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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of platelet activation
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Accession:GO:0010543 term browser browse the term
Definition:Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.



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regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig involved_in IBA
ISO
PMID:21873635
(MGI:87668|PMID:9171347)
RGD PMID:9171347 PMID:21873635 MGI:87668, RGD:13792537 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3789419|PMID:15869579), (MGI:4941083|PMID:21264222)
PMID:21873635
UniProt
RGD
PMID:15869579 PMID:21264222 PMID:21873635 GO_REF:0000024 MGI:3789419 MGI:4941083, RGD:13792537 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in ISS
IBA
GO_REF:0000024
PMID:21873635
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(MGI:87668|PMID:9171347)
UniProt
RGD
PMID:9171347 GO_REF:0000024 MGI:87668 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Tec tec protein tyrosine kinase involved_in IBA
ISO
PMID:21873635
(PMID:9299487), (PMID:9652744)
RGD PMID:9299487 PMID:9652744 PMID:21873635 RGD:13792537 NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557
JBrowse link
G Txk TXK tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448
JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
(PMID:8995232)
Ensembl
RGD
PMID:8995232 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of_or_within ISO MGI:2652408 (MGI:1347746|PMID:10557321), (MGI:2137180|PMID:11435305) RGD PMID:10557321 PMID:11435305 MGI:1347746 MGI:2137180 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
IEA
ISS
(PMID:2538439)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA
(PMID:2538439)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:8188664)
UniProt
Ensembl
RGD
PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO MGI:2387774 (MGI:4418017|PMID:19855083) RGD PMID:19855083 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 acts_upstream_of_or_within ISO (MGI:3848389|PMID:19218546)
(PMID:19218546)
RGD PMID:19218546 MGI:3848389 NCBI chr19:41,686,951...41,840,035
Ensembl chr19:41,688,617...41,839,781
JBrowse link
G Adrb2 adrenoceptor beta 2 IMP RGD PMID:6140045 RGD:8548522 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO
GO_REF:0000024
(MGI:1202206|PMID:9501222)
UniProt
RGD
PMID:9501222 GO_REF:0000024 MGI:1202206 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO
IEA
(PMID:16195328)
GO_REF:0000107
RGD
Ensembl
PMID:16195328 GO_REF:0000107 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
GO_REF:0000024
(PMID:18541721)
UniProt
RGD
PMID:18541721 GO_REF:0000024 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3835235|PMID:19008452)
UniProt
RGD
PMID:19008452 GO_REF:0000024 MGI:3835235 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Fgg fibrinogen gamma chain IDA RGD PMID:22985603 RGD:11352706 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Prkcd protein kinase C, delta involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3813784|PMID:16940418)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:16940418 GO_REF:0000024 GO_REF:0000107 MGI:3813784 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:228,409,883...229,638,794 JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:20303752 RGD:10043327 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:4418017|PMID:19855083)
Ensembl
RGD
PMID:19855083 GO_REF:0000107 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P35951 (MGI:5905608|PMID:27430239)
Ensembl
RGD
PMID:27430239 GO_REF:0000107 MGI:5905608 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (MGI:4838721|PMID:20585042) RGD PMID:20585042 MGI:4838721 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
positive regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak2 Janus kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:31145836)
GO_REF:0000107
RGD
Ensembl
PMID:31145836 GO_REF:0000107 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Pdpn podoplanin IMP RGD PMID:16979138 RGD:2292241 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO
IEA
(PMID:18451993)
GO_REF:0000107
RGD
Ensembl
PMID:18451993 GO_REF:0000107 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plek pleckstrin involved_in ISO (MGI:3844782|PMID:19190246) RGD PMID:19190246 MGI:3844782 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (MGI:3847185|PMID:19246339) RGD PMID:19246339 MGI:3847185 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260
JBrowse link
G Selp selectin P involved_in IEA
ISO
GO_REF:0000107
(MGI:3838274|PMID:16514062)
Ensembl
RGD
PMID:16514062 GO_REF:0000107 MGI:3838274 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3838274|PMID:16514062)
Ensembl
RGD
PMID:16514062 GO_REF:0000107 MGI:3838274 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
positive regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmtn dematin actin binding protein involved_in ISO (MGI:5465511|PMID:23060452) RGD PMID:23060452 MGI:5465511 NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601
JBrowse link
G F11r F11 receptor involved_in ISO (PMID:15344881) RGD PMID:15344881 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
JBrowse link
G Il6 interleukin 6 acts_upstream_of ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor acts_upstream_of ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:31145836)
GO_REF:0000107
RGD
Ensembl
PMID:31145836 GO_REF:0000107 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Pdpn podoplanin involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3722196|PMID:17616532), (MGI:4453945|PMID:20110424)
PMID:21873635
(PMID:17222411), (PMID:17616532), (PMID:18541721), (PMID:20110424)
UniProt
RGD
PMID:17222411 PMID:17616532 PMID:18541721 PMID:20110424 PMID:21873635 GO_REF:0000024 MGI:3722196 MGI:4453945, RGD:13792537 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Cela2a chymotrypsin like elastase 2A involved_in ISO
ISS
(PMID:31358993)
GO_REF:0000024
RGD
UniProt
PMID:31358993 GO_REF:0000024 NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5298337|PMID:20189992)
GO_REF:0000024
RGD
UniProt
PMID:20189992 PMID:21873635 GO_REF:0000024 MGI:5298337, RGD:13792537 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Prkca protein kinase C, alpha involved_in ISO
IEA
ISS
(PMID:12724315)
(MGI:3836381|PMID:19147982)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12724315 PMID:19147982 GO_REF:0000024 GO_REF:0000107 MGI:3836381 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcq protein kinase C, theta involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3851048|PMID:19433059)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19433059 GO_REF:0000024 GO_REF:0000107 MGI:3851048 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:87668|PMID:9171347)
PMID:21873635
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:9171347 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:87668, RGD:13792537 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated involved_in ISO (MGI:5645581|PMID:25947942) RGD PMID:25947942 MGI:5645581 NCBI chr 1:134,223,967...134,247,232
Ensembl chr 1:134,223,949...134,246,970
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cell activation 1205
        regulation of cell activation 748
          regulation of platelet activation 42
            negative regulation of platelet activation + 19
            positive regulation of platelet activation 7
            regulation of platelet aggregation + 27
Path 2
Term Annotations click to browse term
  biological_process 19390
    response to stimulus 10323
      response to stress 4024
        response to wounding 633
          wound healing 440
            blood coagulation 189
              platelet activation 109
                regulation of platelet activation 42
                  negative regulation of platelet activation + 19
                  positive regulation of platelet activation 7
                  regulation of platelet aggregation + 27
paths to the root