Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cardioblast differentiation
go back to main search page
Accession:GO:0010002 term browser browse the term
Definition:The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
Synonyms:exact_synonym: cardiac precursor cell differentiation;   cardioblast cell differentiation
 related_synonym: cardiomyocyte generation


show annotations for term's descendants           Sort by:
 
cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin acts_upstream_of_or_within ISO MGI:3774028 (MGI:5293253|PMID:21822279) RGD PMID:21822279 MGI:5293253 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
ISS
(PMID:15896309)
GO_REF:0000024
RGD
AgBase
PMID:15896309 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO (MGI:4438134|PMID:19620969) RGD PMID:19620969 MGI:4438134 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Nrg1 neuregulin 1 involved_in ISO
IEA
(PMID:17336907)
GO_REF:0000107
RGD
Ensembl
PMID:17336907 GO_REF:0000107 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:5009770|PMID:21199191)
UniProt
RGD
PMID:21199191 GO_REF:0000024 MGI:5009770 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA
(PMID:21199191)
GO_REF:0000107
RGD
Ensembl
PMID:21199191 GO_REF:0000107 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 involved_in ISS
ISO
GO_REF:0000024
(MGI:6201954|PMID:26489465)
UniProt
RGD
PMID:26489465 GO_REF:0000024 MGI:6201954 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO (PMID:16137232) RGD PMID:16137232 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16137232)
Ensembl
RGD
PMID:16137232 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3784761|PMID:11889119)
Ensembl
RGD
PMID:11889119 GO_REF:0000107 MGI:3784761 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:11431700)
UniProt
Ensembl
RGD
PMID:11431700 GO_REF:0000024 GO_REF:0000107 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:15896309)
UniProt
RGD
PMID:15896309 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (MGI:5315691|PMID:18545679) RGD PMID:18545679 MGI:5315691 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Myocd myocardin involved_in ISO
IEA
(PMID:15907818)
GO_REF:0000107
RGD
Ensembl
PMID:15907818 GO_REF:0000107 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
G Srf serum response factor involved_in ISO UniProtKB:Q9JM73 (PMID:19783823)
(MGI:5009475|PMID:19783823)
RGD PMID:19783823 MGI:5009475 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Tbxt T-box transcription factor T involved_in ISO (PMID:21632880)
(MGI:5307952|PMID:21632880)
RGD PMID:21632880 MGI:5307952 NCBI chr 1:52,887,067...52,900,691
Ensembl chr 1:52,887,067...52,894,832
JBrowse link
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO (MGI:4947514|PMID:20007915) RGD PMID:20007915 MGI:4947514 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:5298073|PMID:21311046) RGD PMID:21311046 MGI:5298073 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:3487212|PMID:15459098) RGD PMID:15459098 MGI:3487212 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      cellular developmental process 4461
        cell differentiation 4365
          cardiocyte differentiation 184
            cardioblast differentiation 19
              cardiac muscle cell myoblast differentiation + 11
              cardioblast cell fate commitment + 1
              endocardial precursor cell differentiation + 0
              negative regulation of cardioblast differentiation + 2
              positive regulation of cardioblast differentiation + 6
              regulation of cardioblast differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 19612
    developmental process 6792
      anatomical structure development 6265
        multicellular organism development 5747
          system development 5290
            circulatory system development 1230
              heart development 692
                cardiocyte differentiation 184
                  cardioblast differentiation 19
                    cardiac muscle cell myoblast differentiation + 11
                    cardioblast cell fate commitment + 1
                    endocardial precursor cell differentiation + 0
                    negative regulation of cardioblast differentiation + 2
                    positive regulation of cardioblast differentiation + 6
                    regulation of cardioblast differentiation + 8
paths to the root