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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell fate commitment
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Accession:GO:0010454 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.



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negative regulation of cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glis1 GLIS family zinc finger 1 involved_in ISO (MGI:6294234|PMID:30544251) RGD PMID:30544251 MGI:6294234 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141
JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO MGI:109452 (MGI:3654744|PMID:16801560) RGD PMID:16801560 MGI:3654744 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Nkx6-2 NK6 homeobox 2 acts_upstream_of_or_within ISO MGI:2651850 (MGI:2150481|PMID:11567614) RGD PMID:11567614 MGI:2150481 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515
JBrowse link
G Sostdc1 sclerostin domain containing 1 acts_upstream_of_or_within ISO MGI:3604658 (MGI:5319554|PMID:22509524) RGD PMID:22509524 MGI:5319554 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579
JBrowse link
G Spdef SAM pointed domain containing ets transcription factor acts_upstream_of_or_within ISO MGI:4398888 (MGI:4397649|PMID:19759516) RGD PMID:19759516 MGI:4397649 NCBI chr20:5,771,434...5,786,793
Ensembl chr20:5,771,441...5,785,893
JBrowse link
negative regulation of cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2149672 (MGI:2136156|PMID:11425898)
Ensembl
RGD
PMID:11425898 GO_REF:0000107 MGI:2136156 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO MGI:2449921 (MGI:3606816|PMID:16230531) RGD PMID:16230531 MGI:3606816 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:18681827) RGD PMID:18681827 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:98956 (MGI:3711603|PMID:17462603) RGD PMID:17462603 MGI:3711603 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
negative regulation of retinal cone cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 acts_upstream_of_or_within ISO MGI:3052661|MGI:4841554 (MGI:5629913|PMID:25654255) RGD PMID:25654255 MGI:5629913 NCBI chr 5:159,243,965...159,393,935
Ensembl chr 5:159,243,995...159,393,400
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase-like 3 involved_in ISO (MGI:5825383|PMID:28065600) RGD PMID:28065600 MGI:5825383 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) RGD PMID:24107315 MGI:5551556 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      negative regulation of cellular process 5131
        negative regulation of cell differentiation 745
          negative regulation of cell fate commitment 16
            negative regulation of R7 cell fate commitment 0
            negative regulation of T-helper 17 cell lineage commitment 3
            negative regulation of anterior neural cell fate commitment of the neural plate + 0
            negative regulation of cell fate determination + 1
            negative regulation of cell fate specification + 6
            negative regulation of establishment or maintenance of neuroblast polarity 0
            negative regulation of mating type switching 0
            negative regulation of retinal cone cell fate commitment + 1
            negative regulation of sevenless signaling pathway 0
            negative regulation of venous endothelial cell fate commitment + 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      cellular developmental process 4543
        cell differentiation 4448
          regulation of cell differentiation 1719
            negative regulation of cell differentiation 745
              negative regulation of cell fate commitment 16
                negative regulation of R7 cell fate commitment 0
                negative regulation of T-helper 17 cell lineage commitment 3
                negative regulation of anterior neural cell fate commitment of the neural plate + 0
                negative regulation of cell fate determination + 1
                negative regulation of cell fate specification + 6
                negative regulation of establishment or maintenance of neuroblast polarity 0
                negative regulation of mating type switching 0
                negative regulation of retinal cone cell fate commitment + 1
                negative regulation of sevenless signaling pathway 0
                negative regulation of venous endothelial cell fate commitment + 0
paths to the root