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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:folic acid-containing compound biosynthetic process
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Accession:GO:0009396 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.
Synonyms:exact_synonym: folate and derivative biosynthesis;   folate and derivative biosynthetic process;   folate-containing compound biosynthesis;   folate-containing compound biosynthetic process;   folic acid and derivative biosynthesis;   folic acid and derivative biosynthetic process;   folic acid-containing compound anabolism;   folic acid-containing compound biosynthesis;   folic acid-containing compound formation;   folic acid-containing compound synthesis;   vitamin B9 and derivative biosynthesis;   vitamin B9 and derivative biosynthetic process;   vitamin M and derivative biosynthesis;   vitamin M and derivative biosynthetic process



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folic acid-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:36,370,505...36,391,314
Ensembl chr 3:36,370,300...36,391,068
JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA
(PMID:1881876)
GO_REF:0000117
(PMID:23704330)
RGD
UniProt
PMID:1881876 PMID:23704330 GO_REF:0000117 NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:100,713,681...100,781,957
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in ISO
IEA
IBA
(PMID:12937168)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:12937168 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:42,849,374...43,038,309
JBrowse link
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 TAS RGD PMID:14729668 RGD:1547843 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:124,617,217...124,664,704
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IDA RGD PMID:7057182 RGD:2301991 NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756
JBrowse link
G Dhfr dihydrofolate reductase involved_in IDA
ISO
IEA
IBA
(PMID:2303423)
GO_REF:0000041
(PMID:360074), (PMID:730776)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000117
RGD
UniProt
InterPro
GO_Central
PMID:360074 PMID:730776 PMID:2303423 PMID:11502523 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000117, RGD:1298877 NCBI chr 2:25,320,895...25,346,004 JBrowse link
G Folr1 folate receptor alpha involved_in ISO
IEA
MGI:2383986 (PMID:10508523)
GO_REF:0000107
RGD
Ensembl
PMID:10508523 GO_REF:0000107 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:165,631,462...165,642,669
JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412
JBrowse link
G Slc46a1 solute carrier family 46 member 1 involved_in ISO
IEA
(PMID:17962486)
GO_REF:0000107
RGD
Ensembl
PMID:17962486 GO_REF:0000107 NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869
JBrowse link
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase involved_in IEA
ISO
IBA
GO_REF:0000041
(PMID:25164808)
(PMID:3619447), (PMID:8408020)
(PMID:24532667), (PMID:9054377)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:3619447 PMID:8408020 PMID:9054377 PMID:24532667 PMID:25164808 GO_REF:0000033 GO_REF:0000041 NCBI chr 3:36,370,505...36,391,314
Ensembl chr 3:36,370,300...36,391,068
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 20668
    cellular process 19605
      metabolic process 12252
        modified amino acid metabolic process 206
          folic acid-containing compound metabolic process 28
            folic acid-containing compound biosynthetic process 9
              dihydrofolate biosynthetic process 0
              folic acid biosynthetic process 0
              tetrahydrofolate biosynthetic process + 8
              tetrahydrofolylpolyglutamate biosynthetic process 1
paths to the root