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ONTOLOGY REPORT - ANNOTATIONS


Term:methylglyoxal metabolic process
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Accession:GO:0009438 term browser browse the term
Definition:The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
Synonyms:exact_synonym: methylglyoxal metabolism
 narrow_synonym: methylglyoxal bypass;   methylglyoxal pathway
 xref: MetaCyc:METHGLYUT-PWY



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methylglyoxal metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glo1 glyoxalase 1 IDA RGD PMID:10712823 PMID:8719777 PMID:8903102 RGD:1627641, RGD:1641958, RGD:1641959 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Park7 Parkinsonism associated deglycase NOT|involved_in ISS
ISO
GO_REF:0000024
(PMID:22523093)
(PMID:27903648)
UniProt
RGD
PMID:22523093 PMID:27903648 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
cellular detoxification of methylglyoxal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS
(PMID:28993701)
GO_REF:0000024
RGD
UniProt
PMID:28993701 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
guanine deglycation, methylglyoxal removal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
GO_REF:0000024
(PMID:28596309)
UniProt
RGD
PMID:28596309 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
methylglyoxal biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A IMP RGD PMID:21890532 RGD:13673877 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Tpi1 triosephosphate isomerase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gatd1 glutamine amidotransferase class 1 domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:196,504,533...196,512,561
Ensembl chr 1:196,504,833...196,512,551
JBrowse link
G Hagh hydroxyacyl glutathione hydrolase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504
JBrowse link
G Haghl hydroxyacylglutathione hydrolase-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:14,804,957...14,809,495
Ensembl chr10:14,804,997...14,807,665
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
JBrowse link
methylglyoxal catabolic process to lactate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS
(PMID:28993701)
GO_REF:0000024
RGD
UniProt
PMID:28993701 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
protein deglycation, methylglyoxal removal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase NOT|involved_in ISS
ISO
GO_REF:0000024
(PMID:27903648)
(PMID:25416785), (PMID:30150385)
UniProt
RGD
PMID:25416785 PMID:27903648 PMID:30150385 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    metabolic process 11461
      cellular metabolic process 9699
        cellular aldehyde metabolic process 72
          methylglyoxal metabolic process 8
            cellular detoxification of methylglyoxal + 1
            methylglyoxal biosynthetic process 2
            methylglyoxal catabolic process + 5
            protein deglycation, methylglyoxal removal 1
paths to the root