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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cell fate specification
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Accession:GO:0009996 term browser browse the term
Definition:Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
Synonyms:exact_synonym: down regulation of cell fate specification;   downregulation of cell fate specification;   suppression of cell fate
 narrow_synonym: inhibition of cell fate specification


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negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO MGI:2449921 (MGI:3606816|PMID:16230531) RGD PMID:16230531 MGI:3606816 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:18681827) RGD PMID:18681827 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:98956 (MGI:3711603|PMID:17462603) RGD PMID:17462603 MGI:3711603 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    developmental process 6893
      cellular developmental process 4533
        cell fate specification 100
          negative regulation of cell fate specification 6
            negative regulation of atrichoblast fate specification 0
            negative regulation of auditory receptor cell fate specification 0
            negative regulation of cardiac cell fate specification + 1
            negative regulation of compound eye cone cell fate specification 0
            negative regulation of ectodermal cell fate specification 1
            negative regulation of endodermal cell fate specification 1
            negative regulation of fusion cell fate specification 0
            negative regulation of mesodermal cell fate specification + 3
            negative regulation of neural crest cell fate specification 0
            negative regulation of retinal cone cell fate specification 0
            negative regulation of terminal cell fate specification, open tracheal system 0
            negative regulation of trichoblast fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        negative regulation of biological process 5769
          negative regulation of developmental process 1080
            negative regulation of cell differentiation 775
              negative regulation of cell fate commitment 16
                negative regulation of cell fate specification 6
                  negative regulation of atrichoblast fate specification 0
                  negative regulation of auditory receptor cell fate specification 0
                  negative regulation of cardiac cell fate specification + 1
                  negative regulation of compound eye cone cell fate specification 0
                  negative regulation of ectodermal cell fate specification 1
                  negative regulation of endodermal cell fate specification 1
                  negative regulation of fusion cell fate specification 0
                  negative regulation of mesodermal cell fate specification + 3
                  negative regulation of neural crest cell fate specification 0
                  negative regulation of retinal cone cell fate specification 0
                  negative regulation of terminal cell fate specification, open tracheal system 0
                  negative regulation of trichoblast fate specification 0
paths to the root