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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell fate specification
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Accession:GO:0009996 term browser browse the term
Definition:Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
Synonyms:exact_synonym: down regulation of cell fate specification;   downregulation of cell fate specification;   suppression of cell fate
 narrow_synonym: inhibition of cell fate specification



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negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 1:92,473,043...92,486,925
Ensembl chr 1:92,473,043...92,486,925
JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FZD7 frizzled class receptor 7 involved_in IMP (PMID:18681827) BHF-UCL PMID:18681827 NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,033,855...202,038,441
JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr15:89,732,446...89,751,249
Ensembl chr15:89,749,875...89,751,249
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IDA (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr15:89,732,446...89,751,249
Ensembl chr15:89,749,875...89,751,249
JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17462603) Ensembl
MGI
PMID:17462603 GO_REF:0000107 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20486
    developmental process 7683
      cellular developmental process 5227
        cell fate specification 124
          negative regulation of cell fate specification 5
            negative regulation of atrichoblast fate specification 0
            negative regulation of auditory receptor cell fate specification 0
            negative regulation of cardiac cell fate specification + 0
            negative regulation of compound eye cone cell fate specification 0
            negative regulation of ectodermal cell fate specification 1
            negative regulation of endodermal cell fate specification 1
            negative regulation of fusion cell fate specification 0
            negative regulation of mesodermal cell fate specification + 3
            negative regulation of neural crest cell fate specification 0
            negative regulation of retinal cone cell fate specification 0
            negative regulation of terminal cell fate specification, open tracheal system 0
            negative regulation of trichoblast fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 20486
    biological regulation 13634
      regulation of biological process 13232
        negative regulation of biological process 6544
          negative regulation of developmental process 1224
            negative regulation of cell differentiation 879
              negative regulation of cell fate commitment 19
                negative regulation of cell fate specification 5
                  negative regulation of atrichoblast fate specification 0
                  negative regulation of auditory receptor cell fate specification 0
                  negative regulation of cardiac cell fate specification + 0
                  negative regulation of compound eye cone cell fate specification 0
                  negative regulation of ectodermal cell fate specification 1
                  negative regulation of endodermal cell fate specification 1
                  negative regulation of fusion cell fate specification 0
                  negative regulation of mesodermal cell fate specification + 3
                  negative regulation of neural crest cell fate specification 0
                  negative regulation of retinal cone cell fate specification 0
                  negative regulation of terminal cell fate specification, open tracheal system 0
                  negative regulation of trichoblast fate specification 0
paths to the root