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ONTOLOGY REPORT - ANNOTATIONS
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Term:
negative regulation of cell fate specification
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Accession:
GO:0009996
browse the term
Definition:
Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
Synonyms:
exact_synonym:
down regulation of cell fate specification; downregulation of cell fate specification; suppression of cell fate
narrow_synonym:
inhibition of cell fate specification
show annotations for term's descendants Sort by:
symbol
object name
position
reference
evidence
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Rat (5)
Mouse (6)
Human (5)
Chinchilla (4)
Bonobo (5)
Dog (5)
Squirrel (5)
Pig (5)
Green Monkey (5)
Naked Mole-rat (4)
All
Genes (5)
negative regulation of cell fate specification
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Gfi1
growth factor independent 1 transcriptional repressor
acts_upstream_of_or_within
ISO
MGI:2449921 (PMID:16230531)
RGD
PMID:16230531
NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
negative regulation of ectodermal cell fate specification
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Fzd7
frizzled class receptor 7
involved_in
ISO
(PMID:18681827)
RGD
PMID:18681827
NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
negative regulation of endodermal cell fate specification
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Mesp1
mesoderm posterior bHLH transcription factor 1
involved_in
ISO
(PMID:18593560)
RGD
PMID:18593560
NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
negative regulation of mesodermal cell fate specification
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Dkk1
dickkopf WNT signaling pathway inhibitor 1
involved_in
ISO
(PMID:20559569)
RGD
PMID:20559569
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
G
Mesp1
mesoderm posterior bHLH transcription factor 1
involved_in
ISO
(PMID:18593560)
RGD
PMID:18593560
NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
G
Sfrp2
secreted frizzled-related protein 2
acts_upstream_of_or_within
ISO
MGI:98956 (PMID:17462603)
RGD
PMID:17462603
NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
Term paths to the root
one shortest
all shortest
one longest
all longest
one shortest and longest
all
Path 1
Term
Annotations
biological_process
20075
developmental process
7069
cellular developmental process
4781
cell fate specification
102
negative regulation of cell fate specification
5
negative regulation of atrichoblast fate specification
0
negative regulation of auditory receptor cell fate specification
0
negative regulation of cardiac cell fate specification
+
0
negative regulation of compound eye cone cell fate specification
0
negative regulation of ectodermal cell fate specification
1
negative regulation of endodermal cell fate specification
1
negative regulation of fusion cell fate specification
0
negative regulation of mesodermal cell fate specification
+
3
negative regulation of neural crest cell fate specification
0
negative regulation of retinal cone cell fate specification
0
negative regulation of terminal cell fate specification, open tracheal system
0
negative regulation of trichoblast fate specification
0
Path 2
Term
Annotations
biological_process
20075
biological regulation
13559
regulation of biological process
13136
negative regulation of biological process
5770
negative regulation of developmental process
1106
negative regulation of cell differentiation
797
negative regulation of cell fate commitment
19
negative regulation of cell fate specification
5
negative regulation of atrichoblast fate specification
0
negative regulation of auditory receptor cell fate specification
0
negative regulation of cardiac cell fate specification
+
0
negative regulation of compound eye cone cell fate specification
0
negative regulation of ectodermal cell fate specification
1
negative regulation of endodermal cell fate specification
1
negative regulation of fusion cell fate specification
0
negative regulation of mesodermal cell fate specification
+
3
negative regulation of neural crest cell fate specification
0
negative regulation of retinal cone cell fate specification
0
negative regulation of terminal cell fate specification, open tracheal system
0
negative regulation of trichoblast fate specification
0