negative regulation of cell fate specification - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS	{{ watchLinkText }}

Term:	negative regulation of cell fate specification	go back to main search page
Accession:	GO:0009996	browse the term
Definition:	Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
Synonyms:	exact_synonym:	down regulation of cell fate specification; downregulation of cell fate specification; suppression of cell fate
	narrow_synonym:	inhibition of cell fate specification

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Rat (6) Mouse (7) Human (6) Chinchilla (5) Bonobo (6) Dog (6) Squirrel (6) Pig (6) All
Genes (6)

negative regulation of cell fate specification

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Object Name

Evidence

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G

growth factor independent 1 transcriptional repressor

MGI:2449921 (MGI:3606816|PMID:16230531)

NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371

negative regulation of ectodermal cell fate specification

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Evidence

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G

frizzled class receptor 7

(PMID:18681827)

NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550

negative regulation of endodermal cell fate specification

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Object Name

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PubMed Reference(s)

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G

mesoderm posterior bHLH transcription factor 1

(MGI:4441249|PMID:18593560)

NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908

negative regulation of heart induction by canonical Wnt signaling pathway

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G

Wnt family member 3A

(PMID:19736317)

NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035

negative regulation of mesodermal cell fate specification

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Evidence

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PubMed Reference(s)

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G

dickkopf WNT signaling pathway inhibitor 1

(PMID:20559569)

NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607

G

mesoderm posterior bHLH transcription factor 1

(MGI:4441249|PMID:18593560)

NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908

G

secreted frizzled-related protein 2

MGI:98956 (MGI:3711603|PMID:17462603)

NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764

Term paths to the root

Path 1
Term	Annotations
biological_process	20045
developmental process	6824
cellular developmental process	4464
cell fate specification	100
negative regulation of cell fate specification	6
negative regulation of atrichoblast fate specification	0
negative regulation of auditory receptor cell fate specification	0
negative regulation of cardiac cell fate specification +	1
negative regulation of compound eye cone cell fate specification	0
negative regulation of ectodermal cell fate specification	1
negative regulation of endodermal cell fate specification	1
negative regulation of fusion cell fate specification	0
negative regulation of mesodermal cell fate specification +	3
negative regulation of neural crest cell fate specification	0
negative regulation of retinal cone cell fate specification	0
negative regulation of terminal cell fate specification, open tracheal system	0
negative regulation of trichoblast fate specification	0
Path 2
Term	Annotations
biological_process	20045
biological regulation	13855
regulation of biological process	13105
negative regulation of biological process	5685
negative regulation of developmental process	1018
negative regulation of cell differentiation	738
negative regulation of cell fate commitment	16
negative regulation of cell fate specification	6
negative regulation of atrichoblast fate specification	0
negative regulation of auditory receptor cell fate specification	0
negative regulation of cardiac cell fate specification +	1
negative regulation of compound eye cone cell fate specification	0
negative regulation of ectodermal cell fate specification	1
negative regulation of endodermal cell fate specification	1
negative regulation of fusion cell fate specification	0
negative regulation of mesodermal cell fate specification +	3
negative regulation of neural crest cell fate specification	0
negative regulation of retinal cone cell fate specification	0
negative regulation of terminal cell fate specification, open tracheal system	0
negative regulation of trichoblast fate specification	0

paths to the root