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ONTOLOGY REPORT - ANNOTATIONS

Term:polyprenyldihydroxybenzoate methyltransferase activity
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Accession:GO:0010420 term browser browse the term
Definition:Catalysis of the reaction: a 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-methionine = a 3-methoxy,4-hydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-homocysteine + H+.
Comment:Note that the polyprenyl sidechain substrate for this reaction has a different number of prenyl units in different organisms (for example, ubiquinone-6 in Saccharomyces, ubiquinone- 9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units.
Synonyms:exact_synonym: 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity
 alt_id: GO:1990886
 xref: EC:2.1.1.114;   MetaCyc:RXN-9281;   RHEA:44452;   Reactome:R-HSA-2162193 "COQ3 methylates DHDB"


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polyprenyldihydroxybenzoate methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coq3 coenzyme Q3 methyltransferase enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607 		JBrowse link
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  molecular_function 21087
    catalytic activity 6127
      transferase activity 2447
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              polyprenyldihydroxybenzoate methyltransferase activity 1
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