PMID:26634652), (PMID:28467929), (PMID:31023188), (PMID:9389648)

PMID:9389648 PMID:12065756 PMID:19736306 PMID:26634652 PMID:28467929 More...

GO_REF:0000024, RGD:13792537

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Tgfb2

transforming growth factor, beta 2

involved_in

(PMID:18358889)
PMID:21873635

PMID:18358889 PMID:21873635

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

Tgfb3

transforming growth factor, beta 3

involved_in

(MGI:2683382|PMID:14691138)
PMID:21873635

PMID:14691138 PMID:21873635

MGI:2683382, RGD:13792537

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

Tgfbr1

transforming growth factor, beta receptor 1

involved_in

(PMID:12065756), (PMID:9311995), (PMID:9389648)

PMID:9311995 PMID:9389648 PMID:12065756

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

Tgfbr2

transforming growth factor, beta receptor 2

involved_in

(PMID:12065756)

PMID:12065756

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

Twsg1

twisted gastrulation BMP signaling modulator 1

involved_in

(PMID:17164348)

PMID:17164348

NCBI chr 9:105,533,116...105,567,525
Ensembl chr 9:105,533,136...105,567,479

positive regulation of pentose-phosphate shunt

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tigar

TP53 induced glycolysis regulatory phosphatase

involved_in

(MGI:5574521|PMID:24872551)

PMID:24872551

MGI:5574521

NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029

positive regulation of peptidyl-serine dephosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ppp1r15a

protein phosphatase 1, regulatory subunit 15A

involved_in

(PMID:11564868), (PMID:12556489), (PMID:21518769)
(MGI:5605960|PMID:11381086)

PMID:11381086 PMID:11564868 PMID:12556489 PMID:21518769

MGI:5605960

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

positive regulation of peptidyl-serine phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Agt

angiotensinogen

acts_upstream_of_or_within

(MGI:5538470|PMID:23775122)

PMID:23775122

MGI:5538470

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

Akap9

A-kinase anchoring protein 9

involved_in

(PMID:18093912)
PMID:21873635

PMID:18093912 PMID:21873635

NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606

Akt1

AKT serine/threonine kinase 1

involved_in

(PMID:19667065)

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Akt2

AKT serine/threonine kinase 2

RGD

PMID:18348079

RGD:2313324

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

Angpt1

angiopoietin 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:3848848|PMID:19409199)

PMID:19409199

GO_REF:0000107 MGI:3848848

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

App

amyloid beta precursor protein

involved_in

(PMID:19660551)

PMID:19660551

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

Araf

A-Raf proto-oncogene, serine/threonine kinase

involved_in

(PMID:19667065)

NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073

Arrb1

arrestin, beta 1

involved_in

(MGI:4453294|PMID:19915011)

PMID:19915011

MGI:4453294

NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061

arrestin, beta 2

RGD

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

Atp2b4

ATPase plasma membrane Ca2+ transporting 4

involved_in

(PMID:19278978)

PMID:19278978

NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246

Avp

arginine vasopressin

involved_in

(PMID:18402937)

PMID:18402937

NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425

axin 1

involved_in

(MGI:5705228|PMID:11955436)

PMID:11955436

MGI:5705228

NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615

Bag4

BAG cochaperone 4

involved_in

(MGI:5292318|PMID:21712384)

PMID:21712384

MGI:5292318

NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663

Bcar3

BCAR3 adaptor protein, NSP family member

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:4359826 (MGI:4358852|PMID:19365570)

PMID:19365570 PMID:21873635

MGI:4358852, RGD:13792537

NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798

Bcl2

BCL2, apoptosis regulator

acts_upstream_of_or_within

MGI:1097161|MGI:99702 (MGI:3527292|PMID:15613488)

PMID:15613488

MGI:3527292

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

Bdnf

brain-derived neurotrophic factor

acts_upstream_of_or_within
involved_in

IGI
ISO
IBA

PMID:23878391
(MGI:5543306|PMID:23878391)
PMID:21873635

PMID:23878391 PMID:23878391 PMID:21873635

MGI:5543306, RGD:10047172, RGD:13792537

NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615

Braf

B-Raf proto-oncogene, serine/threonine kinase

involved_in

(PMID:19667065)

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

Calcr

calcitonin receptor

involved_in

ComplexPortal:CPX-1134|UniProtKB:O60896|UniProtKB:P10997:PRO_0000004106 (PMID:22500019)

PMID:22500019

NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392

Caprin2

caprin family member 2

involved_in

(PMID:18762581)

PMID:18762581

NCBI chr 4:181,806,105...181,860,754
Ensembl chr 4:181,806,575...181,860,830

Cav1

caveolin 1

involved_in

(PMID:18081315)

PMID:18081315

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

Cd44

CD44 molecule (Indian blood group)

involved_in

(PMID:17045821)
(MGI:3690285|PMID:17045821)

PMID:17045821

MGI:3690285

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

Chek1_v2

checkpoint kinase 1, variant 2

UV-induced

RGD

PMID:11687578

RGD:70230

Chrna7

cholinergic receptor nicotinic alpha 7 subunit

involved_in

GO_REF:0000107
(MGI:3843740|PMID:19230830)

PMID:19230830

GO_REF:0000107 MGI:3843740

NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240

Cnot9

CCR4-NOT transcription complex subunit 9

involved_in

(PMID:20878056)

PMID:20878056

NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100

Crebl2

cAMP responsive element binding protein-like 2

involved_in

GO_REF:0000024
(MGI:5306541|PMID:21728997)

PMID:21728997

GO_REF:0000024 MGI:5306541

NCBI chr 4:167,673,359...167,699,299
Ensembl chr 4:167,673,315...167,699,292

Csf3

colony stimulating factor 3

involved_in

(PMID:23001182)

PMID:23001182

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

Dock7

dedicator of cytokinesis 7

involved_in

(PMID:16982419)

PMID:16982419

NCBI chr 5:113,599,371...113,782,871
Ensembl chr 5:113,600,198...113,782,813

epidermal growth factor receptor

involved_in

(PMID:20878056)

PMID:20878056

NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382

Eif4g1

eukaryotic translation initiation factor 4 gamma 1

involved_in

(PMID:18426977)

PMID:18426977

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

Fnip1

folliculin interacting protein 1

involved_in

(PMID:19914239)

PMID:19914239

NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824

Fnip2

folliculin interacting protein 2

involved_in

(PMID:19914239)
GO_REF:0000024

PMID:19914239

GO_REF:0000024

NCBI chr 2:164,596,557...164,708,147
Ensembl chr 2:164,598,906...164,707,901

Gas6

growth arrest specific 6

involved_in

(PMID:16723520)
GO_REF:0000024

PMID:16723520

GO_REF:0000024

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

Gcg

glucagon

involved_in

GO_REF:0000107
(MGI:4453294|PMID:19915011)

PMID:19915011

GO_REF:0000107 MGI:4453294

NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929

Gsk3a

glycogen synthase kinase 3 alpha

acts_upstream_of_or_within

(MGI:3793516|PMID:17986005)

NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802

Hax1

HCLS1 associated protein X-1

involved_in

(PMID:23001182)

PMID:23001182

NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714

Hcls1

hematopoietic cell specific Lyn substrate 1

involved_in

(PMID:23001182)

PMID:23001182

NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014

Hdac6

histone deacetylase 6

involved_in

(PMID:23962722)
(MGI:6114855|PMID:23962722)

PMID:23962722

MGI:6114855

NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441

Hsp90aa1

heat shock protein 90 alpha family class A member 1

involved_in

(MGI:6148478|PMID:24286867)

PMID:24286867

MGI:6148478

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

Hsp90ab1

heat shock protein 90 alpha family class B member 1

involved_in

(MGI:6148478|PMID:24286867)

PMID:24286867

MGI:6148478

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

Iapp

islet amyloid polypeptide

involved_in

ComplexPortal:CPX-3187|UniProtKB:O60896|UniProtKB:P30988 (PMID:22500019)

PMID:22500019

NCBI chr 4:175,237,013...175,244,373
Ensembl chr 4:175,237,115...175,242,920

Il11

interleukin 11

acts_upstream_of_or_within
involved_in

(PMID:7508917)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

Il6

interleukin 6

acts_upstream_of_or_within

(PMID:7508917)

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Ip6k2

inositol hexakisphosphate kinase 2

acts_upstream_of_or_within

MGI:5635272 (MGI:5581560|PMID:24657168)

PMID:24657168

MGI:5581560

NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166

Irgm

immunity-related GTPase M

involved_in

(PMID:25891078)

PMID:25891078

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

ISL LIM homeobox 1

RGD

NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584

Lats1

large tumor suppressor kinase 1

involved_in

(PMID:20412773)

PMID:20412773

NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640

Lif

LIF, interleukin 6 family cytokine

acts_upstream_of_or_within

(PMID:7508917)

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

Mad2l2

mitotic arrest deficient 2 like 2

involved_in

GO_REF:0000024
(PMID:17296730)

PMID:17296730

GO_REF:0000024

NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693

Mapkap1

MAPK associated protein 1

involved_in

(MGI:3759333|PMID:16962653)

PMID:16962653

MGI:3759333

NCBI chr 3:17,715,813...17,918,387
Ensembl chr 3:17,715,834...17,918,384

Met

MET proto-oncogene, receptor tyrosine kinase

GSK-3beta

RGD

PMID:18262389

RGD:2317458

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

Mif

macrophage migration inhibitory factor

involved_in

(PMID:17045821)
(MGI:3690285|PMID:17045821)

PMID:17045821

MGI:3690285

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

Mtcp1

mature T-cell proliferation 1

involved_in

(PMID:10983986)

PMID:10983986

NCBI chr18:126,189...130,123

Ngf

nerve growth factor

involved_in

PMID:21873635

GO_Central

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

Nos1

nitric oxide synthase 1

involved_in

(PMID:28089352)
GO_REF:0000107

PMID:28089352

GO_REF:0000107

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

Nrxn1

neurexin 1

involved_in

(PMID:26078884)

PMID:26078884

NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710

Ntf3

neurotrophin 3

involved_in

ISO
IBA
IEA

(PMID:23027130)
PMID:21873635
GO_REF:0000107

PMID:23027130 PMID:21873635

GO_REF:0000107, RGD:13792537

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

Ntf4

neurotrophin 4

involved_in

PMID:21873635

GO_Central

NCBI chr 1:95,893,560...95,896,391
Ensembl chr 1:95,893,457...95,897,243

Ntrk2

neurotrophic receptor tyrosine kinase 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5543306|PMID:23878391)

PMID:23878391

GO_REF:0000107 MGI:5543306

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

neurotrophic receptor tyrosine kinase 3

involved_in

(PMID:23027130)

NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286

Oprd1

opioid receptor, delta 1

involved_in

(PMID:24613828)

PMID:24613828

NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960

Osm

oncostatin M

acts_upstream_of_or_within

(PMID:7508917)

NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313

Pak1

p21 (RAC1) activated kinase 1

involved_in

IMP
ISO
ISS

(PMID:19667065)
GO_REF:0000024

PMID:19667065 PMID:23453953

GO_REF:0000024, RGD:10054078

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

Park7

Parkinsonism associated deglycase

involved_in

(PMID:22492997)

PMID:22492997

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

Pdcd10

programmed cell death 10

involved_in

(PMID:20332113)

PMID:20332113

NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018

Pfn2

profilin 2

involved_in

(PMID:23153535)
GO_REF:0000107
(MGI:5545940|PMID:23153535)

PMID:23153535

GO_REF:0000107 MGI:5545940

NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938

Phip

pleckstrin homology domain interacting protein

acts_upstream_of_or_within

(MGI:3723572|PMID:17636024)

PMID:17636024

MGI:3723572

NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283

Pik3ca

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

involved_in

(MGI:5009774|PMID:21047779)

PMID:21047779

MGI:5009774

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

Pink1

PTEN induced kinase 1

involved_in

(PMID:21177249), (PMID:24660806)

PMID:21177249 PMID:24660806

NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635

Ppp1r15a

protein phosphatase 1, regulatory subunit 15A

involved_in

(MGI:5751679|PMID:14635196)

PMID:14635196

MGI:5751679

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

Prkd1

protein kinase D1

involved_in

ISO
IMP

UniProtKB:Q9BZL6 (PMID:20497126)

PMID:20497126 PMID:21041300

RGD:243065274

NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042

Prkd2

protein kinase D2

involved_in

UniProtKB:Q15139 (PMID:20497126)

PMID:20497126

NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376

Ptger2

prostaglandin E receptor 2

involved_in

(PMID:21716255)

PMID:21716255

NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714

Ptgs2

prostaglandin-endoperoxide synthase 2

involved_in

(PMID:21716255)
(MGI:5474549|PMID:21716255)

PMID:21716255

MGI:5474549

NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188

Raf1

Raf-1 proto-oncogene, serine/threonine kinase

involved_in

(PMID:19667065)

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

Ramp3

receptor activity modifying protein 3

involved_in

ComplexPortal:CPX-1134|UniProtKB:P10997:PRO_0000004106|UniProtKB:P30988 (PMID:22500019)

PMID:22500019

NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902

Ripk2

receptor-interacting serine-threonine kinase 2

involved_in

(PMID:21887730)

PMID:21887730

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

Rptor

regulatory associated protein of MTOR, complex 1

involved_in

(PMID:18426977)

PMID:18426977

NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983

Sfrp2

secreted frizzled-related protein 2

involved_in

(MGI:4837797|PMID:20723538)

PMID:20723538

MGI:4837797

NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063

Sh2d3c

SH2 domain containing 3C

involved_in

PMID:21873635

GO_Central

NCBI chr 3:16,010,622...16,046,491
Ensembl chr 3:16,010,625...16,046,484

Smyd3

SET and MYND domain containing 3

acts_upstream_of_or_within

(MGI:5500979|PMID:23752591)

PMID:23752591

MGI:5500979

NCBI chr13:90,709,263...91,266,209
Ensembl chr13:90,709,270...91,266,253

Snca

synuclein alpha

involved_in

(MGI:4936786|PMID:21127069)

PMID:21127069

MGI:4936786

NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262

Spry2

sprouty RTK signaling antagonist 2

involved_in

(PMID:18070883)

PMID:18070883

NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009

Stk4

serine/threonine kinase 4

acts_upstream_of_or_within

(PMID:19962960)

PMID:19962960

NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744

Stox1

storkhead box 1

involved_in

(PMID:22995177)

PMID:22995177

NCBI chr20:30,598,656...30,666,371
Ensembl chr20:30,598,168...30,666,939

Tcl1a

Tcl1 family Akt coactivator A

involved_in

PMID:21873635
(PMID:10983986)

PMID:10983986 PMID:21873635

NCBI chr 6:124,125,032...124,131,025
Ensembl chr 6:124,125,032...124,131,025

Tek

TEK receptor tyrosine kinase

acts_upstream_of_or_within

MGI:108448 (MGI:3848848|PMID:19409199)

PMID:19409199

MGI:3848848

NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804

Tenm1

teneurin transmembrane protein 1

involved_in

(MGI:5465054|PMID:22698694)

PMID:22698694

MGI:5465054

NCBI chr X:121,400,466...122,289,877
Ensembl chr X:121,403,649...122,290,207

Tfrc

transferrin receptor

involved_in

UniProtKB:Q04206 (PMID:23016877)

PMID:23016877

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

transforming growth factor, beta 1

involved_in

(PMID:18625725), (PMID:19736306)
GO_REF:0000024

PMID:18625725 PMID:19736306

GO_REF:0000024

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

tumor necrosis factor

involved_in

ISO
IDA

(PMID:17389591), (PMID:18440775)
PMID:29702085

PMID:17389591 PMID:18440775 PMID:29702085

RGD:13800534

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tnks1bp1

tankyrase 1 binding protein 1

involved_in

(PMID:25749521)

PMID:25749521

NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038

Trim6

tripartite motif containing 6

involved_in

(PMID:24882218)

PMID:24882218

NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914

Txn1

thioredoxin 1

involved_in

GO_REF:0000107
UniProtKB:Q99497 (PMID:22492997)

PMID:22492997

GO_REF:0000107

NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629

Ucn

urocortin

Gsk3b

RGD

PMID:19875195

RGD:5508309

NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950

vascular endothelial growth factor A

involved_in

(PMID:18440775), (PMID:20497126)
GO_REF:0000107

PMID:18440775 PMID:20497126

GO_REF:0000107

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

Wnt3a

Wnt family member 3A

involved_in

(PMID:20723538)

PMID:20723538

NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324

Wnt family member 5A

acts_upstream_of_or_within

MGI:1861437|MGI:2152453 (MGI:3793516|PMID:17986005)

NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234

positive regulation of peptidyl-serine phosphorylation of STAT protein

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ercc6

ERCC excision repair 6, chromatin remodeling factor

involved_in

(PMID:22483866)

PMID:22483866

NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587

Gfra2

GDNF family receptor alpha 2

acts_upstream_of_or_within

(MGI:5529585|PMID:23872421)

PMID:23872421

MGI:5529585

NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714

Ifna4

interferon, alpha 4

involved_in

PMID:21873635

GO_Central

NCBI chr 5:103,069,483...103,070,052
Ensembl chr 5:103,069,483...103,070,052

Ifna5

interferon, alpha 5

involved_in

PMID:21873635

GO_Central

NCBI chr 5:103,187,852...103,188,430

Ifnb1

interferon beta 1

involved_in

(PMID:18035482)
PMID:21873635

PMID:18035482 PMID:21873635

NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523

Ifne

interferon, epsilon

involved_in

PMID:21873635

GO_Central

NCBI chr 5:103,538,001...103,627,561
Ensembl chr 5:103,569,675...103,572,256

Ifng

interferon gamma

involved_in
acts_upstream_of_or_within

IDA
ISO

PMID:20624457
(PMID:16280321)

PMID:16280321 PMID:20624457

RGD:8554478

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Ifnk

interferon kappa

involved_in

PMID:21873635

GO_Central

NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281

Lif

LIF, interleukin 6 family cytokine

involved_in

GO_REF:0000107
(PMID:20624457)

PMID:20624457

GO_REF:0000107

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

LOC120103163

interferon alpha-12-like

involved_in

PMID:21873635

GO_Central

NCBI chr 5:103,494,442...103,495,077
Ensembl chr 5:103,494,448...103,495,002

LOC120103164

interferon alpha-12-like

involved_in

PMID:21873635

GO_Central

NCBI chr 5:103,509,610...103,510,260
Ensembl chr 5:103,509,616...103,510,170

Ret

ret proto-oncogene

acts_upstream_of_or_within

(MGI:5529585|PMID:23872421)

PMID:23872421

MGI:5529585

NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176

RGD1560539

similar to interferon alpha 8/6 precursor; IFNa8/6 (B6)

involved_in

PMID:21873635

GO_Central

NCBI chr 5:103,476,362...103,477,211
Ensembl chr 5:103,476,657...103,477,211

positive regulation of peptidyl-threonine phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenylate cyclase 10

RGD

NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951

App

amyloid beta precursor protein

involved_in

(PMID:19660551)

PMID:19660551

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

axin 1

involved_in

(MGI:5705228|PMID:11955436)

PMID:11955436

MGI:5705228

NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615

Bmp7

bone morphogenetic protein 7

involved_in

(PMID:19736306)

PMID:19736306

NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788

Cab39

calcium binding protein 39

involved_in

(PMID:24393035)

PMID:24393035

NCBI chr 9:86,463,008...86,524,545
Ensembl chr 9:86,463,095...86,524,544

Cemip

cell migration inducing hyaluronidase 1

involved_in

(PMID:23990668)
GO_REF:0000024

PMID:23990668

GO_REF:0000024

NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415

Chi3l1

chitinase 3 like 1

involved_in

GO_REF:0000024
(MGI:5306542|PMID:21546314)

PMID:21546314

GO_REF:0000024 MGI:5306542

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

Egf

epidermal growth factor

involved_in

(PMID:16314496)
GO_REF:0000107

PMID:16314496

GO_REF:0000107

NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064

Gcg

glucagon

involved_in

GO_REF:0000107
(MGI:4453294|PMID:19915011)

PMID:19915011

GO_REF:0000107 MGI:4453294

NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929

Gsk3a

glycogen synthase kinase 3 alpha

acts_upstream_of_or_within

(MGI:3793516|PMID:17986005)

NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802

Gsk3b

glycogen synthase kinase 3 beta

acts_upstream_of_or_within

(MGI:3793516|PMID:17986005)

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

Irgm

immunity-related GTPase M

involved_in

(PMID:25891078)

PMID:25891078

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

Mapk1

mitogen activated protein kinase 1

involved_in

(PMID:16314496)

PMID:16314496

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

Met

MET proto-oncogene, receptor tyrosine kinase

Akt

RGD

PMID:18262389

RGD:2317458

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

Phip

pleckstrin homology domain interacting protein

acts_upstream_of_or_within

(MGI:3723572|PMID:17636024)

PMID:17636024

MGI:3723572

NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283

Plk1

polo-like kinase 1

involved_in

GO_REF:0000107
(PMID:21041660)

PMID:21041660

GO_REF:0000107

NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400

Prkag2

protein kinase AMP-activated non-catalytic subunit gamma 2

involved_in

(PMID:15877279)

PMID:15877279

NCBI chr 4:10,010,574...10,252,152
Ensembl chr 4:10,010,890...10,252,142

Ripk2

receptor-interacting serine-threonine kinase 2

involved_in

(PMID:21887730)

PMID:21887730

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

Rptor

regulatory associated protein of MTOR, complex 1

involved_in

(PMID:18426977)

PMID:18426977

NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983

S1pr2

sphingosine-1-phosphate receptor 2

involved_in

(PMID:23106337)
(MGI:5470025|PMID:23106337)

PMID:23106337

MGI:5470025

NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574

Sphk1

sphingosine kinase 1

involved_in

(PMID:23106337)
GO_REF:0000107

PMID:23106337

GO_REF:0000107

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

Stox1

storkhead box 1

involved_in

(PMID:22995177)

PMID:22995177

NCBI chr20:30,598,656...30,666,371
Ensembl chr20:30,598,168...30,666,939

transforming growth factor, beta 1

involved_in

GO_REF:0000024
(PMID:18625725), (PMID:19736306)

PMID:18625725 PMID:19736306

GO_REF:0000024

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Tnks1bp1

tankyrase 1 binding protein 1

involved_in

(PMID:25749521)

PMID:25749521

NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038

Trim6

tripartite motif containing 6

involved_in

(PMID:24882218)

PMID:24882218

NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914

Trpc5

transient receptor potential cation channel, subfamily C, member 5

RGD

PMID:22699894

RGD:10044018

NCBI chr X:107,946,163...108,230,978
Ensembl chr X:107,939,131...108,230,991

Trpc6

transient receptor potential cation channel, subfamily C, member 6

RGD

PMID:22699894

RGD:10044018

NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092

Ube2k

ubiquitin-conjugating enzyme E2K

involved_in

(PMID:24882218)

PMID:24882218

NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630

Wnk3

WNK lysine deficient protein kinase 3

involved_in

(PMID:16275913)

PMID:16275913

NCBI chr X:20,156,260...20,299,252
Ensembl chr X:20,157,041...20,296,821

Wnt family member 5A

acts_upstream_of_or_within

MGI:1861437|MGI:2152453 (MGI:3793516|PMID:17986005)

NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234

positive regulation of peptidyl-tyrosine autophosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ace

angiotensin I converting enzyme

involved_in

GO_REF:0000107
(MGI:5607357|PMID:25017399)

PMID:25017399

GO_REF:0000107 MGI:5607357

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

Ctnnd1

catenin delta 1

acts_upstream_of_or_within

MGI:98397 (MGI:3763814|PMID:17344476)

PMID:17344476

MGI:3763814

NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516

Grem1

gremlin 1, DAN family BMP antagonist

involved_in

(MGI:4845816|PMID:20660291)

PMID:20660291

MGI:4845816

NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082

Iqgap1

IQ motif containing GTPase activating protein 1

RGD

PMID:23657573

RGD:11049552

NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755

Nrg1

neuregulin 1

involved_in

(PMID:15219672)

PMID:15219672

NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884

Syk

spleen associated tyrosine kinase

acts_upstream_of_or_within

(MGI:5811934|PMID:27609517)

PMID:27609517

MGI:5811934

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

vascular endothelial growth factor A

involved_in

(PMID:20660291)
GO_REF:0000107

PMID:20660291

GO_REF:0000107

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

positive regulation of peptidyl-tyrosine phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abl1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

(PMID:15657060)

PMID:15657060

NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065

Acvr1

activin A receptor type 1

involved_in

(PMID:26598555)

PMID:26598555

NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241

Adipoq

adiponectin, C1Q and collagen domain containing

RGD

PMID:17823255

RGD:1642827

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

Adnp

activity-dependent neuroprotector homeobox