Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cardioblast differentiation
go back to main search page
Accession:GO:0010002 term browser browse the term
Definition:The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
Synonyms:exact_synonym: cardiac precursor cell differentiation;   cardioblast cell differentiation
 related_synonym: cardiomyocyte generation


show annotations for term's descendants           Sort by:
 
cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ECE2 endothelin converting enzyme 2 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 3:184,276,022...184,293,031
Ensembl chr 3:184,276,011...184,293,031
JBrowse link
G EEF1AKMT4-ECE2 EEF1AKMT4-ECE2 readthrough involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 3:184,249,672...184,293,031
Ensembl chr 3:184,249,695...184,293,031
JBrowse link
G EOMES eomesodermin acts_upstream_of_or_within ISO (MGI:5293253|PMID:21822279) MGI PMID:21822279 MGI:5293253 NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IDA (PMID:15896309) UniProt PMID:15896309 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ISL1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4438134|PMID:19620969) Ensembl
MGI
PMID:19620969 GO_REF:0000107 MGI:4438134 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730
JBrowse link
G NRG1 neuregulin 1 involved_in IDA (PMID:17336907) BHF-UCL PMID:17336907 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
JBrowse link
G REST RE1 silencing transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:56,907,900...56,935,847
Ensembl chr 4:56,907,876...56,966,808
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IDA (PMID:21199191) UniProt PMID:21199191 NCBI chr12:42,456,757...42,589,755
Ensembl chr12:42,456,757...42,590,355
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in IDA (PMID:19736317) BHF-UCL PMID:19736317 NCBI chr 1:228,006,998...228,067,113
Ensembl chr 1:228,006,998...228,061,271
JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHX36 DEAH-box helicase 36 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:154,272,546...154,324,487
Ensembl chr 3:154,272,546...154,324,487
JBrowse link
G GATA4 GATA binding protein 4 involved_in
acts_upstream_of_or_within
ISS
ISO
(PMID:16137232) BHF-UCL
BHF-UCL
PMID:16137232 GO_REF:0000024 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16137232) Ensembl
BHF-UCL
PMID:16137232 GO_REF:0000107 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in ISS (PMID:8900537) BHF-UCL PMID:8900537 NCBI chr 5:173,232,109...173,235,321
Ensembl chr 5:173,232,109...173,235,311
JBrowse link
G TBX5 T-box transcription factor 5 involved_in IDA (PMID:11431700) UniProt PMID:11431700 NCBI chr12:114,353,911...114,408,708
Ensembl chr12:114,353,911...114,408,442
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IDA (PMID:15896309) UniProt PMID:15896309 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISS (PMID:9660951) BHF-UCL PMID:9660951 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106
JBrowse link
G MYOCD myocardin involved_in IDA (PMID:15907818) BHF-UCL PMID:15907818 NCBI chr17:12,665,890...12,768,949
Ensembl chr17:12,665,890...12,768,949
JBrowse link
G SRF serum response factor involved_in IGI (PMID:19783823) BHF-UCL PMID:19783823 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506
JBrowse link
G TBXT T-box transcription factor T involved_in IDA
IEA
(PMID:21632880) BHF-UCL
Ensembl
PMID:21632880 GO_REF:0000107 NCBI chr 6:166,157,656...166,168,655
Ensembl chr 6:166,157,656...166,168,700
JBrowse link
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOTCH1 notch receptor 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 4:26,163,458...26,435,131
Ensembl chr 4:26,163,455...26,435,131
JBrowse link
G TBX2 T-box transcription factor 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:61,399,843...61,409,466
Ensembl chr17:61,399,843...61,409,466
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18666
    cellular process 17730
      cellular developmental process 5046
        cell differentiation 4942
          cardiocyte differentiation 188
            cardioblast differentiation 21
              cardiac muscle cell myoblast differentiation + 11
              cardioblast cell fate commitment + 1
              endocardial precursor cell differentiation + 0
              negative regulation of cardioblast differentiation + 2
              positive regulation of cardioblast differentiation + 6
              regulation of cardioblast differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 18666
    developmental process 7387
      anatomical structure development 6725
        multicellular organism development 6121
          system development 5805
            circulatory system development 1297
              heart development 722
                cardiocyte differentiation 188
                  cardioblast differentiation 21
                    cardiac muscle cell myoblast differentiation + 11
                    cardioblast cell fate commitment + 1
                    endocardial precursor cell differentiation + 0
                    negative regulation of cardioblast differentiation + 2
                    positive regulation of cardioblast differentiation + 6
                    regulation of cardioblast differentiation + 8
paths to the root