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ONTOLOGY REPORT - ANNOTATIONS


Term:response to iron ion
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Accession:GO:0010039 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: response to iron



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response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IDA RGD PMID:9719948 RGD:1598519 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 IEP RGD PMID:15637178 RGD:2315589 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Alad aminolevulinate dehydratase IEP RGD PMID:14598909 RGD:4144204 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 IEP RGD PMID:18723004 RGD:2301196 NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO (PMID:11264898) RGD PMID:11264898 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bmp6 bone morphogenetic protein 6 IEP RGD PMID:21859731 RGD:7242407 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G C1qa complement C1q A chain IEP RGD PMID:18723004 RGD:2301196 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G Casp6 caspase 6 IMP RGD PMID:17571084 RGD:2301311 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Ccnd1 cyclin D1 IEP RGD PMID:16890145 RGD:1582331 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cpox coproporphyrinogen oxidase IEP RGD PMID:2289051 RGD:1600959 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746
JBrowse link
G Cybrd1 cytochrome b reductase 1 acts_upstream_of_or_within ISO (MGI:2654570|PMID:11230685) RGD PMID:11230685 MGI:2654570 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108
JBrowse link
G Dbh dopamine beta-hydroxylase IEP RGD PMID:18363828 RGD:5129689 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Drd2 dopamine receptor D2 IEP RGD PMID:19022977 RGD:2311557 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A IEP RGD PMID:17546681 RGD:2302076 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fn1 fibronectin 1 IEP RGD PMID:18723004 RGD:2301196 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fxn frataxin involved_in IEA
ISO
GO_REF:0000107
(PMID:18424449)
Ensembl
RGD
PMID:18424449 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,841
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:12469120) RGD PMID:12469120 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:21173098) RGD PMID:21173098 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA
(PMID:28296633)
GO_REF:0000107
RGD
Ensembl
PMID:28296633 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Mdm2 MDM2 proto-oncogene IEP RGD PMID:20019189 RGD:2317357 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Ngb neuroglobin IEP RGD PMID:23231908 RGD:9831163 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830
JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in
NOT|involved_in
IEP
IEA
ISO
GO_REF:0000107
(PMID:12209011), (PMID:15792797), (PMID:18082289)
(PMID:15792797)
(PMID:12734107), (PMID:17109629)
Ensembl
RGD
PMID:12209011 PMID:12734107 PMID:15792797 PMID:17109629 PMID:18082289 More... GO_REF:0000107, RGD:1580429 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc6a3 solute carrier family 6 member 3 IEP RGD PMID:12672939 RGD:1625670 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Tff1 trefoil factor 1 IEP RGD PMID:16629162 RGD:1599392 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:21173098) RGD PMID:21173098 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
JBrowse link
G Tfrc transferrin receptor IEP RGD PMID:17060373 PMID:23635304 RGD:2292035, RGD:7244375 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Urod uroporphyrinogen decarboxylase IEP in hexachlorobenzene-treated rats RGD PMID:891100 RGD:4145101 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808
JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha IEP RGD PMID:23174565 PMID:19679821 RGD:11341702, RGD:11341808 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G B2m beta-2 microglobulin involved_in ISO UniProtKB:P02787|UniProtKB:Q07891|UniProtKB:Q30201|UniProtKB:Q9UP52 (PMID:18353247) RGD PMID:18353247 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (MGI:4352622|PMID:19252488) RGD PMID:19252488 MGI:4352622 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P02787|UniProtKB:P61769|UniProtKB:Q07891|UniProtKB:Q9UP52 (PMID:18353247) RGD PMID:18353247 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Slc11a2 solute carrier family 11 member 2 IEP RGD PMID:17663481 RGD:5688717 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Tf transferrin involved_in ISO UniProtKB:Q07891|UniProtKB:Q9UP52 (PMID:18353247) RGD PMID:18353247 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISS
ISO
GO_REF:0000024
(PMID:20808827)
UniProt
RGD
PMID:20808827 GO_REF:0000024 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tfr2 transferrin receptor 2 involved_in ISO UniProtKB:P02787|UniProtKB:Q07891 (PMID:18353247) RGD PMID:18353247 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IDA PMID:1849823 UniProt PMID:1849823 RGD:8553426 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IEP RGD PMID:19608791 RGD:10045561 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO MGI:1927183 (MGI:1203460|PMID:9531620) RGD PMID:9531620 MGI:1203460 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Ccnb1 cyclin B1 IEP ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP
IDA
RGD PMID:17469137 PMID:16135072 RGD:12904039, RGD:12904046 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP RGD PMID:21683124 RGD:7207286 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:21683124 RGD:7207286 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to iron term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within ISO (MGI:5527134|PMID:23395172) RGD PMID:23395172 MGI:5527134 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hrg histidine-rich glycoprotein acts_upstream_of_or_within ISO (MGI:5527134|PMID:23395172) RGD PMID:23395172 MGI:5527134 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Slc40a1 solute carrier family 40 member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5527134|PMID:23395172)
GO_REF:0000107
RGD
Ensembl
PMID:23395172 GO_REF:0000107 MGI:5527134 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 involved_in ISO
ISS
(PMID:8041788)
GO_REF:0000024
RGD
UniProt
PMID:8041788 GO_REF:0000024 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Atg5 autophagy related 5 IEP RGD PMID:23187302 RGD:11561914 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Becn1 beclin 1 IEP RGD PMID:23187302 RGD:11561914 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP RGD PMID:19943190 RGD:6893272 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Lcn2 lipocalin 2 IEP RGD PMID:23416150 RGD:126790480 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lct lactase IDA RGD PMID:16081762 RGD:1600248 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:23187302 RGD:11561914 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP RGD PMID:10349840 RGD:9835366 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IEP RGD PMID:16081762 RGD:1600248 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEP FeSO4 RGD PMID:17600839 RGD:4108504 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:11850416) RGD PMID:11850416 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha IEP RGD PMID:16629162 RGD:1599392 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Casp12 caspase 12 IEP RGD PMID:19594550 RGD:2311452 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP Hematite RGD PMID:15211619 RGD:2306667 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEP RGD PMID:24599681 RGD:10449122 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gsr glutathione-disulfide reductase IEP RGD PMID:24388910 RGD:11059508 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Ireb2 iron responsive element binding protein 2 IDA RGD PMID:21753061 RGD:12904028 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19896
    response to stimulus 10568
      response to chemical 6105
        response to inorganic substance 878
          response to metal ion 546
            response to iron ion 54
              cellular response to iron ion + 17
              detoxification of iron ion 0
              response to iron(II) ion + 13
              response to iron(III) ion + 10
paths to the root