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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of platelet activation
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Accession:GO:0010544 term browser browse the term
Definition:Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.


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negative regulation of platelet activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E ISO (PMID:8995232) BHF-UCL PMID:8995232 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G C1QTNF1 C1q and TNF related 1 ISO (PMID:16195328) UniProtKB PMID:16195328 NCBI chr17:73,099,560...73,126,304
Ensembl chr17:78,644,531...78,669,386
JBrowse link
G GP5 glycoprotein V platelet ISO (MGI:MGI:1347746|PMID:10557321), (MGI:MGI:2137180|PMID:11435305) MGI PMID:10557321, PMID:11435305 MGI:MGI:1347746, MGI:MGI:2137180 NCBI chr 3:191,691,432...191,696,906
Ensembl chr 3:202,008,334...202,010,005
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO (PMID:8188664) UniProtKB PMID:8188664 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097
JBrowse link
G SERPINE2 serpin family E member 2 ISO (MGI:MGI:4418017|PMID:19855083) MGI PMID:19855083 MGI:MGI:4418017 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:12742000 RGD:10047059 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420
JBrowse link
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 ISO (MGI:MGI:3848389|PMID:19218546)
(PMID:19218546)
MGI PMID:19218546 MGI:MGI:3848389 NCBI chr16:57,857,112...58,011,181
Ensembl chr16:77,291,148...77,445,664
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:6140045 RGD:8548522 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO (MGI:MGI:1202206|PMID:9501222) UniProtKB PMID:9501222 MGI:MGI:1202206 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602
JBrowse link
G C1QTNF1 C1q and TNF related 1 ISO (PMID:16195328) UniProtKB PMID:16195328 NCBI chr17:73,099,560...73,126,304
Ensembl chr17:78,644,531...78,669,386
JBrowse link
G CD9 CD9 molecule ISO (PMID:18541721) UniProtKB PMID:18541721 NCBI chr12:6,327,783...6,366,083
Ensembl chr12:6,245,348...6,283,385
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 ISO (MGI:MGI:3835235|PMID:19008452) UniProtKB PMID:19008452 MGI:MGI:3835235 NCBI chr19:39,395,550...39,417,063 JBrowse link
G FGG fibrinogen gamma chain ISO RGD PMID:22985603 RGD:11352706 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237
JBrowse link
G PRKCD protein kinase C delta ISO (MGI:MGI:3813784|PMID:16940418) UniProtKB PMID:16940418 MGI:MGI:3813784 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO (PMID:16990611) UniProtKB PMID:16990611 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:20303752 RGD:10043327 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063
JBrowse link
G SERPINE2 serpin family E member 2 ISO (MGI:MGI:4418017|PMID:19855083) BHF-UCL PMID:19855083 MGI:MGI:4418017 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040
JBrowse link
G SH2B3 SH2B adaptor protein 3 ISO (MGI:MGI:5905608|PMID:27430239) BHF-UCL PMID:27430239 MGI:MGI:5905608 NCBI chr12:108,977,344...109,024,029 JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B ISO (MGI:MGI:4838721|PMID:20585042) MGI PMID:20585042 MGI:MGI:4838721 NCBI chr11:117,489,411...117,647,719
Ensembl chr11:121,410,545...121,563,133
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12529
    negative regulation of biological process 4849
      negative regulation of cellular process 4413
        negative regulation of cell activation 207
          negative regulation of platelet activation 19
            negative regulation of platelet aggregation + 14
Path 2
Term Annotations click to browse term
  biological_process 12529
    biological regulation 9138
      regulation of biological process 8652
        regulation of response to stimulus 3441
          regulation of response to stress 1285
            regulation of response to wounding 177
              regulation of wound healing 136
                regulation of blood coagulation 73
                  negative regulation of blood coagulation 42
                    negative regulation of platelet activation 19
                      negative regulation of platelet aggregation + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.