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ONTOLOGY REPORT - ANNOTATIONS


Term:cardioblast differentiation
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Accession:GO:0010002 term browser browse the term
Definition:The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
Synonyms:exact_synonym: cardiac precursor cell differentiation;   cardioblast cell differentiation
 related_synonym: cardiomyocyte generation



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cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin acts_upstream_of_or_within ISO MGI:3774028 (MGI:5293253|PMID:21822279) RGD PMID:21822279 MGI:5293253 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
ISS
(PMID:15896309)
GO_REF:0000024
RGD
UniProt
PMID:15896309 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO
IEA
(MGI:5315691|PMID:18545679)
GO_REF:0000107
RGD
Ensembl
PMID:18545679 GO_REF:0000107 MGI:5315691 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO (MGI:4438134|PMID:19620969) RGD PMID:19620969 MGI:4438134 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Itgb1 integrin subunit beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2154539 (MGI:84974|PMID:9004034)
GO_REF:0000107
RGD
Ensembl
PMID:9004034 GO_REF:0000107 MGI:84974 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Myocd myocardin involved_in ISO
IEA
(PMID:15907818)
GO_REF:0000107
RGD
Ensembl
PMID:15907818 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA
(MGI:4947514|PMID:20007915)
GO_REF:0000107
RGD
Ensembl
PMID:20007915 GO_REF:0000107 MGI:4947514 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nrg1 neuregulin 1 involved_in ISO
IEA
(PMID:17336907)
GO_REF:0000107
RGD
Ensembl
PMID:17336907 GO_REF:0000107 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Rbm10 RNA binding motif protein 10 IEP RGD PMID:24178303 RGD:151667450 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:5298073|PMID:21311046) RGD PMID:21311046 MGI:5298073 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:5009770|PMID:21199191)
UniProt
RGD
PMID:21199191 GO_REF:0000024 MGI:5009770 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
G Srf serum response factor involved_in ISO
IEA
UniProtKB:Q9JM73 (PMID:19783823)
GO_REF:0000107
UniProtKB:P11831 (MGI:5009475|PMID:19783823)
RGD
Ensembl
PMID:19783823 GO_REF:0000107 MGI:5009475 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO
IEA
(MGI:3487212|PMID:15459098)
GO_REF:0000107
RGD
Ensembl
PMID:15459098 GO_REF:0000107 MGI:3487212 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
G Tbxt T-box transcription factor T involved_in ISO
IEA
(PMID:21632880)
GO_REF:0000107
(MGI:5307952|PMID:21632880)
RGD
Ensembl
PMID:21632880 GO_REF:0000107 MGI:5307952 NCBI chr 1:52,298,099...52,309,813
Ensembl chr 1:52,298,099...52,305,864
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA
(PMID:21199191)
GO_REF:0000107
RGD
Ensembl
PMID:21199191 GO_REF:0000107 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 involved_in ISS
ISO
GO_REF:0000024
(MGI:6201954|PMID:26489465)
UniProt
RGD
PMID:26489465 GO_REF:0000024 MGI:6201954 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO (PMID:16137232) RGD PMID:16137232 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16137232)
Ensembl
RGD
PMID:16137232 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3784761|PMID:11889119)
Ensembl
RGD
PMID:11889119 GO_REF:0000107 MGI:3784761 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:11431700)
UniProt
Ensembl
RGD
PMID:11431700 GO_REF:0000024 GO_REF:0000107 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:15896309)
AgBase
RGD
PMID:15896309 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      cellular developmental process 4534
        cell differentiation 4511
          cardiocyte differentiation 202
            cardioblast differentiation 21
              cardiac muscle cell myoblast differentiation + 13
              cardioblast cell fate commitment + 1
              endocardial precursor cell differentiation 0
              negative regulation of cardioblast differentiation + 2
              positive regulation of cardioblast differentiation + 6
              regulation of cardioblast differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure development 6372
        multicellular organism development 5440
          system development 4941
            circulatory system development 1324
              heart development 716
                cardiocyte differentiation 202
                  cardioblast differentiation 21
                    cardiac muscle cell myoblast differentiation + 13
                    cardioblast cell fate commitment + 1
                    endocardial precursor cell differentiation 0
                    negative regulation of cardioblast differentiation + 2
                    positive regulation of cardioblast differentiation + 6
                    regulation of cardioblast differentiation + 8
paths to the root