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ONTOLOGY REPORT - ANNOTATIONS


Term:response to ionizing radiation
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Accession:GO:0010212 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
Synonyms:exact_synonym: response to ionising radiation;   response to ionizing radiation stimulus


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response to ionizing radiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 ISO RGD PMID:17132608 RGD:1598660 NCBI chrNW_004936508:8,093,804...8,117,467 JBrowse link
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chrNW_004936738:1,202,668...1,217,825 JBrowse link
G Aen apoptosis enhancing nuclease involved_in ISO (PMID:16171785) UniProt PMID:16171785 NCBI chrNW_004936483:14,601,671...14,611,613 JBrowse link
G Alad aminolevulinate dehydratase ISO 131Iodine RGD PMID:17916974 RGD:4144160 NCBI chrNW_004936559:226,481...237,258 JBrowse link
G Atm ATM serine/threonine kinase involved_in
acts_upstream_of_or_within
ISO (PMID:11375976), (PMID:9733515)
(MGI:1352316|PMID:10639175)
(MGI:3836659|PMID:19061978)
BHF-UCL
MGI
PMID:9733515 PMID:10639175 PMID:11375976 PMID:19061978 MGI:1352316 MGI:3836659 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISO (PMID:19261748), (PMID:19261749) UniProt PMID:19261748 PMID:19261749 NCBI chrNW_004936596:3,574,507...3,582,370 JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISO (PMID:19261748), (PMID:19261749) UniProt PMID:19261748 PMID:19261749 NCBI chrNW_004936493:4,375,393...4,863,050 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:3512739|PMID:15578100)
(MGI:1352316|PMID:10639175)
MGI PMID:10639175 PMID:15578100 MGI:1352316 MGI:3512739 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Brat1 BRCA1 associated ATM activator 1 involved_in ISO (PMID:16452482) UniProt PMID:16452482 NCBI chrNW_004936823:393,878...404,348 JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:17525341), (PMID:19261746), (PMID:19261748) UniProt PMID:17525341 PMID:19261746 PMID:19261748 NCBI chrNW_004936927:341,114...380,817 JBrowse link
G Brsk1 BR serine/threonine kinase 1 NOT|involved_in ISO (PMID:15150265) UniProt PMID:15150265 NCBI chrNW_004936886:541,831...567,197 JBrowse link
G Clk2 CDC like kinase 2 involved_in ISO (PMID:20682768) UniProt PMID:20682768 NCBI chrNW_004936580:4,746,276...4,758,236 JBrowse link
G Cop1 COP1 E3 ubiquitin ligase involved_in ISO (PMID:19805145) UniProt PMID:19805145 NCBI chrNW_004936481:12,262,415...12,437,627 JBrowse link
G CUNH10orf90 chromosome unknown C10orf90 homolog involved_in ISO (MGI:4455105|PMID:20154723) UniProt PMID:20154723 MGI:4455105 NCBI chrNW_004936486:14,311,976...14,499,733 JBrowse link
G Dclre1c DNA cross-link repair 1C acts_upstream_of_or_within ISO (MGI:2447929|PMID:12504013)
(MGI:3514096|PMID:12615897)
MGI PMID:12504013 PMID:12615897 MGI:2447929 MGI:3514096 NCBI chrNW_004936613:1,467,797...1,501,107 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO RGD PMID:17148264 RGD:1601086 NCBI chrNW_004936659:520,181...565,496 JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO RGD PMID:17148264 RGD:1601086 NCBI chrNW_004936493:6,963,406...7,013,256 JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO RGD PMID:17148264 RGD:1601086 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (PMID:19234442) UniProt PMID:19234442 NCBI chrNW_004936648:395,526...546,705 JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in ISO (PMID:19234442) UniProt PMID:19234442 NCBI chrNW_004936474:12,191,391...12,295,380 JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO gamma irradiation RGD PMID:20385203 RGD:4145425 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G Ints3 integrator complex subunit 3 involved_in ISO (PMID:19605351), (PMID:19683501) UniProt PMID:19605351 PMID:19683501 NCBI chrNW_004936580:3,511,364...3,553,441 JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO (PMID:18397884) UniProt PMID:18397884 NCBI chrNW_004936599:3,767,526...3,775,416 JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (MGI:4943978|PMID:21390131)
(MGI:1859491|PMID:10823907)
MGI PMID:10823907 PMID:21390131 MGI:1859491 MGI:4943978 NCBI chrNW_004936472:3,861,833...3,867,943 JBrowse link
G LOC101954950 aromatase ISO enriched uranium RGD PMID:18821396 RGD:4770368 NCBI chrNW_004936471:13,107,603...13,136,910 JBrowse link
G LOC101965648 INTS3 and NABP interacting protein involved_in ISO (PMID:19605351), (PMID:19683501) UniProt PMID:19605351 PMID:19683501 NCBI chrNW_004936559:813,912...830,768 JBrowse link
G LOC101970767 steroid 17-alpha-hydroxylase/17,20 lyase ISO enriched uranium RGD PMID:18821396 RGD:4770368 NCBI chrNW_004936600:3,097,620...3,102,713 JBrowse link
G LOC101972957 vitamin D 25-hydroxylase ISO RGD PMID:16806633 RGD:1601035 NCBI chrNW_004936528:3,881,630...3,897,613 JBrowse link
G LOC101975820 cholesterol side-chain cleavage enzyme, mitochondrial ISO enriched uranium RGD PMID:18821396 RGD:4770368 NCBI chrNW_004936471:33,367,810...33,380,764 JBrowse link
G Lzic leucine zipper and CTNNBIP1 domain containing ISO RGD PMID:19444910 RGD:2314410 NCBI chrNW_004936623:3,851,208...3,862,521 JBrowse link
G Mecp2 methyl-CpG binding protein 2 ISO RGD PMID:17148264 RGD:1601086 NCBI chrNW_004936809:902,938...967,771 JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chrNW_004936739:926,678...955,024 JBrowse link
G Mta1 metastasis associated 1 involved_in ISO (PMID:19805145)
(MGI:4366101|PMID:19805145)
UniProt PMID:19805145 MGI:4366101 NCBI chrNW_004936621:117,785...140,917 JBrowse link
G Nabp1 nucleic acid binding protein 1 involved_in ISO (PMID:19605351), (PMID:19683501) UniProt PMID:19605351 PMID:19683501 NCBI chrNW_004936506:6,608,333...6,616,076 JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISO (PMID:19605351), (PMID:19683501) UniProt PMID:19605351 PMID:19683501 NCBI chrNW_004936646:632,390...638,900 JBrowse link
G Nek1 NIMA related kinase 1 acts_upstream_of_or_within ISO (MGI:3522367|PMID:15604234) MGI PMID:15604234 MGI:3522367 NCBI chrNW_004936516:1,508,800...1,666,841 JBrowse link
G Nes nestin ISO RGD PMID:12445635 RGD:1642076 NCBI chrNW_004936580:5,837,949...5,847,499 JBrowse link
G Nhej1 non-homologous end joining factor 1 involved_in ISO (PMID:16439205) UniProt PMID:16439205 NCBI chrNW_004936569:1,494,783...1,578,587 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:15456759) UniProt PMID:15456759 NCBI chrNW_004936527:9,440,129...9,488,215 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO (MGI:5014034|PMID:20150414) MGI PMID:20150414 MGI:5014034 NCBI chrNW_004936590:4,722,914...4,887,615 JBrowse link
G Rad54b RAD54 homolog B acts_upstream_of_or_within ISO (MGI:3615835|PMID:16428451)
(MGI:3836659|PMID:19061978)
MGI PMID:16428451 PMID:19061978 MGI:3615835 MGI:3836659 NCBI chrNW_004936544:7,375,566...7,475,319 JBrowse link
G Rad54l RAD54 like acts_upstream_of_or_within ISO (MGI:3615835|PMID:16428451), (MGI:5014034|PMID:20150414)
(MGI:3836659|PMID:19061978)
MGI PMID:16428451 PMID:19061978 PMID:20150414 MGI:3615835 MGI:3836659 MGI:5014034 NCBI chrNW_004936474:27,276,570...27,316,427 JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:20173098) UniProt PMID:20173098 NCBI chrNW_004936475:23,544,974...23,586,716 JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (PMID:19203578), (PMID:19203579) UniProt PMID:19203578 PMID:19203579 NCBI chrNW_004936784:1,073,236...1,094,575 JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (PMID:18001824), (PMID:18001825) UniProt PMID:18001824 PMID:18001825 NCBI chrNW_004936476:22,074,146...22,121,286 JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 ISO RGD PMID:19444910 RGD:2314410 NCBI chrNW_004936498:815,401...848,749 JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in ISO (PMID:8706124)
(MGI:82530|PMID:8706124)
UniProt PMID:8706124 MGI:82530 NCBI chrNW_004936842:448,315...452,557 JBrowse link
G Star steroidogenic acute regulatory protein ISO enriched uranium RGD PMID:18821396 RGD:4770368 NCBI chrNW_004936710:1,523,289...1,530,181 JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO (MGI:5284815|PMID:12234250) UniProt PMID:12234250 MGI:5284815 NCBI chrNW_004936588:579,816...601,033 JBrowse link
G Top2a DNA topoisomerase II alpha ISO RGD PMID:22965249 RGD:13432139 NCBI chrNW_004936490:15,441,463...15,465,692 JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in ISO (PMID:12773567) UniProt PMID:12773567 NCBI chrNW_004936529:6,788,713...6,841,824 JBrowse link
G Tp53bp2 tumor protein p53 binding protein 2 acts_upstream_of_or_within ISO (MGI:3624572|PMID:16702401) MGI PMID:16702401 MGI:3624572 NCBI chrNW_004936526:936,981...1,000,070 JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in ISO (PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 NCBI chrNW_004936597:1,143,835...1,260,339 JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISO (PMID:16901786) UniProt PMID:16901786 NCBI chrNW_004936612:742,777...804,919 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO RGD PMID:19714308 RGD:2312872 NCBI chrNW_004936748:785,491...802,791 JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (MGI:3761960|PMID:17713479) MGI PMID:17713479 MGI:3761960 NCBI chrNW_004936469:2,248,367...2,495,215 JBrowse link
G Xrcc6 X-ray repair cross complementing 6 acts_upstream_of_or_within ISO (MGI:3613277|PMID:15979950)
(MGI:5007842|PMID:21568942)
MGI PMID:15979950 PMID:21568942 MGI:3613277 MGI:5007842 NCBI chrNW_004936492:303,843...325,812 JBrowse link
cellular response to gamma radiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:16213212), (PMID:9925639) CAFA PMID:9925639 PMID:16213212 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:9925639) BHF-UCL PMID:9925639 NCBI chrNW_004936540:4,074,543...4,178,859 JBrowse link
G Bcl2l1 BCL2 like 1 acts_upstream_of_or_within ISO (MGI:3057092|PMID:15231831) MGI PMID:15231831 MGI:3057092 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (MGI:1354114|PMID:10710310) MGI PMID:10710310 MGI:1354114 NCBI chrNW_004936476:22,717,308...22,725,127 JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO (MGI:1354114|PMID:10710310) MGI PMID:10710310 MGI:1354114 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G Cryab crystallin alpha B acts_upstream_of_or_within ISO (PMID:23542032) MGI PMID:23542032 NCBI chrNW_004936612:2,532,851...2,536,473 JBrowse link
G Ddias DNA damage induced apoptosis suppressor acts_upstream_of_or_within ISO (MGI:3718924|PMID:17515607) MGI PMID:17515607 MGI:3718924 NCBI chrNW_004936498:11,115,055...11,127,215 JBrowse link
G Egr1 early growth response 1 involved_in ISO (MGI:3830454|PMID:19057511) BHF-UCL PMID:19057511 MGI:3830454 NCBI chrNW_004936531:7,625,956...7,629,041 JBrowse link
G Elk1 ETS transcription factor ELK1 ISO RGD PMID:17949253 RGD:7488908 NCBI chrNW_004936502:13,402,726...13,418,214 JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 acts_upstream_of_or_within ISO (MGI:5506835|PMID:23637614) MGI PMID:23637614 MGI:5506835 NCBI chrNW_004936489:9,983,935...9,993,179 JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:16213212) CAFA PMID:16213212 NCBI chrNW_004936888:375,372...378,125 JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:26359349) UniProt PMID:26359349 NCBI chrNW_004936470:7,927,734...7,950,805 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:20470193 RGD:11354917 NCBI chrNW_004936487:13,348,465...13,352,717 JBrowse link
G Kdm1a lysine demethylase 1A acts_upstream_of_or_within ISO (PMID:24217620) MGI PMID:24217620 NCBI chrNW_004936474:8,262,913...8,319,089 JBrowse link
G LOC101966907 histone H2AX ISO RGD PMID:17552875 RGD:8693710 NCBI chrNW_004936542:4,046,930...4,049,017 JBrowse link
G LOC101967032 cytochrome b-245 light chain ISO RGD PMID:18640264 RGD:2317861 NCBI chrNW_004936641:1,036,967...1,044,954 JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) UniProt PMID:11836244 NCBI chrNW_004936509:3,029,942...3,203,319 JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:16213212) CAFA PMID:16213212 NCBI chrNW_004936545:6,709,903...6,732,334 JBrowse link
G Nox4 NADPH oxidase 4 ISO RGD PMID:18640264 RGD:2317861 NCBI chrNW_004936736:230,465...394,859 JBrowse link
G Rad51 RAD51 recombinase ISO RGD PMID:9885240 RGD:9831175 NCBI chrNW_004936471:4,119,020...4,136,811 JBrowse link
G Rnf4 ring finger protein 4 ISO RGD PMID:22661230 RGD:9480235 NCBI chrNW_004936477:21,025,040...21,055,821 JBrowse link
G Rpl13a ribosomal protein L13a ISO RGD PMID:10483362 RGD:11036101 NCBI chrNW_004936664:3,352,535...3,356,196 JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212) CAFA PMID:16213212 NCBI chrNW_004936595:1,603,913...1,609,125 JBrowse link
G Tlk2 tousled like kinase 2 involved_in ISO (PMID:12660173) UniProt PMID:12660173 NCBI chrNW_004936541:3,303,563...3,422,093 JBrowse link
G Tmem109 transmembrane protein 109 acts_upstream_of_or_within ISO (PMID:23542032) MGI PMID:23542032 NCBI chrNW_004936581:2,009,357...2,019,381 JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:16213212)
(MGI:1354114|PMID:10710310)
CAFA
MGI
PMID:10710310 PMID:16213212 MGI:1354114 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (MGI:3818783|PMID:18045533) MGI PMID:18045533 MGI:3818783 NCBI chrNW_004936529:264,535...266,451 JBrowse link
G Tspyl5 TSPY like 5 involved_in ISO (PMID:20079711) UniProt PMID:20079711 NCBI chrNW_004936470:45,385,155...45,410,307 JBrowse link
G Wrn WRN RecQ like helicase involved_in ISO (PMID:21639834) UniProt PMID:21639834 NCBI chrNW_004936792:862,659...1,005,065 JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:26359349) UniProt PMID:26359349 NCBI chrNW_004936586:1,055,478...1,137,924 JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:26359349) UniProt PMID:26359349 NCBI chrNW_004936492:303,843...325,812 JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in ISO (PMID:18280240) UniProt PMID:18280240 NCBI chrNW_004936551:5,638,383...5,740,523 JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (MGI:3583382|PMID:15980864) MGI PMID:15980864 MGI:3583382 NCBI chrNW_004936474:22,035,059...22,077,846 JBrowse link
cellular response to ionizing radiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbc3 BCL2 binding component 3 acts_upstream_of_or_within ISO (MGI:3690827|PMID:16286009) MGI PMID:16286009 MGI:3690827 NCBI chrNW_004936664:962,115...966,797 JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:23509288) UniProt PMID:23509288 NCBI chrNW_004936483:16,194,092...16,295,803 JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:20160708) BHF-UCL PMID:20160708 NCBI chrNW_004936476:22,717,308...22,725,127 JBrowse link
G Clock clock circadian regulator involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004936482:17,789,834...17,900,371 JBrowse link
G Ect2 epithelial cell transforming 2 involved_in ISO (PMID:21373644) UniProt PMID:21373644 NCBI chrNW_004936703:5,744...45,636 JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta involved_in ISO (PMID:8168075) UniProt PMID:8168075 NCBI chrNW_004936470:8,538,899...8,553,645 JBrowse link
G Fbxo4 F-box protein 4 acts_upstream_of_or_within ISO (MGI:5299398|PMID:21911473) MGI PMID:21911473 MGI:5299398 NCBI chrNW_004936518:855,304...873,927 JBrowse link
G Fignl1 fidgetin like 1 involved_in ISO (PMID:23754376) UniProt PMID:23754376 NCBI chrNW_004936686:1,412,544...1,415,939 JBrowse link
G Gadd45a growth arrest and DNA damage inducible alpha involved_in ISO (PMID:20160708) BHF-UCL PMID:20160708 NCBI chrNW_004936591:3,998,359...4,001,491 JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO (PMID:20160708) BHF-UCL PMID:20160708 NCBI chrNW_004936594:592,760...661,369 JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004936478:22,393,952...22,414,349 JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20687897) UniProt PMID:20687897 NCBI chrNW_004936471:4,374,802...4,478,894 JBrowse link
G Ints7 integrator complex subunit 7 involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004936557:1,389,728...1,456,397 JBrowse link
G Itgb1 integrin subunit beta 1 ISO RGD PMID:19714308 RGD:2312872 NCBI chrNW_004936574:1,465,981...1,495,717 JBrowse link
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within ISO (MGI:3842254|PMID:17916808) MGI PMID:17916808 MGI:3842254 NCBI chrNW_004936469:18,581,855...18,650,109 JBrowse link
G Lig4 DNA ligase 4 involved_in ISO (PMID:29463814) UniProt PMID:29463814 NCBI chrNW_004936472:3,861,833...3,867,943 JBrowse link
G LOC101967900 lysine-specific demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) MGI PMID:24550317 NCBI chrNW_004936674:53,200...73,042 JBrowse link
G Mapk14 mitogen-activated protein kinase 14 involved_in ISO (PMID:20160708) BHF-UCL PMID:20160708 NCBI chrNW_004936476:23,237,762...23,310,211 JBrowse link
G Mfn2 mitofusin 2 ISO RGD PMID:26415228 RGD:13204741 NCBI chrNW_004936474:767,754...795,258 JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO RGD PMID:9780001 RGD:2316946 NCBI chrNW_004936486:16,744,607...16,923,209 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO RGD PMID:27681750 RGD:13781886 NCBI chrNW_004936479:17,682,070...17,716,713 JBrowse link
G Net1 neuroepithelial cell transforming 1 involved_in ISO (PMID:21373644) UniProt PMID:21373644 NCBI chrNW_004936484:9,027,515...9,056,571 JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004936518:6,620,325...6,626,328 JBrowse link
G Rad51 RAD51 recombinase involved_in ISO (PMID:23509288), (PMID:23754376) UniProt PMID:23509288 PMID:23754376 NCBI chrNW_004936471:4,119,020...4,136,811 JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in ISO (PMID:23754376) UniProt PMID:23754376 NCBI chrNW_004936606:4,697,369...4,716,006 JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004936599:2,348,869...2,353,907 JBrowse link
G Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004936606:3,201,540...3,208,019 JBrowse link
G Rhob ras homolog family member B involved_in ISO (PMID:21373644) UniProt PMID:21373644 NCBI chrNW_004936493:10,987,801...10,990,207 JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (MGI:5882892|PMID:16213212) CAFA PMID:16213212 MGI:5882892 NCBI chrNW_004936595:1,603,913...1,609,125 JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5297784|PMID:17612497) UniProt PMID:17612497 MGI:5297784 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (MGI:3690827|PMID:16286009) MGI PMID:16286009 MGI:3690827 NCBI chrNW_004936590:3,813,916...3,817,642 JBrowse link
G Spidr scaffold protein involved in DNA repair involved_in ISO (PMID:23509288), (PMID:23754376) UniProt PMID:23509288 PMID:23754376 NCBI chrNW_004936590:4,921,755...5,041,573 JBrowse link
G Swi5 SWI5 homologous recombination repair protein involved_in ISO (PMID:23754376) UniProt PMID:23754376 NCBI chrNW_004936487:15,814,463...15,822,783 JBrowse link
G Tank TRAF family member associated NFKB activator involved_in ISO (PMID:25861989) UniProt PMID:25861989 NCBI chrNW_004936469:17,665,604...17,754,845 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within ISO (MGI:3842254|PMID:17916808) RGD
MGI
PMID:17916808 PMID:25600523 MGI:3842254 RGD:11073671 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 involved_in ISO (PMID:25749521) BHF-UCL PMID:25749521 NCBI chrNW_004936581:5,158,424...5,182,099 JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:20160708)
(MGI:5882892|PMID:16213212)
(MGI:3690827|PMID:16286009)
BHF-UCL
CAFA
MGI
PMID:16213212 PMID:16286009 PMID:20160708 MGI:3690827 MGI:5882892 NCBI chrNW_004936595:919,807...935,367 JBrowse link
cellular response to X-ray term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:26323318) ParkinsonsUK-UCL PMID:26323318 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Ccnd2 cyclin D2 acts_upstream_of_or_within ISO (MGI:5500853|PMID:23714078) MGI PMID:23714078 MGI:5500853 NCBI chrNW_004936606:4,474,801...4,496,158 JBrowse link
G Dbn1 drebrin 1 ISO RGD PMID:23578130 RGD:10398817 NCBI chrNW_004936597:1,735,589...1,751,628 JBrowse link
G Dnm2 dynamin 2 ISO RGD PMID:15994918 RGD:9685147 NCBI chrNW_004936659:957,408...1,046,393 JBrowse link
G Kat5 lysine acetyltransferase 5 ISO RGD PMID:15985650 RGD:2316135 NCBI chrNW_004936599:3,767,526...3,775,416 JBrowse link
G Lcn2 lipocalin 2 ISO RGD PMID:23331620 RGD:126790570 NCBI chrNW_004936487:15,721,752...15,725,396 JBrowse link
G LOC101972117 hepcidin antimicrobial peptide ISO RGD PMID:17090718 RGD:11041722 NCBI chrNW_004936570:1,009,344...1,010,654 JBrowse link
G Nipbl NIPBL cohesin loading factor involved_in ISO (PMID:17468178) UniProt PMID:17468178 NCBI chrNW_004936518:4,870,686...5,041,099 JBrowse link
G Nucks1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in ISO (PMID:26323318) ParkinsonsUK-UCL PMID:26323318 NCBI chrNW_004936557:6,713,065...6,728,011 JBrowse link
G Prap1 proline rich acidic protein 1 involved_in ISO (MGI:6694360|PMID:32629119) UniProt PMID:32629119 MGI:6694360 NCBI chrNW_004936486:19,477,278...19,480,387 JBrowse link
G Sfrp1 secreted frizzled related protein 1 involved_in ISO (MGI:4835111|PMID:19778523) UniProt PMID:19778523 MGI:4835111 NCBI chrNW_004936785:1,276,478...1,320,397 JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in ISO (MGI:4835111|PMID:19778523) UniProt PMID:19778523 MGI:4835111 NCBI chrNW_004936576:604,174...612,440 JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO RGD PMID:21915754 RGD:9586753 NCBI chrNW_004936471:6,589,395...6,668,242 JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO RGD PMID:11966321 RGD:727219 NCBI chrNW_004936586:1,055,478...1,137,924 JBrowse link
G Xrcc6 X-ray repair cross complementing 6 ISO RGD PMID:11175667 RGD:2317102 NCBI chrNW_004936492:303,843...325,812 JBrowse link
negative regulation of response to gamma radiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO RGD PMID:22981234 RGD:8696027 NCBI chrNW_004936590:4,722,914...4,887,615 JBrowse link
positive regulation of cellular response to X-ray term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmga2 high mobility group AT-hook 2 involved_in ISO (PMID:16061642) UniProt PMID:16061642 NCBI chrNW_004936545:3,944,419...3,958,289 JBrowse link
regulation of cellular response to gamma radiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase ISO RGD PMID:28007901 RGD:12879399 NCBI chrNW_004936551:359,134...534,672 JBrowse link
regulation of cellular response to X-ray term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19735555) UniProt PMID:19735555 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
response to gamma radiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO (MGI:3057047|PMID:15480992) MGI PMID:15480992 MGI:3057047 NCBI chrNW_004939393:628...6,234 JBrowse link
G Bak1 BCL2 antagonist/killer 1 acts_upstream_of_or_within ISO (MGI:3722566|PMID:17068116) MGI PMID:17068116 MGI:3722566 NCBI chrNW_004936476:25,347,608...25,354,772 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:3722566|PMID:17068116) MGI PMID:17068116 MGI:3722566 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within ISO (MGI:1858868|PMID:10815637), (MGI:2156164|PMID:8170972), (MGI:3722566|PMID:17068116), (MGI:62849|PMID:8372353) MGI PMID:8170972 PMID:8372353 PMID:10815637 PMID:17068116 MGI:1858868 MGI:2156164 MGI:3722566 MGI:62849 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Brca2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (MGI:1277623|PMID:9699678)
(MGI:87113|PMID:9126738)
MGI PMID:9126738 PMID:9699678 MGI:1277623 MGI:87113 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Casp6 caspase 6 ISO RGD PMID:10590178 RGD:2301333 NCBI chrNW_004936563:912,502...920,025 JBrowse link
G Cav1 caveolin 1 ISO RGD PMID:17993744 RGD:2289115 NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Cbl Cbl proto-oncogene ISO RGD PMID:16301331 RGD:1579837 NCBI chrNW_004936542:4,136,389...4,235,746 JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO (MGI:3032464|PMID:14744935) MGI PMID:14744935 MGI:3032464 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO RGD PMID:19084914 RGD:2306303 NCBI chrNW_004936676:60,869...63,028 JBrowse link
G Dcun1d3 defective in cullin neddylation 1 domain containing 3 involved_in ISO (PMID:18823379) UniProt PMID:18823379 NCBI chrNW_004936501:6,134,221...6,168,641 JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO (MGI:3054497|PMID:15340056) MGI PMID:15340056 MGI:3054497 NCBI chrNW_004936728:706,499...843,447 JBrowse link
G Fancd2 FA complementation group D2 involved_in ISO (PMID:12874027) UniProt PMID:12874027 NCBI chrNW_004936602:3,162,177...3,220,468 JBrowse link
G Gata3 GATA binding protein 3 ISO RGD PMID:19084914 RGD:2306303 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within ISO (MGI:3044494|PMID:15182862) MGI PMID:15182862 MGI:3044494 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:16524844 RGD:2311096 NCBI chrNW_004936783:1,210,715...1,218,315 JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:16524844 RGD:2311096 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il6r interleukin 6 receptor ISO RGD PMID:14751512 RGD:1625440 NCBI chrNW_004936580:4,055,438...4,081,876 JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (MGI:1312981|PMID:9823897), (MGI:1860400|PMID:10911993) MGI PMID:9823897 PMID:10911993 MGI:1312981 MGI:1860400 NCBI chrNW_004936472:3,861,833...3,867,943 JBrowse link
G LOC101975820 cholesterol side-chain cleavage enzyme, mitochondrial ISO 137 cesium RGD PMID:18046538 RGD:4831839 NCBI chrNW_004936471:33,367,810...33,380,764 JBrowse link
G Men1 menin 1 involved_in ISO (PMID:12874027) UniProt PMID:12874027 NCBI chrNW_004936599:4,504,489...4,510,085 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19179467) UniProt PMID:19179467 NCBI chrNW_004936470:20,480,844...20,485,955 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:14994994 RGD:10414067 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO (MGI:1306978|PMID:9806545)
(MGI:3701394|PMID:11025664)
MGI PMID:9806545 PMID:11025664 MGI:1306978 MGI:3701394 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Polb DNA polymerase beta ISO RGD PMID:12425958 RGD:8694104 NCBI chrNW_004936785:324,655...350,496 JBrowse link
G Polg DNA polymerase gamma, catalytic subunit ISO RGD PMID:12425958 RGD:8694104 NCBI chrNW_004936483:15,178,947...15,196,277 JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO (MGI:4822286|PMID:20647423) UniProt PMID:20647423 MGI:4822286 NCBI chrNW_004936518:1,817,051...1,843,376 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO (MGI:1290043|PMID:9768755) MGI PMID:9768755 MGI:1290043 NCBI chrNW_004936590:4,722,914...4,887,615 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C ISO RGD PMID:17290791 RGD:1599984 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO RGD PMID:14751512 PMID:16937495 RGD:1625440 RGD:2298916 NCBI chrNW_004936594:2,932,297...2,935,358 JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO (MGI:3044494|PMID:15182862) MGI PMID:15182862 MGI:3044494 NCBI chrNW_004936489:11,178,338...11,191,601 JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:5498602|PMID:23726973) MGI PMID:23726973 MGI:5498602 NCBI chrNW_004936606:4,518,525...4,540,109 JBrowse link
G Top1 DNA topoisomerase I ISO RGD PMID:2853856 RGD:2317066 NCBI chrNW_004936561:641,451...723,323 JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:7958916)
(MGI:3722566|PMID:17068116)
(MGI:3032464|PMID:14744935)
BHF-UCL
MGI
PMID:7958916 PMID:14744935 PMID:17068116 MGI:3032464 MGI:3722566 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Trim13 tripartite motif containing 13 involved_in ISO (PMID:21333377) UniProt PMID:21333377 NCBI chrNW_004936565:2,976,681...2,989,036 JBrowse link
G Xrcc2 X-ray repair cross complementing 2 acts_upstream_of_or_within ISO (MGI:3652689|PMID:16777961) MGI PMID:16777961 MGI:3652689 NCBI chrNW_004936527:7,760,609...7,785,360 JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (MGI:1913213|PMID:9875844) MGI PMID:9875844 MGI:1913213 NCBI chrNW_004936469:2,248,367...2,495,215 JBrowse link
response to X-ray term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 ISO RGD PMID:9269316 RGD:2306948 NCBI chrNW_004936503:9,124,314...9,142,372 JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:11309417) UniProt PMID:11309417 NCBI chrNW_004936483:16,194,092...16,295,803 JBrowse link
G Brca2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (MGI:1100157|PMID:9398843)
(MGI:3833141|PMID:16859999)
(MGI:1203345|PMID:9660919)
MGI PMID:9398843 PMID:9660919 PMID:16859999 MGI:1100157 MGI:1203345 MGI:3833141 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 acts_upstream_of_or_within ISO (PMID:14636569) MGI PMID:14636569 NCBI chrNW_004936927:341,114...380,817 JBrowse link
G Casp3 caspase 3 ISO RGD PMID:18239382 RGD:2293328 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G Ccnd1 cyclin D1 ISO RGD PMID:17148264 RGD:1601086
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO RGD PMID:18413982 RGD:8662408 NCBI chrNW_004936476:22,717,308...22,725,127 JBrowse link
G Col2a1 collagen type II alpha 1 chain ISO RGD PMID:17549535 RGD:8661655 NCBI chrNW_004936512:5,861,933...5,894,898 JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO (MGI:3613277|PMID:15979950) MGI PMID:15979950 MGI:3613277 NCBI chrNW_004936706:1,854,938...1,867,521 JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO (MGI:3613277|PMID:15979950), (MGI:3699047|PMID:17145777) MGI PMID:15979950 PMID:17145777 MGI:3613277 MGI:3699047 NCBI chrNW_004936728:706,499...843,447 JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit acts_upstream_of_or_within ISO (MGI:3699047|PMID:17145777) MGI PMID:17145777 MGI:3699047 NCBI chrNW_004936480:7,560,055...7,609,650 JBrowse link
G Fga fibrinogen alpha chain ISO RGD PMID:4170424 RGD:11040910 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO RGD PMID:15161688 RGD:9068912 NCBI chrNW_004936495:5,770,988...5,816,157 JBrowse link
G Il7 interleukin 7 ISO RGD PMID:15799696 RGD:10402940 NCBI chrNW_004936702:110,625...162,957 JBrowse link
G Kars1 lysyl-tRNA synthetase 1 ISO RGD PMID:4001316 RGD:12910553 NCBI chrNW_004936475:24,294,699...24,312,051 JBrowse link
G Lig4 DNA ligase 4 involved_in ISO (PMID:9809069) UniProt PMID:9809069 NCBI chrNW_004936472:3,861,833...3,867,943 JBrowse link
G LOC101976500 haptoglobin ISO RGD PMID:12379430 RGD:1626377 NCBI chrNW_004936475:21,841,054...21,845,821 JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:12121845 RGD:1641839 NCBI chrNW_004936469:10,245,001...10,438,933 JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO (MGI:2667543|PMID:12687013) MGI PMID:12687013 MGI:2667543 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Pdxk pyridoxal kinase ISO RGD PMID:2928487 RGD:2303016 NCBI chrNW_004936500:510,977...539,166 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO (MGI:2675761|PMID:12952892) MGI PMID:12952892 MGI:2675761 NCBI chrNW_004936497:4,985,995...4,986,720 JBrowse link
G Rad51 RAD51 recombinase ISO RGD PMID:17148264 RGD:1601086 NCBI chrNW_004936471:4,119,020...4,136,811 JBrowse link
G Thbd thrombomodulin ISO RGD PMID:12057911 RGD:634507 NCBI chrNW_004936620:2,563,900...2,568,117 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:3032953|PMID:11884608)
(MGI:5440773|PMID:22821713)
RGD
MGI
PMID:11884608 PMID:17699727 PMID:22821713 MGI:3032953 MGI:5440773 RGD:2290567 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Vwf von Willebrand factor ISO RGD PMID:8811296 RGD:11079207 NCBI chrNW_004936709:1,578,137...1,741,877 JBrowse link
G Xrcc2 X-ray repair cross complementing 2 acts_upstream_of_or_within ISO (MGI:3613277|PMID:15979950) MGI PMID:15979950 MGI:3613277 NCBI chrNW_004936527:7,760,609...7,785,360 JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in
acts_upstream_of_or_within
ISO (PMID:9242410)
(MGI:1913213|PMID:9875844)
UniProt
MGI
PMID:9242410 PMID:9875844 MGI:1913213 NCBI chrNW_004936469:2,248,367...2,495,215 JBrowse link
G Xrra1 X-ray radiation resistance associated 1 involved_in ISO (PMID:12908878) UniProt PMID:12908878 NCBI chrNW_004936498:3,783,623...3,844,674 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12170
    response to stimulus 6550
      response to abiotic stimulus 1365
        response to radiation 513
          response to ionizing radiation 181
            cellular response to ionizing radiation + 80
            response to X-ray + 45
            response to gamma radiation + 68
paths to the root