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ONTOLOGY REPORT - ANNOTATIONS

Term:cardioblast differentiation
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Accession:GO:0010002 term browser browse the term
Definition:The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
Synonyms:exact_synonym: cardiac precursor cell differentiation;   cardioblast cell differentiation
 related_synonym: cardiomyocyte generation


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cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin acts_upstream_of_or_within ISO MGI:3774028 (PMID:21822279) RGD PMID:21822279 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
ISS		 (PMID:15896309)
GO_REF:0000024		 RGD
UniProt		 PMID:15896309 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (MGI:5315691|PMID:18545679) RGD PMID:18545679 MGI:5315691 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19620969)		 Ensembl
RGD		 PMID:19620969 GO_REF:0000107 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2154539 (PMID:9004034)		 Ensembl
RGD		 PMID:9004034 GO_REF:0000107 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Myocd myocardin involved_in ISO
IEA		 (PMID:15907818)
GO_REF:0000107		 RGD
Ensembl		 PMID:15907818 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:4947514|PMID:20007915) RGD PMID:20007915 MGI:4947514 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO
IEA		 (PMID:17336907)
GO_REF:0000107		 RGD
Ensembl		 PMID:17336907 GO_REF:0000107 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Rbm10 RNA binding motif protein 10 IEP RGD PMID:24178303 RGD:151667450 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:5298073|PMID:21311046) RGD PMID:21311046 MGI:5298073 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009770|PMID:21199191)		 UniProt
RGD		 PMID:21199191 GO_REF:0000024 MGI:5009770 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G Srf serum response factor involved_in ISO UniProtKB:Q9JM73 (PMID:19783823)
UniProtKB:P11831 (MGI:5009475|PMID:19783823)		 RGD PMID:19783823 MGI:5009475 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:3487212|PMID:15459098) RGD PMID:15459098 MGI:3487212 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Tbxt T-box transcription factor T involved_in ISO (PMID:21632880)
(MGI:5307952|PMID:21632880)		 RGD PMID:21632880 MGI:5307952 NCBI chr 1:52,298,104...52,309,813
Ensembl chr 1:52,298,099...52,305,864 		JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA		 (PMID:21199191)
GO_REF:0000107		 RGD
Ensembl		 PMID:21199191 GO_REF:0000107 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6201954|PMID:26489465)		 UniProt
RGD		 PMID:26489465 GO_REF:0000024 MGI:6201954 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3784761|PMID:11889119)		 Ensembl
RGD		 PMID:11889119 GO_REF:0000107 MGI:3784761 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:11431700)		 UniProt
Ensembl
RGD		 PMID:11431700 GO_REF:0000024 GO_REF:0000107 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15896309)		 AgBase
RGD		 PMID:15896309 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      cellular developmental process 4768
        cell differentiation 4767
          cardiocyte differentiation 207
            cardioblast differentiation 18
              cardiac muscle cell myoblast differentiation + 13
              cardioblast cell fate commitment + 0
              endocardial precursor cell differentiation 0
              negative regulation of cardioblast differentiation + 1
              positive regulation of cardioblast differentiation + 4
              regulation of cardioblast differentiation + 5
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            circulatory system development 1378
              heart development 747
                cardiocyte differentiation 207
                  cardioblast differentiation 18
                    cardiac muscle cell myoblast differentiation + 13
                    cardioblast cell fate commitment + 0
                    endocardial precursor cell differentiation 0
                    negative regulation of cardioblast differentiation + 1
                    positive regulation of cardioblast differentiation + 4
                    regulation of cardioblast differentiation + 5
paths to the root