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ONTOLOGY REPORT - ANNOTATIONS


Term:NAD biosynthetic process
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Accession:GO:0009435 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
Synonyms:exact_synonym: NAD anabolism;   NAD biosynthesis;   NAD formation;   NAD synthesis;   NADH biosynthesis;   NADH biosynthetic process;   nicotinamide adenine dinucleotide biosynthesis;   nicotinamide adenine dinucleotide biosynthetic process;   oxidized NAD biosynthesis;   oxidized NAD biosynthetic process;   oxidized nicotinamide adenine dinucleotide biosynthesis;   oxidized nicotinamide adenine dinucleotide biosynthetic process;   reduced NAD biosynthesis;   reduced NAD biosynthetic process;   reduced nicotinamide adenine dinucleotide biosynthesis;   reduced nicotinamide adenine dinucleotide biosynthetic process
 alt_id: GO:0006736



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NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspdh aspartate dehydrogenase domain containing involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Kynu kynureninase involved_in ISS
ISO
GO_REF:0000024
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000024 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Nadsyn1 NAD synthetase 1 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:198,981,559...199,009,806
Ensembl chr 1:198,981,604...199,009,869
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000041
(MGI:3522067|PMID:15381699)
UniProt
RGD
PMID:15381699 GO_REF:0000041 MGI:3522067 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Naprt nicotinate phosphoribosyltransferase involved_in IDA
IEA
GO_REF:0000041 UniProt
RGD
PMID:8694849 GO_REF:0000041, RGD:2289495 NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000041
(MGI:3522067|PMID:15381699), (MGI:3654729|PMID:16914673)
(MGI:6206974|PMID:27735788)
PMID:21873635
UniProt
RGD
PMID:15381699 PMID:16914673 PMID:27735788 PMID:21873635 GO_REF:0000041 MGI:3522067 MGI:3654729 MGI:6206974, RGD:13792537 NCBI chr 5:159,910,242...159,928,201
Ensembl chr 5:159,910,242...159,928,180
JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 involved_in IMP
IEA
IBA
GO_REF:0000002
GO_REF:0000041
PMID:21873635
InterPro
UniProt
RGD
PMID:22449973 PMID:21873635 GO_REF:0000002 GO_REF:0000041, RGD:13782043, RGD:13792537 NCBI chr13:65,105,950...65,277,350
Ensembl chr13:65,105,950...65,278,484
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3654729|PMID:16914673)
GO_REF:0000041
RGD
UniProt
PMID:16914673 PMID:21873635 GO_REF:0000041 MGI:3654729, RGD:13792537 NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
JBrowse link
G Qprt quinolinate phosphoribosyltransferase involved_in IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt
RGD
PMID:8694849 PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
JBrowse link
'de novo' NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nadsyn1 NAD synthetase 1 involved_in ISO
ISS
IEA
(PMID:31883644)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:31883644 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,981,559...199,009,806
Ensembl chr 1:198,981,604...199,009,869
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
NAD salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      biosynthetic process 6089
        cellular biosynthetic process 5932
          cellular nitrogen compound biosynthetic process 4904
            pyridine-containing compound biosynthetic process 24
              pyridine nucleotide biosynthetic process 19
                nicotinamide nucleotide biosynthetic process 19
                  NAD biosynthetic process 15
                    'de novo' NAD biosynthetic process + 7
                    NAD biosynthesis via nicotinamide riboside salvage pathway 0
                    NAD salvage 1
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      cellular metabolic process 10719
        cellular aromatic compound metabolic process 5635
          nucleobase-containing compound metabolic process 5410
            nucleobase-containing small molecule metabolic process 572
              nucleoside phosphate metabolic process 505
                nucleotide metabolic process 497
                  nucleotide biosynthetic process 240
                    pyridine nucleotide biosynthetic process 19
                      nicotinamide nucleotide biosynthetic process 19
                        NAD biosynthetic process 15
                          'de novo' NAD biosynthetic process + 7
                          NAD biosynthesis via nicotinamide riboside salvage pathway 0
                          NAD salvage 1
paths to the root