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ONTOLOGY REPORT - ANNOTATIONS

Term:retrotransposon silencing
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Accession:GO:0010526 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of retrotransposition. Retrotransposons are a subset of transposable elements that use an RNA intermediate and reverse transcribe themselves into the genome.
Synonyms:exact_synonym: negative regulation of transposition, RNA-mediated
 xref: Wikipedia:Retrotransposon_silencing


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retrotransposon silencing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B involved_in ISO (PMID:16527742) UniProt PMID:16527742 NCBI chr 5:9,098,676...9,115,965
Ensembl chr 5:9,097,719...9,116,369 		JBrowse link
G ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:28,859,140...28,910,927
Ensembl chr18:28,859,112...28,910,934 		JBrowse link
G BTBD18 BTB domain containing 18 involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 (MGI:5882241|PMID:28292424) Ensembl
UniProt		 PMID:28292424 GO_REF:0000107 MGI:5882241 NCBI chr 2:13,217,392...13,227,787
Ensembl chr 2:13,217,759...13,227,516 		JBrowse link
G MOV10 Mov10 RNA helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:107,738,089...107,763,873
Ensembl chr 4:107,738,092...107,763,602 		JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (MGI:6214653|PMID:25247314)
(MGI:6303534|PMID:30853213)		 UniProt PMID:25247314 PMID:30853213 MGI:6214653 MGI:6303534 NCBI chr 2:74,568,539...74,577,774
Ensembl chr 2:74,568,493...74,577,772 		JBrowse link
G SIRT7 sirtuin 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,078,155...1,084,112
Ensembl chr12:1,078,166...1,084,119 		JBrowse link
G TDRD9 tudor domain containing 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27473657) Ensembl
MGI		 PMID:27473657 GO_REF:0000107
G TEX15 testis expressed 15, meiosis and synapsis associated involved_in ISO (MGI:6434559|PMID:32381626) UniProt PMID:32381626 MGI:6434559 NCBI chr15:54,210,139...54,277,609 JBrowse link
G TEX19 testis expressed 19 involved_in ISO (PMID:28806172) UniProt PMID:28806172 NCBI chr12:713,179...715,704 JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:37,655,808...37,785,301
Ensembl chr 7:37,655,926...37,784,359 		JBrowse link
piRNA-mediated retrotransposon silencing by heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX4 DEAD-box helicase 4 acts_upstream_of_positive_effect ISS UniProt GO_REF:0000024 NCBI chr16:34,879,701...34,983,701
Ensembl chr16:34,858,368...34,983,699 		JBrowse link
G PIWIL1 piwi like RNA-mediated gene silencing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:24,729,346...24,760,056
Ensembl chr14:24,729,113...24,760,320 		JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 (MGI:5501381|PMID:23706823) Ensembl
UniProt		 PMID:23706823 GO_REF:0000107 MGI:5501381 NCBI chr14:6,560,402...6,632,524
Ensembl chr14:6,560,565...6,632,523 		JBrowse link
G SPOCD1 SPOC domain containing 1 involved_in ISO (MGI:6453929|PMID:32674113) UniProt PMID:32674113 MGI:6453929 NCBI chr 6:88,323,119...88,349,194
Ensembl chr 6:88,323,080...88,349,963 		JBrowse link
G TDRD9 tudor domain containing 9 involved_in IEA Ensembl GO_REF:0000107
G TEX15 testis expressed 15, meiosis and synapsis associated involved_in ISO (MGI:6447460|PMID:32719317) UniProt PMID:32719317 MGI:6447460 NCBI chr15:54,210,139...54,277,609 JBrowse link
retrotransposon silencing by heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3B DNA methyltransferase 3 beta acts_upstream_of_or_within ISO (PMID:27856912) MGI PMID:27856912 NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072 		JBrowse link
G DNMT3L DNA methyltransferase 3 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25503965) Ensembl
MGI		 PMID:25503965 GO_REF:0000107 NCBI chr13:207,119,025...207,141,990
Ensembl chr13:207,119,051...207,132,538 		JBrowse link
G MORC1 MORC family CW-type zinc finger 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25503965) Ensembl
MGI		 PMID:25503965 GO_REF:0000107 NCBI chr13:150,387,942...150,561,808
Ensembl chr13:150,268,234...150,560,867 		JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 (MGI:5319753|PMID:22020280) Ensembl
UniProt		 PMID:22020280 GO_REF:0000107 MGI:5319753 NCBI chr14:6,560,402...6,632,524
Ensembl chr14:6,560,565...6,632,523 		JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 acts_upstream_of_positive_effect
acts_upstream_of_or_within		 ISO (MGI:5319753|PMID:22020280)
(PMID:25503965)		 UniProt
MGI		 PMID:22020280 PMID:25503965 MGI:5319753 NCBI chr 9:26,679,960...26,751,856
Ensembl chr 9:26,703,340...26,751,854 		JBrowse link
G SMYD5 SMYD family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,552,731...69,566,013
Ensembl chr 3:69,552,738...69,565,978 		JBrowse link
G SMYD5 SMYD family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,566,112...69,571,165
Ensembl chr 3:69,567,449...69,571,100 		JBrowse link
retrotransposon silencing by mRNA destabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MOV10 Mov10 RNA helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:107,738,089...107,763,873
Ensembl chr 4:107,738,092...107,763,602 		JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:6,560,402...6,632,524
Ensembl chr14:6,560,565...6,632,523 		JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 involved_in ISO (MGI:3815367|PMID:18922463) UniProt PMID:18922463 MGI:3815367 NCBI chr 9:26,679,960...26,751,856
Ensembl chr 9:26,703,340...26,751,854 		JBrowse link
G TUT4 terminal uridylyl transferase 4 involved_in ISO (PMID:30122351) UniProt PMID:30122351 NCBI chr 6:159,655,658...159,794,450
Ensembl chr 6:159,692,797...159,793,758 		JBrowse link
G TUT7 terminal uridylyl transferase 7 involved_in ISO (PMID:30122351) UniProt PMID:30122351 NCBI chr10:28,995,564...29,061,179
Ensembl chr10:28,995,565...29,061,176 		JBrowse link
siRNA-mediated retrotransposon silencing by heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX4 DEAD-box helicase 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr16:34,879,701...34,983,701
Ensembl chr16:34,858,368...34,983,699 		JBrowse link
G FKBP6 FKBP prolyl isomerase family member 6 (inactive) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,659,456...10,716,210
Ensembl chr 3:10,669,664...10,682,618 		JBrowse link
G MAEL maelstrom spermatogenic transposon silencer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:83,990,266...84,040,465
Ensembl chr 4:83,990,273...84,040,465 		JBrowse link
G MOV10L1 Mov10 like RNA helicase 1 involved_in ISO (MGI:4457283|PMID:20534472) UniProt PMID:20534472 MGI:4457283 NCBI chr 5:509,868...567,429 JBrowse link
G MYBL1 MYB proto-oncogene like 1 acts_upstream_of_positive_effect ISO (MGI:5495879|PMID:23523368) UniProt PMID:23523368 MGI:5495879 NCBI chr 4:68,120,078...68,159,513
Ensembl chr 4:68,119,865...68,159,509 		JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:6,560,402...6,632,524
Ensembl chr14:6,560,565...6,632,523 		JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 involved_in ISO (MGI:3778312|PMID:18381894) UniProt PMID:18381894 MGI:3778312 NCBI chr 9:26,679,960...26,751,856
Ensembl chr 9:26,703,340...26,751,854 		JBrowse link
G TDRD1 tudor domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:124,526,013...124,575,166
Ensembl chr14:124,529,586...124,573,244 		JBrowse link
G TDRD12 tudor domain containing 12 involved_in ISO (MGI:5516419|PMID:24067652) UniProt PMID:24067652 MGI:5516419 NCBI chr 6:42,589,557...42,667,946
Ensembl chr 6:42,589,556...42,665,845 		JBrowse link
G TDRD5 tudor domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:121,245,080...121,337,339
Ensembl chr 9:121,211,960...121,333,220 		JBrowse link
G TDRD9 tudor domain containing 9 involved_in IEA Ensembl GO_REF:0000107
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17813
    negative regulation of biological process 5569
      negative regulation of cellular process 5222
        retrotransposon silencing 29
          retrotransposon silencing by heterochromatin formation + 19
          retrotransposon silencing by mRNA destabilization + 5
Path 2
Term Annotations click to browse term
  biological_process 17813
    biological regulation 12832
      regulation of biological process 12482
        regulation of cellular process 12025
          negative regulation of cellular process 5222
            retrotransposon silencing 29
              retrotransposon silencing by heterochromatin formation + 19
              retrotransposon silencing by mRNA destabilization + 5
paths to the root