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ONTOLOGY REPORT - ANNOTATIONS


Term:response to cold
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Accession:GO:0009409 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
Synonyms:related_synonym: freezing tolerance



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response to cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain acts_upstream_of_or_within ISO (MGI:5660099|PMID:21151927) RGD PMID:21151927 MGI:5660099 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3692446 (MGI:3692159|PMID:16121256)
Ensembl
RGD
PMID:16121256 GO_REF:0000107 MGI:3692159 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3606688 (MGI:5660099|PMID:21151927)
Ensembl
RGD
PMID:21151927 GO_REF:0000107 MGI:5660099 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Acot11 acyl-CoA thioesterase 11 acts_upstream_of_or_within ISO (PMID:11696000) RGD PMID:11696000 NCBI chr 5:121,523,833...121,581,699
Ensembl chr 5:121,527,435...121,581,538
JBrowse link
G Adm adrenomedullin IEP RGD PMID:16432587 RGD:1625324 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:87938|MGI:87939 (MGI:2387786|PMID:12161655), (MGI:2388907|PMID:12387862)
Ensembl
RGD
PMID:12161655 PMID:12387862 GO_REF:0000107 MGI:2387786 MGI:2388907 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:87937|MGI:87939 (MGI:2387786|PMID:12161655), (MGI:2388907|PMID:12387862)
Ensembl
RGD
PMID:12161655 PMID:12387862 GO_REF:0000107 MGI:2387786 MGI:2388907 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 acts_upstream_of_or_within IEP
ISO
MGI:87937|MGI:87938 (MGI:2387786|PMID:12161655), (MGI:2388907|PMID:12387862) RGD PMID:12161655 PMID:12387862 PMID:9914406 MGI:2387786 MGI:2388907, RGD:2313169 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:1857121 (MGI:3608266|PMID:12574102) RGD PMID:12574102 MGI:3608266 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 IEP RGD PMID:10777776 RGD:2317731 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Casp12 caspase 12 IEP RGD PMID:18456407 RGD:2311457 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp8 caspase 8 IEP RGD PMID:18410517 RGD:2311437 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cdh8 cadherin 8 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3707077 (MGI:3703934|PMID:17392463)
Ensembl
RGD
PMID:17392463 GO_REF:0000107 MGI:3703934 NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IEA
ISO
GO_REF:0000107
(MGI:3843740|PMID:19230830)
Ensembl
RGD
PMID:19230830 GO_REF:0000107 MGI:3843740 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Cirbp cold inducible RNA binding protein IEP RGD PMID:10641716 RGD:724747 NCBI chr 7:9,533,857...9,538,899 JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP RGD PMID:16469832 RGD:2311385 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Dio2 iodothyronine deiodinase 2 IDA RGD PMID:11934678 RGD:628323 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:16169632 RGD:2293774 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit IEP RGD PMID:16169632 RGD:2293774 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Gk glycerol kinase IEP RGD PMID:12736183 RGD:2302184 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gmpr guanosine monophosphate reductase IEP RGD PMID:9813009 RGD:70748 NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il18 interleukin 18 IEP RGD PMID:8999896 RGD:69858 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il6 interleukin 6 IEP RGD PMID:19406216 RGD:2306923 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Immt inner membrane mitochondrial protein IEP RGD PMID:17203945 RGD:1627621 NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 IEP RGD PMID:18036333 RGD:5144140 NCBI chr 4:57,801,842...57,817,434
Ensembl chr 4:57,801,831...57,819,076
JBrowse link
G LOC103690091 proSAAS acts_upstream_of_or_within ISO (MGI:3629450|PMID:16631141) RGD PMID:16631141 MGI:3629450
G Lpl lipoprotein lipase IEP RGD PMID:18722549 RGD:7241069 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp11 LDL receptor related protein 11 acts_upstream_of_or_within ISO (PMID:25262641) RGD PMID:25262641 NCBI chr 1:2,048,307...2,108,115
Ensembl chr 1:2,079,438...2,108,110
JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5574515|PMID:24906147)
GO_REF:0000002
UniProt
RGD
InterPro
PMID:24906147 GO_REF:0000002 GO_REF:0000024 MGI:5574515 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II IEP RGD PMID:8250848 RGD:2302299 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G P2rx3 purinergic receptor P2X 3 acts_upstream_of_or_within ISO MGI:1934019 (MGI:3610736|PMID:15927378) RGD PMID:15927378 MGI:3610736 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
JBrowse link
G Plac8 placenta associated 8 acts_upstream_of_or_within ISO MGI:3834141 (MGI:5302795|PMID:21982742) RGD PMID:21982742 MGI:5302795 NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
JBrowse link
G Pmch pro-melanin-concentrating hormone IMP RGD PMID:12960043 RGD:1642490 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IEP RGD PMID:17356229 RGD:5130210 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP RGD PMID:10438514 RGD:727277 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP RGD PMID:23100029 RGD:7242022 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Rbm3 RNA binding motif protein 3 acts_upstream_of_or_within ISO (MGI:3530692|PMID:15684048) RGD PMID:15684048 MGI:3530692 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580
JBrowse link
G Rgs7 regulator of G-protein signaling 7 IEP RGD PMID:18461718 RGD:13524837 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888
JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 IMP RGD PMID:31550995 RGD:150429745 NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516
JBrowse link
G Slc25a27 solute carrier family 25, member 27 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:17,306,898...17,333,942
Ensembl chr 9:17,307,023...17,332,731
JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:3038701 (MGI:3709117|PMID:17130465)
GO_REF:0000107
RGD
Ensembl
PMID:17130465 PMID:21873635 GO_REF:0000107 MGI:3709117, RGD:13792537 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Sod2 superoxide dismutase 2 IEP Acute and/or chronic stress RGD PMID:20020182 RGD:2317380 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP RGD PMID:15922484 RGD:1641989 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Thra thyroid hormone receptor alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2679056 (MGI:2677074|PMID:12869545)
Ensembl
RGD
PMID:12869545 GO_REF:0000107 MGI:2677074 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tmem135 transmembrane protein 135 acts_upstream_of_or_within ISO (MGI:5660099|PMID:21151927) RGD PMID:21151927 MGI:5660099 NCBI chr 1:143,006,343...143,279,824
Ensembl chr 1:143,006,344...143,221,171
JBrowse link
G Trh thyrotropin releasing hormone IEP RGD PMID:16629836 RGD:1600416 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3624810 (MGI:3529637|PMID:12654248), (MGI:3623714|PMID:16630838)
Ensembl
RGD
PMID:12654248 PMID:16630838 GO_REF:0000107 MGI:3529637 MGI:3623714 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 acts_upstream_of_or_within IDA
ISO
MGI:3716518|MGI:3716553|MGI:3716558 (MGI:3529637|PMID:12654248), (MGI:3696601|PMID:17015441), (MGI:3716025|PMID:17481392), (MGI:3716032|PMID:17481391), (MGI:3716047|PMID:17538622) RGD PMID:12654248 PMID:17015441 PMID:17481391 PMID:17481392 PMID:17538622 More... MGI:3529637 MGI:3696601 MGI:3716025 MGI:3716032 MGI:3716047, RGD:632416 NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552
JBrowse link
G Ucp1 uncoupling protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Ucp2 uncoupling protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 involved_in IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:9367914 PMID:21873635 RGD:2313537, RGD:13792537 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Vegfa vascular endothelial growth factor A IEP RGD PMID:10342292 RGD:2314329 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vgf VGF nerve growth factor inducible acts_upstream_of_or_within ISO (MGI:3629450|PMID:16631141) RGD PMID:16631141 MGI:3629450 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341
JBrowse link
G Zfp516 zinc finger protein 516 involved_in ISO (MGI:5616937|PMID:25578880) RGD PMID:25578880 MGI:5616937 NCBI chr18:76,286,453...76,386,526
Ensembl chr18:76,302,096...76,385,269
JBrowse link
cellular response to cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D acts_upstream_of_or_within ISO (MGI:6306193|PMID:30862682) RGD PMID:30862682 MGI:6306193 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cidea cell death-inducing DFFA-like effector a involved_in ISO (MGI:5914794|PMID:28763438) RGD PMID:28763438 MGI:5914794 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cirbp cold inducible RNA binding protein acts_upstream_of_or_within ISO (MGI:87836|PMID:9151692) RGD PMID:9151692 MGI:87836 NCBI chr 7:9,533,857...9,538,899 JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5617428|PMID:25329545)
UniProt
RGD
PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:25329545)
UniProt
RGD
PMID:25329545 GO_REF:0000024 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (PMID:25329545) RGD PMID:25329545 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630
JBrowse link
G Lipe lipase E, hormone sensitive type acts_upstream_of_or_within ISO (MGI:6306193|PMID:30862682) RGD PMID:30862682 MGI:6306193 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO MGI:6101514 (MGI:6198859|PMID:29400713) RGD PMID:29400713 MGI:6198859 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Plin1 perilipin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6306193|PMID:30862682)
GO_REF:0000107
RGD
Ensembl
PMID:30862682 GO_REF:0000107 MGI:6306193 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6306193|PMID:30862682)
GO_REF:0000107
RGD
Ensembl
PMID:30862682 GO_REF:0000107 MGI:6306193 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Rnf34 ring finger protein 34 involved_in ISO (MGI:5582154|PMID:22064484) RGD PMID:22064484 MGI:5582154 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586
JBrowse link
G Saxo1 stabilizer of axonemal microtubules 1 involved_in ISO (PMID:25673876) RGD PMID:25673876 NCBI chr 5:100,937,134...101,093,308
Ensembl chr 5:100,937,130...101,093,281
JBrowse link
G Saxol1 stabilizer of axonemal microtubules like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:27,973,442...27,975,599 JBrowse link
G Slc9a1 solute carrier family 9 member A1 IEP RGD PMID:15452191 RGD:1625557 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IMP RGD PMID:21068322 RGD:10043615 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Ucp1 uncoupling protein 1 involved_in ISO (MGI:5914794|PMID:28763438) RGD PMID:28763438 MGI:5914794 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Vwf von Willebrand factor IEP RGD PMID:12084999 RGD:11079231 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
cellular response to freezing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas2 abraxas 2, BRISC complex subunit acts_upstream_of_or_within ISO MGI:88096 (MGI:5467904|PMID:22974638) RGD PMID:22974638 MGI:5467904 NCBI chr 1:187,647,078...187,672,660
Ensembl chr 1:187,647,067...187,672,655
JBrowse link
cold acclimation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6150753|PMID:29467283) RGD PMID:29467283 MGI:6150753 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta IEP RGD PMID:9163327 RGD:13799276 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 IEP RGD PMID:9163327 RGD:13799276 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 IDA RGD PMID:21945600 RGD:6484546 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Saxo1 stabilizer of axonemal microtubules 1 involved_in ISO (PMID:25673876) RGD PMID:25673876 NCBI chr 5:100,937,134...101,093,308
Ensembl chr 5:100,937,130...101,093,281
JBrowse link
G Saxol1 stabilizer of axonemal microtubules like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:27,973,442...27,975,599 JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6306193|PMID:30862682)
GO_REF:0000107
RGD
Ensembl
PMID:30862682 GO_REF:0000107 MGI:6306193 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of_or_within ISO (MGI:6306193|PMID:30862682) RGD PMID:30862682 MGI:6306193 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    response to stimulus 10325
      response to stress 4026
        response to cold 76
          cellular response to cold + 19
          cold acclimation 6
          response to freezing + 1
          vernalization response + 0
Path 2
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  biological_process 19391
    response to stimulus 10325
      response to abiotic stimulus 1533
        response to temperature stimulus 242
          response to cold 76
            cellular response to cold + 19
            cold acclimation 6
            response to freezing + 1
            vernalization response + 0
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