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ONTOLOGY REPORT - ANNOTATIONS

Term:NAD biosynthetic process
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Accession:GO:0009435 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
Synonyms:exact_synonym: NAD anabolism;   NAD biosynthesis;   NAD formation;   NAD synthesis;   NADH biosynthesis;   NADH biosynthetic process;   nicotinamide adenine dinucleotide biosynthesis;   nicotinamide adenine dinucleotide biosynthetic process;   oxidized NAD biosynthesis;   oxidized NAD biosynthetic process;   oxidized nicotinamide adenine dinucleotide biosynthesis;   oxidized nicotinamide adenine dinucleotide biosynthetic process;   reduced NAD biosynthesis;   reduced NAD biosynthetic process;   reduced nicotinamide adenine dinucleotide biosynthesis;   reduced nicotinamide adenine dinucleotide biosynthetic process
 alt_id: GO:0006736


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NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspdh aspartate dehydrogenase domain containing involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Kynu kynureninase involved_in ISS
ISO		 GO_REF:0000024
(PMID:28792876)		 UniProt
RGD		 PMID:28792876 GO_REF:0000024 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Nadsyn1 NAD synthetase 1 involved_in IEA
IBA		 GO_REF:0000041
PMID:21873635		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:198,981,559...199,009,853
Ensembl chr 1:198,981,604...199,009,869 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000041
PMID:21873635
(MGI:3522067|PMID:15381699)		 UniProt
RGD		 PMID:15381699 PMID:21873635 GO_REF:0000041 MGI:3522067, RGD:13792537 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Naprt nicotinate phosphoribosyltransferase involved_in IDA
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:8694849 GO_REF:0000041, RGD:2289495 NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102 		JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (MGI:6206974|PMID:27735788)
GO_REF:0000041
PMID:21873635
(MGI:3522067|PMID:15381699), (MGI:3654729|PMID:16914673)		 RGD
UniProt		 PMID:15381699 PMID:16914673 PMID:27735788 PMID:21873635 GO_REF:0000041 MGI:3522067 MGI:3654729 MGI:6206974, RGD:13792537 NCBI chr 5:159,910,242...159,928,201
Ensembl chr 5:159,910,242...159,928,180 		JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 involved_in IMP
IEA
IBA		 GO_REF:0000041
PMID:21873635		 UniProt
RGD		 PMID:22449973 PMID:21873635 GO_REF:0000041, RGD:13782043, RGD:13792537 NCBI chr13:65,105,950...65,277,350
Ensembl chr13:65,105,950...65,278,484 		JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
(MGI:3654729|PMID:16914673)
GO_REF:0000041		 RGD
UniProt		 PMID:16914673 PMID:21873635 GO_REF:0000041 MGI:3654729, RGD:13792537 NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645 		JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase involved_in IDA
IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt
RGD		 PMID:8694849 PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
'de novo' NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nadsyn1 NAD synthetase 1 involved_in ISO
ISS
IEA		 (PMID:31883644)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:31883644 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,981,559...199,009,853
Ensembl chr 1:198,981,604...199,009,869 		JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA		 GO_REF:0000104
PMID:21873635		 UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
NAD salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      cellular metabolic process 10124
        cellular aromatic compound metabolic process 5773
          purine-containing compound metabolic process 581
            purine nucleotide metabolic process 546
              purine nucleotide biosynthetic process 213
                NAD biosynthetic process 15
                  'de novo' NAD biosynthetic process + 7
                  NAD biosynthesis via nicotinamide riboside salvage pathway 0
                  NAD salvage 1
Path 2
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      cellular metabolic process 10124
        cellular aromatic compound metabolic process 5773
          nucleobase-containing compound metabolic process 5539
            nucleobase-containing small molecule metabolic process 684
              nucleoside phosphate metabolic process 612
                nucleotide metabolic process 602
                  nucleotide biosynthetic process 254
                    pyridine nucleotide biosynthetic process 19
                      nicotinamide nucleotide biosynthetic process 19
                        NAD biosynthetic process 15
                          'de novo' NAD biosynthetic process + 7
                          NAD biosynthesis via nicotinamide riboside salvage pathway 0
                          NAD salvage 1
paths to the root