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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cell fate commitment
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Accession:GO:0010455 term browser browse the term
Definition:Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.


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positive regulation of cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx6-2 NK6 homeobox 2 ISO MGI:2651850 (MGI:2150481|PMID:11567614) RGD PMID:11567614 MGI:2150481 NCBI chr 1:211,922,389...211,923,929
Ensembl chr 1:211,922,389...211,923,929
JBrowse link
G Spdef SAM pointed domain containing ets transcription factor ISO MGI:4398888 (MGI:4397649|PMID:19759516) RGD PMID:19759516 MGI:4397649 NCBI chr20:7,292,823...7,308,053
Ensembl chr20:7,292,824...7,307,284
JBrowse link
positive regulation of cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO (PMID:18635606) RGD PMID:18635606 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor ISO MGI:2449921 (MGI:3606816|PMID:16230531) RGD PMID:16230531 MGI:3606816 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
JBrowse link
G Pax6 paired box 6 IMP RGD PMID:11880342 RGD:729590 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23 subunit alpha IBA
ISO
PMID:21873635
(MGI:3851279|PMID:19501566)
RGD PMID:19501566, PMID:21873635 MGI:3851279, RGD:13792537 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      positive regulation of cellular process 6145
        positive regulation of cell differentiation 961
          positive regulation of cell fate commitment 7
            positive regulation of T-helper 17 cell lineage commitment 1
            positive regulation of cell fate specification + 4
            positive regulation of mating type switching 0
            positive regulation of retinal rod cell fate commitment 0
            positive regulation of venous endothelial cell fate commitment 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      cellular developmental process 4457
        cell differentiation 4362
          regulation of cell differentiation 1684
            positive regulation of cell differentiation 961
              positive regulation of cell fate commitment 7
                positive regulation of T-helper 17 cell lineage commitment 1
                positive regulation of cell fate specification + 4
                positive regulation of mating type switching 0
                positive regulation of retinal rod cell fate commitment 0
                positive regulation of venous endothelial cell fate commitment 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.